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MeSH Review

Infertility, Male

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Disease relevance of Infertility, Male


Psychiatry related information on Infertility, Male

  • IVF-seeking patients generally desire privacy, even total secrecy, when pursuing these treatments, due to cultural issues of stigmatization, particularly regarding male infertility [6].

High impact information on Infertility, Male


Chemical compound and disease context of Infertility, Male


Biological context of Infertility, Male


Anatomical context of Infertility, Male


Gene context of Infertility, Male


Analytical, diagnostic and therapeutic context of Infertility, Male


  1. Male sterility of the mouse t-complex is due to homozygosity of the distorter genes. Lyon, M.F. Cell (1986) [Pubmed]
  2. Adult-onset idiopathic hypogonadotropic hypogonadism--a treatable form of male infertility. Nachtigall, L.B., Boepple, P.A., Pralong, F.P., Crowley, W.F. N. Engl. J. Med. (1997) [Pubmed]
  3. Sterility of Drosophila with mutations in the Bloom syndrome gene--complementation by Ku70. Kusano, K., Johnson-Schlitz, D.M., Engels, W.R. Science (2001) [Pubmed]
  4. Linkage between male infertility and trinucleotide repeat expansion in the androgen-receptor gene. Dowsing, A.T., Yong, E.L., Clark, M., McLachlan, R.I., de Kretser, D.M., Trounson, A.O. Lancet (1999) [Pubmed]
  5. Genetically engineered cytoplasmic male sterility. Chase, C.D. Trends Plant Sci. (2006) [Pubmed]
  6. Privacy, privatization, and the politics of patronage: ethnographic challenges to penetrating the secret world of Middle Eastern, hospital-based in vitro fertilization. Inhorn, M.C. Social science & medicine (1982) (2004) [Pubmed]
  7. Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility. Rovio, A.T., Marchington, D.R., Donat, S., Schuppe, H.C., Abel, J., Fritsche, E., Elliott, D.J., Laippala, P., Ahola, A.L., McNay, D., Harrison, R.F., Hughes, B., Barrett, T., Bailey, D.M., Mehmet, D., Jequier, A.M., Hargreave, T.B., Kao, S.H., Cummins, J.M., Barton, D.E., Cooke, H.J., Wei, Y.H., Wichmann, L., Poulton, J., Jacobs, H.T. Nat. Genet. (2001) [Pubmed]
  8. Homozygous methylenetetrahydrofolate reductase C677T mutation and male infertility. Bezold, G., Lange, M., Peter, R.U. N. Engl. J. Med. (2001) [Pubmed]
  9. Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4. Wu, J.Y., Ribar, T.J., Cummings, D.E., Burton, K.A., McKnight, G.S., Means, A.R. Nat. Genet. (2000) [Pubmed]
  10. Role of Ahch in gonadal development and gametogenesis. Yu, R.N., Ito, M., Saunders, T.L., Camper, S.A., Jameson, J.L. Nat. Genet. (1998) [Pubmed]
  11. Male infertility due to sulphasalazine. Toth, A. Lancet (1979) [Pubmed]
  12. Clomiphene in treatment of male infertility due to isolated follicle-stimulating-hormone deficiency. McConnon, J., Killinger, D., Gracey, W., Ghany, F. Lancet (1979) [Pubmed]
  13. Reversal of male infertility on changing treatment from sulphasalazine to 5-aminosalicylic acid. Cann, P.A., Holdsworth, C.D. Lancet (1984) [Pubmed]
  14. Treatment of immune male infertility with methylprednisolone. Shulman, S. Lancet (1976) [Pubmed]
  15. Levamisole treatment in male infertility due to spermagglutinins. Luisi, M., Gasperi, M., Franchi, F., D'Acunto, A., Tauro, C.S. Lancet (1982) [Pubmed]
  16. Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification. Roest, H.P., van Klaveren, J., de Wit, J., van Gurp, C.G., Koken, M.H., Vermey, M., van Roijen, J.H., Hoogerbrugge, J.W., Vreeburg, J.T., Baarends, W.M., Bootsma, D., Grootegoed, J.A., Hoeijmakers, J.H. Cell (1996) [Pubmed]
  17. Inactivation of a sperm motility gene by insertion of an epidermal growth factor receptor transgene whose product is overexpressed and compartmentalized during spermatogenesis. Merlino, G.T., Stahle, C., Jhappan, C., Linton, R., Mahon, K.A., Willingham, M.C. Genes Dev. (1991) [Pubmed]
  18. Disruption of the protein C inhibitor gene results in impaired spermatogenesis and male infertility. Uhrin, P., Dewerchin, M., Hilpert, M., Chrenek, P., Schöfer, C., Zechmeister-Machhart, M., Krönke, G., Vales, A., Carmeliet, P., Binder, B.R., Geiger, M. J. Clin. Invest. (2000) [Pubmed]
  19. Cell type-specific loss of atp6 RNA editing in cytoplasmic male sterile Sorghum bicolor. Howad, W., Kempken, F. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  20. Identification of a testis-specific gene from the mouse t-complex next to a CpG-rich island. Rappold, G.A., Stubbs, L., Labeit, S., Crkvenjakov, R.B., Lehrach, H. EMBO J. (1987) [Pubmed]
  21. The mouse juvenile spermatogonial depletion (jsd) phenotype is due to a mutation in the X-derived retrogene, mUtp14b. Rohozinski, J., Bishop, C.E. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  22. Identification and characterization of SSTK, a serine/threonine protein kinase essential for male fertility. Spiridonov, N.A., Wong, L., Zerfas, P.M., Starost, M.F., Pack, S.D., Paweletz, C.P., Johnson, G.R. Mol. Cell. Biol. (2005) [Pubmed]
  23. Loss of TSLC1 causes male infertility due to a defect at the spermatid stage of spermatogenesis. van der Weyden, L., Arends, M.J., Chausiaux, O.E., Ellis, P.J., Lange, U.C., Surani, M.A., Affara, N., Murakami, Y., Adams, D.J., Bradley, A. Mol. Cell. Biol. (2006) [Pubmed]
  24. Nasal epithelial ion transport and genetic analysis of infertile men with congenital bilateral absence of the vas deferens. Osborne, L.R., Lynch, M., Middleton, P.G., Alton, E.W., Geddes, D.M., Pryor, J.P., Hodson, M.E., Santis, G.K. Hum. Mol. Genet. (1993) [Pubmed]
  25. Absence of the prion protein homologue Doppel causes male sterility. Behrens, A., Genoud, N., Naumann, H., Rülicke, T., Janett, F., Heppner, F.L., Ledermann, B., Aguzzi, A. EMBO J. (2002) [Pubmed]
  26. Deletion of the Parkin coregulated gene causes male sterility in the quaking(viable) mouse mutant. Lorenzetti, D., Bishop, C.E., Justice, M.J. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  27. Six5 is required for spermatogenic cell survival and spermiogenesis. Sarkar, P.S., Paul, S., Han, J., Reddy, S. Hum. Mol. Genet. (2004) [Pubmed]
  28. The Hook1 gene is non-functional in the abnormal spermatozoon head shape (azh) mutant mouse. Mendoza-Lujambio, I., Burfeind, P., Dixkens, C., Meinhardt, A., Hoyer-Fender, S., Engel, W., Neesen, J. Hum. Mol. Genet. (2002) [Pubmed]
  29. Infertility associated with incomplete spermatogenic arrest and oligozoospermia in Egr4-deficient mice. Tourtellotte, W.G., Nagarajan, R., Auyeung, A., Mueller, C., Milbrandt, J. Development (1999) [Pubmed]
  30. Male infertility and variation in CAG repeat length in the androgen receptor gene: a meta-analysis. Davis-Dao, C.A., Tuazon, E.D., Sokol, R.Z., Cortessis, V.K. J. Clin. Endocrinol. Metab. (2007) [Pubmed]
  31. The Y deletion gr/gr and susceptibility to testicular germ cell tumor. Nathanson, K.L., Kanetsky, P.A., Hawes, R., Vaughn, D.J., Letrero, R., Tucker, K., Friedlander, M., Phillips, K.A., Hogg, D., Jewett, M.A., Lohynska, R., Daugaard, G., Richard, S., Chompret, A., Bonaïti-Pellié, C., Heidenreich, A., Olah, E., Geczi, L., Bodrogi, I., Ormiston, W.J., Daly, P.A., Oosterhuis, J.W., Gillis, A.J., Looijenga, L.H., Guilford, P., Fosså, S.D., Heimdal, K., Tjulandin, S.A., Liubchenko, L., Stoll, H., Weber, W., Rudd, M., Huddart, R., Crockford, G.P., Forman, D., Oliver, D.T., Einhorn, L., Weber, B.L., Kramer, J., McMaster, M., Greene, M.H., Pike, M., Cortessis, V., Chen, C., Schwartz, S.M., Bishop, D.T., Easton, D.F., Stratton, M.R., Rapley, E.A. Am. J. Hum. Genet. (2005) [Pubmed]
  32. Genes in the first and fourth inversions of the mouse t complex synergistically mediate sperm capacitation and interactions with the oocyte. Redkar, A.A., Si, Y., Twine, S.N., Pilder, S.H., Olds-Clarke, P. Dev. Biol. (2000) [Pubmed]
  33. Ethanol-induced male infertility: impairment of spermatozoa. Anderson, R.A., Willis, B.R., Oswald, C., Zaneveld, L.J. J. Pharmacol. Exp. Ther. (1983) [Pubmed]
  34. The gene CSTF2T, encoding the human variant CstF-64 polyadenylation protein tauCstF-64, lacks introns and may be associated with male sterility. Dass, B., McDaniel, L., Schultz, R.A., Attaya, E., MacDonald, C.C. Genomics (2002) [Pubmed]
  35. Decreased protamine-1 transcript levels in testes from infertile men. Steger, K., Fink, L., Failing, K., Bohle, R.M., Kliesch, S., Weidner, W., Bergmann, M. Mol. Hum. Reprod. (2003) [Pubmed]
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