Gene Review:
HOOK1 - hook microtubule-tethering protein 1
Homo sapiens
Synonyms:
HK1, Protein Hook homolog 1, h-hook1, hHK1
- The Hook1 gene is non-functional in the abnormal spermatozoon head shape (azh) mutant mouse. Mendoza-Lujambio, I., Burfeind, P., Dixkens, C., Meinhardt, A., Hoyer-Fender, S., Engel, W., Neesen, J. Hum. Mol. Genet. (2002)
- Transgenic coexpression of v-Ha-ras and transforming growth factor alpha increases epidermal hyperproliferation and tumorigenesis and predisposes to malignant conversion via endogenous c-Ha-ras activation. Wang, X.J., Greenhalgh, D.A., Roop, D.R. Mol. Carcinog. (2000)
- Adhesion and cell-surface-hydrophobicity of sequentially isolated genetic isotypes of Candida albicans in an HIV-infected Southern Chinese cohort. Samaranayake, Y.H., Samaranayake, L.P., Yau, J.Y., Ellepola, A.N., Anil, S., Yeung, K.W. Mycoses (2003)
- T-cell developmental blockage by tachykinin antagonists and the role of hemokinin 1 in T lymphopoiesis. Zhang, Y., Paige, C.J. Blood (2003)
- Modulation of an inactivating human cardiac K+ channel by protein kinase C. Murray, K.T., Fahrig, S.A., Deal, K.K., Po, S.S., Hu, N.N., Snyders, D.J., Tamkun, M.M., Bennett, P.B. Circ. Res. (1994)
- Differentiation-specific expression of human keratin 1 is mediated by a composite AP-1/steroid hormone element. Lu, B., Rothnagel, J.A., Longley, M.A., Tsai, S.Y., Roop, D.R. J. Biol. Chem. (1994)
- Overexpression of Sonic Hedgehog suppresses embryonic hair follicle morphogenesis. Ellis, T., Smyth, I., Riley, E., Bowles, J., Adolphe, C., Rothnagel, J.A., Wicking, C., Wainwright, B.J. Dev. Biol. (2003)
- Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma. Kwong, J., Lo, K.W., Chow, L.S., Chan, F.L., To, K.F., Huang, D.P. Int. J. Cancer (2005)
- Regional mapping of the locus for hexokinase-1 (HK1) to 10p11 equals to q23 by gene dosage in human fibroblasts. Gitelman, B.J., Simpson, N.E. Hum. Genet. (1982)
- Anti-tumor effect of angiogenesis inhibitor TNP-470 on the human nasopharyngeal carcinoma cell line NPC/HK1. Qian, C.N., Min, H.Q., Lin, H.L., Feng, G.K., Ye, Y.L., Wang, L.G., Kuang, Z.J. Oncology (1999)
- Hypericin-mediated photodynamic therapy induces lipid peroxidation and necrosis in nasopharyngeal cancer. Du, H.Y., Olivo, M., Tan, B.K., Bay, B.H. Int. J. Oncol. (2003)
- Modulation of Matrix metalloproteinase-1 in nasopharyngeal cancer cells by photoactivation of hypericin. Du, H., Olivo, M., Mahendran, R., Bay, B.H. Int. J. Oncol. (2004)
- Tachykinins and tachykinin receptors in human uterus. Patak, E., Candenas, M.L., Pennefather, J.N., Ziccone, S., Lilley, A., Martín, J.D., Flores, C., Mantecón, A.G., Story, M.E., Pinto, F.M. Br. J. Pharmacol. (2003)
- Evidence of gene dosage effect for HK 1 in the red cells of a patient with trisomy 10pter leads to p13. Dallapiccola, B., Serena Lungarotti, M., Magnani, M., Dacha, M. Ann. Genet. (1981)
- Quercetin-induced growth inhibition and cell death in nasopharyngeal carcinoma cells are associated with increase in Bad and hypophosphorylated retinoblastoma expressions. Ong, C.S., Tran, E., Nguyen, T.T., Ong, C.K., Lee, S.K., Lee, J.J., Ng, C.P., Leong, C., Huynh, H. Oncol. Rep. (2004)
- Antitumor effect and enhancement of cytotoxic drug activity by cetuximab in nasopharyngeal carcinoma cells. Sung, F.L., Poon, T.C., Hui, E.P., Ma, B.B., Liong, E., To, K.F., Huang, D.P., Chan, A.T. In Vivo (2005)
- Characterization of human genomic yeast artificial chromosome inserts containing hexokinase 1 coding information on chromosome 10. Gelb, B.D., Worley, K.C., Griffin, L.D., Adams, V., Chinault, A.C., McCabe, E.R. Biochem. Med. Metab. Biol. (1992)