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Chemical Compound Review

Thiosine     (2S)-2-amino-3-(2- aminoethylsulfanyl)propa...

Synonyms: thialysine, L-Thialysine, gamma-Thia-lys, L-4-thialysine, CHEMBL397565, ...
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Disease relevance of Thiosine


High impact information on Thiosine


Chemical compound and disease context of Thiosine


Biological context of Thiosine


Anatomical context of Thiosine


Associations of Thiosine with other chemical compounds


Gene context of Thiosine


Analytical, diagnostic and therapeutic context of Thiosine


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  2. Thialysine-resistant mutant of Salmonella typhimurium with a lesion in the thrA gene. Jegede, V.A., Spencer, F., Brenchley, J.E. Genetics (1976) [Pubmed]
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  5. The Corynebacterium glutamicum aecD gene encodes a C-S lyase with alpha, beta-elimination activity that degrades aminoethylcysteine. Rossol, I., Pühler, A. J. Bacteriol. (1992) [Pubmed]
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  8. Aminoethylcysteine ketimine decarboxylated dimer protects submitochondrial particles from lipid peroxidation at a concentration not inhibitory of electron transport. Pecci, L., Fontana, M., Montefoschi, G., Cavallini, D. Biochem. Biophys. Res. Commun. (1994) [Pubmed]
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  12. Continuous spectrophotometric assay of pantetheinase activity. Duprè, S., Chiaraluce, R., Nardini, M., Cannella, C., Ricci, G., Cavallini, D. Anal. Biochem. (1984) [Pubmed]
  13. Effect of various aminoacid analogues on chick tendon procollagen synthesis and secretion: selective inhibition by S-2-aminoethyl cysteine. Jimenez, S., Benditt, M., Yankowski, R., Christner, P. Biochem. Biophys. Res. Commun. (1979) [Pubmed]
  14. Determination of aminoethylcysteine ketimine decarboxylated dimer in human plasma and cultured cells by high-performance liquid chromatography with electrochemical detection. Nardini, M., Macone, A., Matarese, R.M. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2003) [Pubmed]
  15. Changes in proteinase and peptidase activities during reticulocyte maturation. McKay, M.J., Atkinson, E.M., Worthington, V.C., Hipkiss, A.R. Biochim. Biophys. Acta (1983) [Pubmed]
  16. Lanthionine ketimine and S-(2-aminoethyl)-L-cysteine ketimine induce the tyrosyl phosphorylation of 45 kDa protein in parallel with its stimulation of superoxide generation in human neutrophils. Zhang, J., Sugahara, K., Hashimoto, K., Sagara, Y., Fontana, M., Duprè, S., Kodama, H. Physiological chemistry and physics and medical NMR. (1997) [Pubmed]
  17. Aminoethylcysteine can replace the function of the essential active site lysine of Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl coenzyme A reductase. Bochar, D.A., Tabernero, L., Stauffacher, C.V., Rodwell, V.W. Biochemistry (1999) [Pubmed]
  18. High-performance liquid chromatography of cystathionine, lanthionine and aminoethylcysteine using o-phthaldialdehyde precolumn derivatization. Costa, M., Pecci, I., Pensa, B., Fontana, M., Cavallini, D. J. Chromatogr. (1989) [Pubmed]
  19. Sulfur-containing cyclic ketimines and imino acids. A novel family of endogenous products in the search for a role. Cavallini, D., Ricci, G., Duprè, S., Pecci, L., Costa, M., Matarese, R.M., Pensa, B., Antonucci, A., Solinas, S.P., Fontana, M. Eur. J. Biochem. (1991) [Pubmed]
  20. Spermidine/spermine-N1-acetyltransferase-2 (SSAT2) acetylates thialysine and is not involved in polyamine metabolism. Coleman, C.S., Stanley, B.A., Jones, A.D., Pegg, A.E. Biochem. J. (2004) [Pubmed]
  21. Identification of aminoethylcysteine ketimine decarboxylated dimer, a natural antioxidant, in dietary vegetables. Macone, A., Nardini, M., Antonucci, A., Maggio, A., Matarese, R.M. J. Agric. Food Chem. (2002) [Pubmed]
  22. Effect of different levels of aspartokinase on the lysine production by Corynebacterium lactofermentum. Jetten, M.S., Follettie, M.T., Sinskey, A.J. Appl. Microbiol. Biotechnol. (1995) [Pubmed]
  23. Antioxidant activity of aminoethylcysteine ketimine decarboxylated dimer on copper-induced LDL oxidation. Matarese, R.M., Macone, A., Fontana, M., Duprè, S., Cavallini, D. Biochem. Mol. Biol. Int. (1998) [Pubmed]
  24. Detection of 2H-1,4-thiazine-5,6-dihydro-3-carboxylic acid (aminoethylcysteine ketimine) in the bovine brain. Nardini, M., Matarese, R.M., Pecci, L., Antonucci, A., Ricci, G., Cavallini, D. Biochem. Biophys. Res. Commun. (1990) [Pubmed]
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