Gene Review:
RGS14 - regulator of G-protein signaling 14
Homo sapiens
Synonyms:
Regulator of G-protein signaling 14
- RGS14 is a centrosomal and nuclear cytoplasmic shuttling protein that traffics to promyelocytic leukemia nuclear bodies following heat shock. Cho, H., Kim, D.U., Kehrl, J.H. J. Biol. Chem. (2005)
- RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity. Kimple, R.J., De Vries, L., Tronchère, H., Behe, C.I., Morris, R.A., Gist Farquhar, M., Siderovski, D.P. J. Biol. Chem. (2001)
- RGS14, a GTPase-activating protein for Gialpha, attenuates Gialpha- and G13alpha-mediated signaling pathways. Cho, H., Kozasa, T., Takekoshi, K., De Gunzburg, J., Kehrl, J.H. Mol. Pharmacol. (2000)
- Biochemical characterization of RGS14: RGS14 activity towards G-protein alpha subunits is independent of its binding to Rap2A. Mittal, V., Linder, M.E. Biochem. J. (2006)
- A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho. Fukuhara, S., Murga, C., Zohar, M., Igishi, T., Gutkind, J.S. J. Biol. Chem. (1999)
- Selective interactions between Gialpha1 and Gialpha3 and the GoLoco/GPR domain of RGS14 influence its dynamic subcellular localization. Shu, F.J., Ramineni, S., Amyot, W., Hepler, J.R. Cell. Signal. (2007)
- Analysis of interactions between regulator of G-protein signaling-14 and microtubules. Martin-McCaffrey, L., Willard, F.S., Pajak, A., Dagnino, L., Siderovski, D.P., D'Souza, S.J. Meth. Enzymol. (2004)
- RGS14 is a microtubule-associated protein. Martin-McCaffrey, L., Willard, F.S., Pajak, A., Dagnino, L., Siderovski, D.P., D'Souza, S.J. Cell Cycle (2005)
- RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao. Traver, S., Bidot, C., Spassky, N., Baltauss, T., De Tand, M.F., Thomas, J.L., Zalc, B., Janoueix-Lerosey, I., Gunzburg, J.D. Biochem. J. (2000)
- Localization of the GoLoco motif carrier regulator of G-protein signalling 12 and 14 proteins in monkey and rat brain. López-Aranda, M.F., Acevedo, M.J., Carballo, F.J., Gutiérrez, A., Khan, Z.U. Eur. J. Neurosci. (2006)
- Novel activity of RGS14 on Goalpha and Gialpha nucleotide binding and hydrolysis distinct from its RGS domain and GDI activity. Hepler, J.R., Cladman, W., Ramineni, S., Hollinger, S., Chidiac, P. Biochemistry (2005)
- Transcriptional changes in multiple system atrophy and Parkinson's disease putamen. Vogt, I.R., Lees, A.J., Evert, B.O., Klockgether, T., Bonin, M., Wüllner, U. Exp. Neurol. (2006)
- Molecular cloning and expression analysis of rat Rgs12 and Rgs14. Snow, B.E., Antonio, L., Suggs, S., Gutstein, H.B., Siderovski, D.P. Biochem. Biophys. Res. Commun. (1997)