Gene Review:
HGFAC - HGF activator
Homo sapiens
Synonyms:
HGFA, HGFAP, Hepatocyte growth factor activator
Nagashima,
Hasegawa,
Kato,
Yamazaki,
Nishigai,
Ishiwata,
Asano,
Yoshino,
Kataoka,
Shimomura,
Kawaguchi,
Hamasuna,
Itoh,
Kitamura,
Miyazawa,
Koono,
Kataoka,
Meng,
Itoh,
Hamasuna,
Shimomura,
Suganuma,
Koono,
Kataoka,
Miyata,
Uchinokura,
Itoh,
Kirchhofer,
Peek,
Li,
Stamos,
Eigenbrot,
Kadkhodayan,
Elliott,
Corpuz,
Lazarus,
Moran,
Kataoka,
Hamasuna,
Itoh,
Kitamura,
Koono,
- Functional analysis of HGF/MET signaling and aberrant HGF-activator expression in diffuse large B-cell lymphoma. Tjin, E.P., Groen, R.W., Vogelzang, I., Derksen, P.W., Klok, M.D., Meijer, H.P., van Eeden, S., Pals, S.T., Spaargaren, M. Blood (2006)
- Activation of hepatocyte growth factor/scatter factor in colorectal carcinoma. Kataoka, H., Hamasuna, R., Itoh, H., Kitamura, N., Koono, M. Cancer Res. (2000)
- Multiple myeloma cells catalyze hepatocyte growth factor (HGF) activation by secreting the serine protease HGF-activator. Tjin, E.P., Derksen, P.W., Kataoka, H., Spaargaren, M., Pals, S.T. Blood (2004)
- Role of hepatocyte growth factor activator (HGF activator) in invasive growth of human glioblastoma cells in vivo. Uchinokura, S., Miyata, S., Fukushima, T., Itoh, H., Nakano, S., Wakisaka, S., Kataoka, H. Int. J. Cancer (2006)
- Hepatocyte growth factor activator inhibitor type 1 is a specific cell surface binding protein of hepatocyte growth factor activator (HGFA) and regulates HGFA activity in the pericellular microenvironment. Kataoka, H., Shimomura, T., Kawaguchi, T., Hamasuna, R., Itoh, H., Kitamura, N., Miyazawa, K., Koono, M. J. Biol. Chem. (2000)
- Molecular cloning and sequence analysis of the cDNA for a human serine protease reponsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XII. Miyazawa, K., Shimomura, T., Kitamura, A., Kondo, J., Morimoto, Y., Kitamura, N. J. Biol. Chem. (1993)
- Activation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator. Miyazawa, K., Shimomura, T., Kitamura, N. J. Biol. Chem. (1996)
- Tissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1. Kirchhofer, D., Peek, M., Li, W., Stamos, J., Eigenbrot, C., Kadkhodayan, S., Elliott, J.M., Corpuz, R.T., Lazarus, R.A., Moran, P. J. Biol. Chem. (2003)
- Localization of hepatocyte growth factor activator inhibitor type 1 in Langhans' cells of human placenta. Kataoka, H., Meng, J.Y., Itoh, H., Hamasuna, R., Shimomura, T., Suganuma, T., Koono, M. Histochem. Cell Biol. (2000)
- Roles of hepatocyte growth factor activator (HGFA) and its inhibitor HAI-1 in the regeneration of injured gastrointestinal mucosa. Itoh, H., Kataoka, H. J. Gastroenterol. (2002)
- Pericellular activation of hepatocyte growth factor/scatter factor (HGF/SF) in colorectal carcinomas: roles of HGF activator (HGFA) and HGFA inhibitor type 1 (HAI-1). Kataoka, H., Itoh, H., Hamasuna, R., Meng, J.Y., Koono, M. Hum. Cell (2001)
- Functional characterization of Kunitz domains in hepatocyte growth factor activator inhibitor type 2. Qin, L., Denda, K., Shimomura, T., Kawaguchi, T., Kitamura, N. FEBS Lett. (1998)
- Activation of hepatocyte growth factor by two homologous proteases, blood-coagulation factor XIIa and hepatocyte growth factor activator. Shimomura, T., Miyazawa, K., Komiyama, Y., Hiraoka, H., Naka, D., Morimoto, Y., Kitamura, N. Eur. J. Biochem. (1995)
- Hepatocyte growth factor activator inhibitor types 1 and 2 are expressed by tubular epithelium in kidney and down-regulated in renal cell carcinoma. Yamauchi, M., Kataoka, H., Itoh, H., Seguchi, T., Hasui, Y., Osada, Y. J. Urol. (2004)
- Concomitant expression of hepatocyte growth factor (HGF), HGF activator and c-met genes in human glioma cells in vitro. Moriyama, T., Kataoka, H., Tsubouchi, H., Koono, M. FEBS Lett. (1995)
- Roles of hepatocyte growth factor (HGF) activator and HGF activator inhibitor in the pericellular activation of HGF/scatter factor. Kataoka, H., Miyata, S., Uchinokura, S., Itoh, H. Cancer Metastasis Rev. (2003)
- Fine mapping a quantitative trait locus affecting ovulation rate in swine on chromosome 8. Campbell, E.M., Nonneman, D., Rohrer, G.A. J. Anim. Sci. (2003)
- Activation of the zymogen of hepatocyte growth factor activator by thrombin. Shimomura, T., Kondo, J., Ochiai, M., Naka, D., Miyazawa, K., Morimoto, Y., Kitamura, N. J. Biol. Chem. (1993)
- Defect of pro-hepatocyte growth factor activation by fibroblasts in idiopathic pulmonary fibrosis. Marchand-Adam, S., Fabre, A., Mailleux, A.A., Marchal, J., Quesnel, C., Kataoka, H., Aubier, M., Dehoux, M., Soler, P., Crestani, B. Am. J. Respir. Crit. Care Med. (2006)
- Hepatocyte growth factor (HGF), HGF activator, and c-Met in synovial tissues in rheumatoid arthritis and osteoarthritis. Nagashima, M., Hasegawa, J., Kato, K., Yamazaki, J., Nishigai, K., Ishiwata, T., Asano, G., Yoshino, S. J. Rheumatol. (2001)
- Astroglial expression of hepatocyte growth factor and hepatocyte growth factor activator in human brain tissues. Yamada, T., Yoshiyama, Y., Tsuboi, Y., Shimomura, T. Brain Res. (1997)
- Hepatocyte growth factor (HGF) activator expressed in hair follicles is involved in in vitro HGF-dependent hair follicle elongation. Lee, Y.R., Yamazaki, M., Mitsui, S., Tsuboi, R., Ogawa, H. J. Dermatol. Sci. (2001)