Gene Review:
St8sia1 - ST8 alpha-N-acetyl-neuraminide alpha-2,8...
Mus musculus
Synonyms:
9330109E03Rik, Alpha-2,8-sialyltransferase 8A, Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase, GD3 synthase, GD3S, ...
- GD3 synthase gene knockout mice exhibit thermal hyperalgesia and mechanical allodynia but decreased response to formalin-induced prolonged noxious stimulation. Handa, Y., Ozaki, N., Honda, T., Furukawa, K., Tomita, Y., Inoue, M., Furukawa, K., Okada, M., Sugiura, Y. Pain (2005)
- Glycosylation pathways in the biosynthesis of gangliosides in melanoma and neuroblastoma cells: relative glycosyltransferase levels determine ganglioside patterns. Ruan, S., Lloyd, K.O. Cancer Res. (1992)
- Reduced cell migration, tumor growth and experimental metastasis of rat F-11 cells whose expression of GD3-synthase is suppressed. Zeng, G., Gao, L., Yu, R.K. Int. J. Cancer (2000)
- Suppression of ganglioside GD3 expression in a rat F-11 tumor cell line reduces tumor growth, angiogenesis, and vascular endothelial growth factor production. Zeng, G., Gao, L., Birklé, S., Yu, R.K. Cancer Res. (2000)
- a-Series gangliosides mediate the effects of advanced glycation end products on pericyte and mesangial cell proliferation: a common mediator for retinal and renal microangiopathy? Masson, E., Troncy, L., Ruggiero, D., Wiernsperger, N., Lagarde, M., Bawab, S.E. Diabetes (2005)
- Disialoganglioside (GD3) synthase gene expression suppresses vascular smooth muscle cell responses via the inhibition of ERK1/2 phosphorylation, cell cycle progression, and matrix metalloproteinase-9 expression. Moon, S.K., Kim, H.M., Lee, Y.C., Kim, C.H. J. Biol. Chem. (2004)
- Molecular cloning of Sia alpha 2,3Gal beta 1,4GlcNAc alpha 2,8-sialyltransferase from mouse brain. Yoshida, Y., Kojima, N., Kurosawa, N., Hamamoto, T., Tsuji, S. J. Biol. Chem. (1995)
- Molecular cloning and characterization of a third type of N-glycan alpha 2,8-sialyltransferase from mouse lung. Yoshida, Y., Kojima, N., Tsuji, S. J. Biochem. (1995)
- Refractory skin injury in complex knock-out mice expressing only the GM3 ganglioside. Inoue, M., Fujii, Y., Furukawa, K., Okada, M., Okumura, K., Hayakawa, T., Furukawa, K., Sugiura, Y. J. Biol. Chem. (2002)
- Expression cloning of rat cDNA encoding UDP-galactose:GD2 beta1,3-galactosyltransferase that determines the expression of GD1b/GM1/GA1. Miyazaki, H., Fukumoto, S., Okada, M., Hasegawa, T., Furukawa, K. J. Biol. Chem. (1997)
- Heterogeneity in the expression pattern of two ganglioside synthase genes during mouse brain development. Yamamoto, A., Haraguchi, M., Yamashiro, S., Fukumoto, S., Furukawa, K., Takamiya, K., Atsuta, M., Shiku, H., Furukawa, K. J. Neurochem. (1996)
- Unique genomic structure and expression of the mouse alpha 2,8-sialyltransferase (ST8Sia III) gene. Yoshida, Y., Kurosawa, N., Kanematsu, T., Taguchi, A., Arita, M., Kojima, N., Tsuji, S. Glycobiology (1996)
- Glycolipid sialyltransferases are enhanced during neural differentiation of mouse embryonic carcinoma cells, P19. Osanai, T., Watanabe, Y., Sanai, Y. Biochem. Biophys. Res. Commun. (1997)
- GD3 synthase gene found expressed in dental epithelium and shown to regulate cell proliferation. Yamada, A., Fukumoto, E., Kamasaki, Y., Ida-Yonemochi, H., Saku, T., Fujiwara, T., Fukumoto, S. Arch. Oral Biol. (2005)
- Induction of cholinergic differentiation with neurite sprouting by de novo biosynthesis and expression of GD3 and b-series gangliosides in Neuro2a cells. Kojima, N., Kurosawa, N., Nishi, T., Hanai, N., Tsuji, S. J. Biol. Chem. (1994)
- Isolation of 10 differentially expressed cDNAs in differentiated Neuro2a cells induced through controlled expression of the GD3 synthase gene. Liu, H., Nakagawa, T., Kanematsu, T., Uchida, T., Tsuji, S. J. Neurochem. (1999)
- Ganglioside GD3 biosynthesis in normal and mutant mouse embryos. Novikov, A.M., Seyfried, T.N. Biochem. Genet. (1991)
- Activation of Fas receptor is required for the increased formation of the disialoganglioside GD3 in cultured cerebellar granule cells committed to apoptotic death. Castiglione, M., Spinsanti, P., Iacovelli, L., Lenti, L., Martini, F., Gradini, R., Di Giorgi Gerevini, V., Caricasole, A., Caruso, A., De Maria, R., Nicoletti, F., Melchiorri, D. Neuroscience (2004)
- Mice expressing only monosialoganglioside GM3 exhibit lethal audiogenic seizures. Kawai, H., Allende, M.L., Wada, R., Kono, M., Sango, K., Deng, C., Miyakawa, T., Crawley, J.N., Werth, N., Bierfreund, U., Sandhoff, K., Proia, R.L. J. Biol. Chem. (2001)
- Molecular cloning and expression of a sixth type of alpha 2,8-sialyltransferase (ST8Sia VI) that sialylates O-glycans. Takashima, S., Ishida, H.K., Inazu, T., Ando, T., Ishida, H., Kiso, M., Tsuji, S., Tsujimoto, M. J. Biol. Chem. (2002)
- Chromosome mapping of the GD3 synthase gene (SIAT8) in human and mouse. Matsuda, Y., Nara, K., Watanabe, Y., Saito, T., Sanai, Y. Genomics (1996)
- Molecular cloning of cDNA for rat brain GD3-synthase. Zeng, G., Gao, L., Ariga, T., Yu, R.K. Biochem. Biophys. Res. Commun. (1996)