Gene Review:
Myo5a - myosin VA
Mus musculus
Synonyms:
9630007J19Rik, AI413174, AI661011, Dbv, Dilute, ...
Kang-Decker,
Hammer ,
Rivkin,
Wenthold,
Kierszenbaum,
Petralia,
Tres,
Sans,
Rivkin,
Wang,
Tres,
Worley,
Kierszenbaum,
van Deursen,
- Characterization of the molecular defects in Rab27a, caused by RAB27A missense mutations found in patients with Griscelli syndrome. Bahadoran, P., Busca, R., Chiaverini, C., Westbroek, W., Lambert, J., Bille, K., Valony, G., Fukuda, M., Naeyaert, J.M., Ortonne, J.P., Ballotti, R. J. Biol. Chem. (2003)
- Expression of constructs of the neuronal isoform of myosin-Va interferes with the distribution of melanosomes and other vesicles in melanoma cells. da Silva Bizario, J.C., da Cunha Nascimento, A.A., Casaletti, L., Patussi, E.V., Chociay, M.F., Larson, R.E., Espreafico, E.M. Cell Motil. Cytoskeleton (2002)
- Myosin Va and microtubule-based motors are required for fast axonal retrograde transport of tetanus toxin in motor neurons. Lalli, G., Gschmeissner, S., Schiavo, G. J. Cell. Sci. (2003)
- Activation of myosin Va function by melanophilin, a specific docking partner of myosin Va. Li, X.D., Ikebe, R., Ikebe, M. J. Biol. Chem. (2005)
- Identification of mRNA/protein (mRNP) complexes containing Puralpha, mStaufen, fragile X protein, and myosin Va and their association with rough endoplasmic reticulum equipped with a kinesin motor. Ohashi, S., Koike, K., Omori, A., Ichinose, S., Ohara, S., Kobayashi, S., Sato, T.A., Anzai, K. J. Biol. Chem. (2002)
- Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene. Pastural, E., Barrat, F.J., Dufourcq-Lagelouse, R., Certain, S., Sanal, O., Jabado, N., Seger, R., Griscelli, C., Fischer, A., de Saint Basile, G. Nat. Genet. (1997)
- Pigment cells: a model for the study of organelle transport. Nascimento, A.A., Roland, J.T., Gelfand, V.I. Annu. Rev. Cell Dev. Biol. (2003)
- Direct interaction of microtubule- and actin-based transport motors. Huang, J.D., Brady, S.T., Richards, B.W., Stenolen, D., Resau, J.H., Copeland, N.G., Jenkins, N.A. Nature (1999)
- Identification of an organelle receptor for myosin-Va. Wu, X.S., Rao, K., Zhang, H., Wang, F., Sellers, J.R., Matesic, L.E., Copeland, N.G., Jenkins, N.A., Hammer, J.A. Nat. Cell Biol. (2002)
- Loss of heterozygosity at the dilute-short ear (Myo5a-Bmp5) region of the mouse: mitotic recombination or double non-disjunction? Favor, J., Neuhäuser-Klaus, A. Genet. Res. (1998)
- Identification of a novel myosin-Va mutation in an ataxic mutant rat, dilute-opisthotonus. Futaki, S., Takagishi, Y., Hayashi, Y., Ohmori, S., Kanou, Y., Inouye, M., Oda, S., Seo, H., Iwaikawa, Y., Murata, Y. Mamm. Genome (2000)
- Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density. Rao, M.V., Engle, L.J., Mohan, P.S., Yuan, A., Qiu, D., Cataldo, A., Hassinger, L., Jacobsen, S., Lee, V.M., Andreadis, A., Julien, J.P., Bridgman, P.C., Nixon, R.A. J. Cell Biol. (2002)
- Rab27a is an essential component of melanosome receptor for myosin Va. Wu, X., Wang, F., Rao, K., Sellers, J.R., Hammer, J.A. Mol. Biol. Cell (2002)
- Melanophilin and myosin Va track the microtubule plus end on EB1. Wu, X.S., Tsan, G.L., Hammer, J.A. J. Cell Biol. (2005)
- The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a. Jones, J.M., Huang, J.D., Mermall, V., Hamilton, B.A., Mooseker, M.S., Escayg, A., Copeland, N.G., Jenkins, N.A., Meisler, M.H. Hum. Mol. Genet. (2000)
- Melanophilin, the product of the leaden locus, is required for targeting of myosin-Va to melanosomes. Provance, D.W., James, T.L., Mercer, J.A. Traffic (2002)
- Effects of some excitatory amino acid antagonists and drugs enhancing gamma-aminobutyric acid neurotransmission on pefloxacin-induced seizures in DBA/2 mice. De Sarro, G., Nava, F., Calapai, G., De Sarro, A. Antimicrob. Agents Chemother. (1997)
- Gabapentin potentiates the antiseizure activity of certain anticonvulsants in DBA/2 mice. De Sarro, G., Spagnolo, C., Gareri, P., Gallelli, L., De Sarro, A. Eur. J. Pharmacol. (1998)
- The actin-based motor myosin Va is a component of the acroplaxome, an acrosome-nuclear envelope junctional plate, and of manchette-associated vesicles. Kierszenbaum, A.L., Rivkin, E., Tres, L.L. Cytogenet. Genome Res. (2003)
- Glutamate receptor targeting in the postsynaptic spine involves mechanisms that are independent of myosin Va. Petralia, R.S., Wang, Y.X., Sans, N., Worley, P.F., Hammer , J.A., Wenthold, R.J. Eur. J. Neurosci. (2001)
- Ca2+-induced activation of ATPase activity of myosin Va is accompanied with a large conformational change. Li, X.D., Mabuchi, K., Ikebe, R., Ikebe, M. Biochem. Biophys. Res. Commun. (2004)
- The actin-binding domain of Slac2-a/melanophilin is required for melanosome distribution in melanocytes. Kuroda, T.S., Ariga, H., Fukuda, M. Mol. Cell. Biol. (2003)
- Identification of a minimal myosin Va binding site within an intrinsically unstructured domain of melanophilin. Geething, N.C., Spudich, J.A. J. Biol. Chem. (2007)
- Human myosin-Vc is a novel class V myosin expressed in epithelial cells. Rodriguez, O.C., Cheney, R.E. J. Cell. Sci. (2002)
- The acroplaxome is the docking site of Golgi-derived myosin Va/Rab27a/b- containing proacrosomal vesicles in wild-type and Hrb mutant mouse spermatids. Kierszenbaum, A.L., Tres, L.L., Rivkin, E., Kang-Decker, N., van Deursen, J.M. Biol. Reprod. (2004)
- Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport. Fukuda, M., Kuroda, T.S., Mikoshiba, K. J. Biol. Chem. (2002)