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Gene Review

MT1XP1  -  metallothionein 1X pseudogene 1

Homo sapiens

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Disease relevance of MTL1

 

Psychiatry related information on MTL1

 

High impact information on MTL1

 

Chemical compound and disease context of MTL1

 

Biological context of MTL1

 

Anatomical context of MTL1

 

Associations of MTL1 with chemical compounds

 

Other interactions of MTL1

  • The other four genes are highly expressed in young fruit with reduced expression in the later stages of fruit development. pKIWI504 has strong homology to plant metallothionein-like proteins and pKIWI505 exhibits homology to the beta-subunit of the mitochondrial ATP synthase gene [24].
  • Seven genes identified as BSS-abundant genes encoded PEP carboxykinase, salt-inducible SalT homolog, heavy metal-inducible metallothionein-like protein, ABA- and drought-inducible glycine-rich protein, and three proteins of unknown function (one of which was named Bss1) [25].
 

Analytical, diagnostic and therapeutic context of MTL1

References

  1. The N-terminal portion of growth inhibitory factor is sufficient for biological activity. Uchida, Y., Ihara, Y. J. Biol. Chem. (1995) [Pubmed]
  2. Synthesis of a metallothionein-like protein in cultured human skin fibroblasts: relation to abnormal copper distribution in Menkes' disease. Bonewitz, R.F., Howell, R.R. J. Cell. Physiol. (1981) [Pubmed]
  3. Induction of metallothionein-like protein in human breast tumor cells. Bazzell, K.L., Coleman, R.L., Nordquist, R.E. Toxicol. Appl. Pharmacol. (1979) [Pubmed]
  4. Tolerance changes of the potworm Enchytraeus albidus after long-term exposure to cadmium. Lock, K., Janssen, C.R. Sci. Total Environ. (2001) [Pubmed]
  5. Growth-inhibitory factor, metallothionein-like protein, and neurodegenerative diseases. Uchida, Y. Biol. Signals (1994) [Pubmed]
  6. The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein. Uchida, Y., Takio, K., Titani, K., Ihara, Y., Tomonaga, M. Neuron (1991) [Pubmed]
  7. Cloning of the mating type loci from Pyrenopeziza brassicae reveals the presence of a novel mating type gene within a discomycete MAT 1-2 locus encoding a putative metallothionein-like protein. Singh, G., Ashby, A.M. Mol. Microbiol. (1998) [Pubmed]
  8. Nucleotide sequence of cDNA clone encoding a metallothionein-like protein from Chinese cabbage. Kim, H.U., Kim, J.B., Yun, C.H., Kang, S.K., Chung, T.Y. Plant Physiol. (1995) [Pubmed]
  9. Evidence for a dynamic structure of human neuronal growth inhibitory factor and for major rearrangements of its metal-thiolate clusters. Faller, P., Hasler, D.W., Zerbe, O., Klauser, S., Winge, D.R., Vasák, M. Biochemistry (1999) [Pubmed]
  10. Distinct metal-thiolate clusters in the N-terminal domain of neuronal growth inhibitory factor. Faller, P., Vasák, M. Biochemistry (1997) [Pubmed]
  11. The stimulation of metallothionein synthesis in neuroblastoma IMR-32 by zinc and cadmium but not dexamethasone. Ebadi, M., Takahashi, T., Timmins, P. Biological trace element research. (1989) [Pubmed]
  12. Phenotypic switching and mating type switching of Candida glabrata at sites of colonization. Brockert, P.J., Lachke, S.A., Srikantha, T., Pujol, C., Galask, R., Soll, D.R. Infect. Immun. (2003) [Pubmed]
  13. Muscarinic toxin-like proteins from cobra venom. Kukhtina, V.V., Weise, C., Muranova, T.A., Starkov, V.G., Franke, P., Hucho, F., Wnendt, S., Gillen, C., Tsetlin, V.I., Utkin, Y.N. Eur. J. Biochem. (2000) [Pubmed]
  14. Characterisation of an mRNA encoding a metallothionein-like protein that accumulates during ethylene-promoted abscission of Sambucus nigra L. leaflets. Coupe, S.A., Taylor, J.E., Roberts, J.A. Planta (1995) [Pubmed]
  15. A novel stress-inducible metallothionein-like gene from rice. Hsieh, H.M., Liu, W.K., Huang, P.C. Plant Mol. Biol. (1995) [Pubmed]
  16. Metal-thiolate clusters in the C-terminal domain of human neuronal growth inhibitory factor (GIF). Hasler, D.W., Faller, P., Vasák, M. Biochemistry (1998) [Pubmed]
  17. Localization of metals in cells of pterygote insects. Ballan-Dufrançais, C. Microsc. Res. Tech. (2002) [Pubmed]
  18. Metallothionein-like proteins in human placenta and fetal membranes. Waalkes, M.P., Poisner, A.M., Wood, G.W., Klaassen, C.D. Toxicol. Appl. Pharmacol. (1984) [Pubmed]
  19. Binding of lead to a metallothionein-like protein in human erythrocytes. Church, H.J., Day, J.P., Braithwaite, R.A., Brown, S.S. J. Inorg. Biochem. (1993) [Pubmed]
  20. Cadmium-binding proteins in human organs. Sato, M., Takizawa, Y. Toxicol. Lett. (1982) [Pubmed]
  21. Cadmium and copper metallothioneins in the American lobster, Homarus americanus. Engel, D.W., Brouwer, M. Environ. Health Perspect. (1986) [Pubmed]
  22. RNA expression patterns of a type 2 metallothionein-like gene from rice. Hsieh, H.M., Liu, W.K., Chang, A., Huang, P.C. Plant Mol. Biol. (1996) [Pubmed]
  23. Metal ion resistance in fungi: molecular mechanisms and their regulated expression. Mehra, R.K., Winge, D.R. J. Cell. Biochem. (1991) [Pubmed]
  24. Cloning and characterization of five cDNAs for genes differentially expressed during fruit development of kiwifruit (Actinidia deliciosa var. deliciosa). Ledger, S.E., Gardner, R.C. Plant Mol. Biol. (1994) [Pubmed]
  25. Isolation and characterization of cDNAs for differentially accumulated transcripts between mesophyll cells and bundle sheath strands of maize leaves. Furumoto, T., Hata, S., Izui, K. Plant Cell Physiol. (2000) [Pubmed]
  26. Hippocampal zinc thionein and pyridoxal phosphate modulate synaptic functions. Ebadi, M., Murrin, L.C., Pfeiffer, R.F. Ann. N. Y. Acad. Sci. (1990) [Pubmed]
  27. Molecular cloning of two metallothionein-like protein genes with differential expression patterns from sweet potato (Ipomoea batatas) leaves. Chen, H.J., Hou, W.C., Yang, C.Y., Huang, D.J., Liu, J.S., Lin, Y.H. J. Plant Physiol. (2003) [Pubmed]
  28. Type 2 rice metallothionein-like gene has two introns. Chen, W.M., Hsieh, H.M., Huang, P.C. DNA Seq. (1998) [Pubmed]
  29. The enhanced induction of metallothionein by zinc, its half-life in the marine fish Pleuronectes platessa, and the influence of stress factors on metallothionein levels. Overnell, J., McIntosh, R., Fletcher, T.C. Experientia (1987) [Pubmed]
 
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