Gene Review:
St3gal5 - ST3 beta-galactoside alpha-2,3...
Mus musculus
Synonyms:
3S-T, CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase, GM3 synthase, GM3-specific sialytransferase, GM3S, ...
- Substitution of the N-glycan function in glycosyltransferases by specific amino acids: ST3Gal-V as a model enzyme. Uemura, S., Kurose, T., Suzuki, T., Yoshida, S., Ito, M., Saito, M., Horiuchi, M., Inagaki, F., Igarashi, Y., Inokuchi, J. Glycobiology (2006)
- Interleukin-3-associated expression of gangliosides in mouse myelogenous leukemia NFS60 cells introduced with interleukin-3 gene: expression of ganglioside GD1a and key involvement of CMP-NeuAc:lactosylceramide alpha 2-->3-sialyltransferase in GD1a expression. Tsunoda, A., Nakamura, M., Kirito, K., Hara, K., Saito, M. Biochemistry (1995)
- Endogenously produced ganglioside GM3 endows etoposide and doxorubicin resistance by up-regulating Bcl-2 expression in 3LL Lewis lung carcinoma cells. Noguchi, M., Kabayama, K., Uemura, S., Kang, B.W., Saito, M., Igarashi, Y., Inokuchi, J. Glycobiology (2006)
- Interruption of ganglioside synthesis produces central nervous system degeneration and altered axon-glial interactions. Yamashita, T., Wu, Y.P., Sandhoff, R., Werth, N., Mizukami, H., Ellis, J.M., Dupree, J.L., Geyer, R., Sandhoff, K., Proia, R.L. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Reversion of the Jun-induced oncogenic phenotype by enhanced synthesis of sialosyllactosylceramide (GM3 ganglioside). Miura, Y., Kainuma, M., Jiang, H., Velasco, H., Vogt, P.K., Hakomori, S. Proc. Natl. Acad. Sci. U.S.A. (2004)
- a-Series gangliosides mediate the effects of advanced glycation end products on pericyte and mesangial cell proliferation: a common mediator for retinal and renal microangiopathy? Masson, E., Troncy, L., Ruggiero, D., Wiernsperger, N., Lagarde, M., Bawab, S.E. Diabetes (2005)
- Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins. Tsukamoto, K., Kohda, T., Mukamoto, M., Takeuchi, K., Ihara, H., Saito, M., Kozaki, S. J. Biol. Chem. (2005)
- Sialylation and sulfation of lactosylceramide distinctly regulate anchorage-independent growth, apoptosis, and gene expression in 3LL Lewis lung carcinoma cells. Uemura, S., Kabayama, K., Noguchi, M., Igarashi, Y., Inokuchi, J. Glycobiology (2003)
- Molecular cloning and functional expression of a fifth-type alpha 2,3-sialyltransferase (mST3Gal V: GM3 synthase). Kono, M., Takashima, S., Liu, H., Inoue, M., Kojima, N., Lee, Y.C., Hamamoto, T., Tsuji, S. Biochem. Biophys. Res. Commun. (1998)
- Molecular identification, tissue distribution and subcellular localization of mST3GalV/GM3 synthase. Stern, C.A., Braverman, T.R., Tiemeyer, M. Glycobiology (2000)
- Expression cloning of mouse cDNA of CMP-NeuAc:Lactosylceramide alpha2,3-sialyltransferase, an enzyme that initiates the synthesis of gangliosides. Fukumoto, S., Miyazaki, H., Goto, G., Urano, T., Furukawa, K., Furukawa, K. J. Biol. Chem. (1999)
- Developmental patterns of mST3GalV mRNA expression in the mouse: in situ hybridization using DIG-labeled RNA probes. Ji, M.Y., Lee, Y.C., Do, S., Nam, S.Y., Jung, K.Y., Kim, H.M., Park, L.K., Choo, Y.K. Arch. Pharm. Res. (2000)
- Ganglioside GM3 participates in the pathological conditions of insulin resistance. Tagami, S., Inokuchi Ji, J., Kabayama, K., Yoshimura, H., Kitamura, F., Uemura, S., Ogawa, C., Ishii, A., Saito, M., Ohtsuka, Y., Sakaue, S., Igarashi, Y. J. Biol. Chem. (2002)
- Expression cloning of rat cDNA encoding UDP-galactose:GD2 beta1,3-galactosyltransferase that determines the expression of GD1b/GM1/GA1. Miyazaki, H., Fukumoto, S., Okada, M., Hasegawa, T., Furukawa, K. J. Biol. Chem. (1997)
- Stimulation of glycosphingolipid biosynthesis by L-threo-1-phenyl-2-decanoylamino-1-propanol and its homologs in B16 melanoma cells. Inokuchi, J., Usuki, S., Jimbo, M. J. Biochem. (1995)
- Changes in the glycolipid composition and characteristic activation of GM3 synthase in the thymus of mouse after administration of dexamethasone. Iwamori, M., Iwamori, Y. Glycoconj. J. (2005)
- Sp1 and AP2 enhance promoter activity of the mouse GM3-synthase gene. Xia, T., Zeng, G., Gao, L., Yu, R.K. Gene (2005)
- Plasma membrane production of ceramide from ganglioside GM3 in human fibroblasts. Valaperta, R., Chigorno, V., Basso, L., Prinetti, A., Bresciani, R., Preti, A., Miyagi, T., Sonnino, S. FASEB J. (2006)
- A ganglioside-specific sialyltransferase localizes to axons and non-Golgi structures in neurons. Stern, C.A., Tiemeyer, M. J. Neurosci. (2001)
- Combinatorial PCR approach to homology-based cloning: cloning and expression of mouse and human GM3-synthase. Kapitonov, D., Bieberich, E., Yu, R.K. Glycoconj. J. (1999)
- Pathophysiological implication of ganglioside GM3 in early mouse embryonic development through apoptosis. Ju, E.J., Kwak, D.H., Lee, D.H., Kim, S.M., Kim, J.S., Kim, S.M., Choi, H.G., Jung, K.Y., Lee, S.U., Do, S.I., Park, Y.I., Choo, Y.K. Arch. Pharm. Res. (2005)