Gene Review:
P2RY13 - purinergic receptor P2Y, G-protein coupled...
Homo sapiens
Synonyms:
FKSG77, G-protein coupled receptor 86, G-protein coupled receptor 94, GPCR1, GPR86, ...
Wang,
Jacobsen,
Bengtsson,
Erlinge,
von Kügelgen,
Marteau,
Communi,
Boeynaems,
Suarez Gonzalez,
Vogt,
Lees,
Evert,
Klockgether,
Bonin,
Wüllner,
- TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells. Gschwind, A., Hart, S., Fischer, O.M., Ullrich, A. EMBO J. (2003)
- A central role of EGF receptor transactivation in angiotensin II -induced cardiac hypertrophy. Shah, B.H., Catt, K.J. Trends Pharmacol. Sci. (2003)
- p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling. Sheffler, D.J., Kroeze, W.K., Garcia, B.G., Deutch, A.Y., Hufeisen, S.J., Leahy, P., Brüning, J.C., Roth, B.L. Proc. Natl. Acad. Sci. U.S.A. (2006)
- E-selectin permits communication between PAF receptors and TRPC channels in human neutrophils. McMeekin, S.R., Dransfield, I., Rossi, A.G., Haslett, C., Walker, T.R. Blood (2006)
- The peripheral cannabinoid receptor Cb2, frequently expressed on AML blasts, either induces a neutrophilic differentiation block or confers abnormal migration properties in a ligand-dependent manner. Alberich Jordà, M., Rayman, N., Tas, M., Verbakel, S.E., Battista, N., van Lom, K., Löwenberg, B., Maccarrone, M., Delwel, R. Blood (2004)
- Regulators of G protein signaling (RGS proteins): novel central nervous system drug targets. Neubig, R.R. J. Pept. Res. (2002)
- Emerging signalling and protein interactions mediated via metabotropic glutamate receptors. Moldrich, R.X., Beart, P.M. Current drug targets. CNS and neurological disorders. (2003)
- Rhodopsin: structural basis of molecular physiology. Menon, S.T., Han, M., Sakmar, T.P. Physiol. Rev. (2001)
- Cargo regulates clathrin-coated pit dynamics. Puthenveedu, M.A., von Zastrow, M. Cell (2006)
- A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription. Kang, J., Shi, Y., Xiang, B., Qu, B., Su, W., Zhu, M., Zhang, M., Bao, G., Wang, F., Zhang, X., Yang, R., Fan, F., Chen, X., Pei, G., Ma, L. Cell (2005)
- Beta-arrestin goes nuclear. Beaulieu, J.M., Caron, M.G. Cell (2005)
- Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation. Gschwind, A., Prenzel, N., Ullrich, A. Cancer Res. (2002)
- Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases. Della Rocca, G.J., Maudsley, S., Daaka, Y., Lefkowitz, R.J., Luttrell, L.M. J. Biol. Chem. (1999)
- The synthetic peptide derived from the NH2-terminal extracellular region of an orphan G protein-coupled receptor, GPR1, preferentially inhibits infection of X4 HIV-1. Jinno-Oue, A., Shimizu, N., Soda, Y., Tanaka, A., Ohtsuki, T., Kurosaki, D., Suzuki, Y., Hoshino, H. J. Biol. Chem. (2005)
- Differential regulation of estrogen receptor alpha, glucocorticoid receptor and retinoic acid receptor alpha transcriptional activity by melatonin is mediated via different G proteins. Kiefer, T.L., Lai, L., Yuan, L., Dong, C., Burow, M.E., Hill, S.M. J. Pineal Res. (2005)
- Involvement of metabotropic glutamate receptor 1, a G protein coupled receptor, in melanoma development. Marín, Y.E., Chen, S. J. Mol. Med. (2004)
- EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Prenzel, N., Zwick, E., Daub, H., Leserer, M., Abraham, R., Wallasch, C., Ullrich, A. Nature (1999)
- Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Ferguson, S.S. Pharmacol. Rev. (2001)
- The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo. Chiang, N., Serhan, C.N., Dahlén, S.E., Drazen, J.M., Hay, D.W., Rovati, G.E., Shimizu, T., Yokomizo, T., Brink, C. Pharmacol. Rev. (2006)
- G protein-coupled receptor allosterism and complexing. Christopoulos, A., Kenakin, T. Pharmacol. Rev. (2002)
- Discovery and mapping of ten novel G protein-coupled receptor genes. Lee, D.K., Nguyen, T., Lynch, K.R., Cheng, R., Vanti, W.B., Arkhitko, O., Lewis, T., Evans, J.F., George, S.R., O'Dowd, B.F. Gene (2001)
- Ocular albinism: evidence for a defect in an intracellular signal transduction system. Schiaffino, M.V., d'Addio, M., Alloni, A., Baschirotto, C., Valetti, C., Cortese, K., Puri, C., Bassi, M.T., Colla, C., De Luca, M., Tacchetti, C., Ballabio, A. Nat. Genet. (1999)
- A receptor in pituitary and hypothalamus that functions in growth hormone release. Howard, A.D., Feighner, S.D., Cully, D.F., Arena, J.P., Liberator, P.A., Rosenblum, C.I., Hamelin, M., Hreniuk, D.L., Palyha, O.C., Anderson, J., Paress, P.S., Diaz, C., Chou, M., Liu, K.K., McKee, K.K., Pong, S.S., Chaung, L.Y., Elbrecht, A., Dashkevicz, M., Heavens, R., Rigby, M., Sirinathsinghji, D.J., Dean, D.C., Melillo, D.G., Patchett, A.A., Nargund, R., Griffin, P.R., DeMartino, J.A., Gupta, S.K., Schaeffer, J.M., Smith, R.G., Van der Ploeg, L.H. Science (1996)
- ArfGAP family proteins in cell adhesion, migration and tumor invasion. Sabe, H., Onodera, Y., Mazaki, Y., Hashimoto, S. Curr. Opin. Cell Biol. (2006)
- Regulation of tyrosine kinase cascades by G-protein-coupled receptors. Luttrell, L.M., Daaka, Y., Lefkowitz, R.J. Curr. Opin. Cell Biol. (1999)
- Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway. van Biesen, T., Hawes, B.E., Luttrell, D.K., Krueger, K.M., Touhara, K., Porfiri, E., Sakaue, M., Luttrell, L.M., Lefkowitz, R.J. Nature (1995)
- D1 and NMDA receptors hook up: expanding on an emerging theme. Salter, M.W. Trends Neurosci. (2003)
- Signal characteristics of G protein-transactivated EGF receptor. Daub, H., Wallasch, C., Lankenau, A., Herrlich, A., Ullrich, A. EMBO J. (1997)
- Involvement of multiple P2Y receptors and signaling pathways in the action of adenine nucleotides diphosphates on human monocyte-derived dendritic cells. Marteau, F., Communi, D., Boeynaems, J.M., Suarez Gonzalez, N. J. Leukoc. Biol. (2004)
- Agonists and antagonists for P2 receptors. Jacobson, K.A., Costanzi, S., Joshi, B.V., Besada, P., Shin, D.H., Ko, H., Ivanov, A.A., Mamedova, L. Novartis Found. Symp. (2006)
- Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. von Kügelgen, I. Pharmacol. Ther. (2006)
- Transcriptional changes in multiple system atrophy and Parkinson's disease putamen. Vogt, I.R., Lees, A.J., Evert, B.O., Klockgether, T., Bonin, M., Wüllner, U. Exp. Neurol. (2006)
- P2 receptor mRNA expression profiles in human lymphocytes, monocytes and CD34+ stem and progenitor cells. Wang, L., Jacobsen, S.E., Bengtsson, A., Erlinge, D. BMC Immunol. (2004)
- G protein-coupled receptors: functional and mechanistic insights through altered gene expression. Rohrer, D.K., Kobilka, B.K. Physiol. Rev. (1998)
- A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders. Yokomizo, T., Kato, K., Terawaki, K., Izumi, T., Shimizu, T. J. Exp. Med. (2000)
- Techniques: GPCR assembly, pharmacology and screening by flow cytometry. Waller, A., Simons, P.C., Biggs, S.M., Edwards, B.S., Prossnitz, E.R., Sklar, L.A. Trends Pharmacol. Sci. (2004)
- Chimaeric G alpha proteins: their potential use in drug discovery. Milligan, G., Rees, S. Trends Pharmacol. Sci. (1999)
- Trace amines: identification of a family of mammalian G protein-coupled receptors. Borowsky, B., Adham, N., Jones, K.A., Raddatz, R., Artymyshyn, R., Ogozalek, K.L., Durkin, M.M., Lakhlani, P.P., Bonini, J.A., Pathirana, S., Boyle, N., Pu, X., Kouranova, E., Lichtblau, H., Ochoa, F.Y., Branchek, T.A., Gerald, C. Proc. Natl. Acad. Sci. U.S.A. (2001)