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Gene Review

Polg  -  polymerase (DNA directed), gamma

Mus musculus

Synonyms: AA409516, DNA polymerase subunit gamma-1, Mitochondrial DNA polymerase catalytic subunit, Pol gamma, PolG-alpha, ...
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  1. Mitochondrial DNA polymerase gamma is essential for mammalian embryogenesis. Hance, N., Ekstrand, M.I., Trifunovic, A. Hum. Mol. Genet. (2005) [Pubmed]
  2. DNA polymerases as targets of anticancer nucleosides. Miura, S., Izuta, S. Current drug targets. (2004) [Pubmed]
  3. Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase gamma, Pol gamma B, functions as a homodimer. Carrodeguas, J.A., Theis, K., Bogenhagen, D.F., Kisker, C. Mol. Cell (2001) [Pubmed]
  4. Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice. Demeilliers, C., Maisonneuve, C., Grodet, A., Mansouri, A., Nguyen, R., Tinel, M., Lettéron, P., Degott, C., Feldmann, G., Pessayre, D., Fromenty, B. Gastroenterology (2002) [Pubmed]
  5. Tacrine inhibits topoisomerases and DNA synthesis to cause mitochondrial DNA depletion and apoptosis in mouse liver. Mansouri, A., Haouzi, D., Descatoire, V., Demeilliers, C., Sutton, A., Vadrot, N., Fromenty, B., Feldmann, G., Pessayre, D., Berson, A. Hepatology (2003) [Pubmed]
  6. Sequence and insertion sites of murine melanoma-associated retrovirus. Li, M., Huang, X., Zhu, Z., Gorelik, E. J. Virol. (1999) [Pubmed]
  7. Mitochondrial DNA mutators. Foury, F., Hu, J., Vanderstraeten, S. Cell. Mol. Life Sci. (2004) [Pubmed]
  8. Mitochondrial DNA polymerases from yeast to man: a new family of polymerases. Lecrenier, N., Van Der Bruggen, P., Foury, F. Gene (1997) [Pubmed]
  9. Mitochondrial DNA integrity is not dependent on DNA polymerase-beta activity. Hansen, A.B., Griner, N.B., Anderson, J.P., Kujoth, G.C., Prolla, T.A., Loeb, L.A., Glick, E. DNA Repair (Amst.) (2006) [Pubmed]
  10. Changes of mitochondrial DNA polymerase-gamma activity in synchronized mouse cell cultures. Radsak, K., Schütz, E. Eur. J. Biochem. (1978) [Pubmed]
  11. Identification of a polypeptide component of mouse myeloma DNA polymerase gamma. Matsukage, A., Tanabe, K., Yamaguchi, M., Taguchi, Y.N., Nishizawa, M., Takahashi, T., Takahashi, T. Biochim. Biophys. Acta (1981) [Pubmed]
  12. 2'-Fluoro-2'-deoxypolynucleotides as templates and inhibitors for RNA- and DNA-dependent DNA polymerases. Aoyama, H., Sarih-Cottin, L., Tarrago-Litvak, L., Kakiuchi, N., Litvak, S., Guschlbauer, W. Biochim. Biophys. Acta (1985) [Pubmed]
  13. Three cytoplasmic DNA polymerases that utilize poly(rA).oligo(dT). Goulian, M., Grimm, S.L. Biochem. Biophys. Res. Commun. (1990) [Pubmed]
  14. Differential inhibition of various mammalian DNA polymerase activities by ammonium 21-tungsto-9-antimoniate (HPA23). Ono, K., Nakane, H., Barré-Sinoussi, F., Chermann, J.C. Eur. J. Biochem. (1988) [Pubmed]
  15. Effects of 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate. Parker, W.B., Shaddix, S.C., Chang, C.H., White, E.L., Rose, L.M., Brockman, R.W., Shortnacy, A.T., Montgomery, J.A., Secrist, J.A., Bennett, L.L. Cancer Res. (1991) [Pubmed]
  16. p53 functions in the incorporation step in DNA base excision repair in mouse liver mitochondria. de Souza-Pinto, N.C., Harris, C.C., Bohr, V.A. Oncogene (2004) [Pubmed]
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