Gene Review:
PKNOX1 - PBX/knotted 1 homeobox 1
Homo sapiens
Synonyms:
Homeobox protein PKNOX1, Homeobox protein PREP-1, PBX/knotted homeobox 1, PREP1, pkonx1c
- Cloning of a novel homeobox-containing gene, PKNOX1, and mapping to human chromosome 21q22.3. Chen, H., Rossier, C., Nakamura, Y., Lynn, A., Chakravarti, A., Antonarakis, S.E. Genomics (1997)
- Overexpression of PREP-1 in F9 teratocarcinoma cells leads to a functionally relevant increase of PBX-2 by preventing its degradation. Longobardi, E., Blasi, F. J. Biol. Chem. (2003)
- The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity. Berthelsen, J., Zappavigna, V., Ferretti, E., Mavilio, F., Blasi, F. EMBO J. (1998)
- Prep1, a novel functional partner of Pbx proteins. Berthelsen, J., Zappavigna, V., Mavilio, F., Blasi, F. EMBO J. (1998)
- MEIS C termini harbor transcriptional activation domains that respond to cell signaling. Huang, H., Rastegar, M., Bodner, C., Goh, S.L., Rambaldi, I., Featherstone, M. J. Biol. Chem. (2005)
- Overexpression of FABP7 in Down syndrome fetal brains is associated with PKNOX1 gene-dosage imbalance. Sánchez-Font, M.F., Bosch-Comas, A., Gonzàlez-Duarte, R., Marfany, G. Nucleic Acids Res. (2003)
- PREP1, MEIS1 homolog protein, regulates PF4 gene expression. Okada, Y., Matsuura, E., Nagai, R., Sato, T., Watanabe, A., Morita, I., Doi, T. Biochem. Biophys. Res. Commun. (2003)
- Changing homeodomain residues 2 and 3 of Hoxa1 alters its activity in a cell-type and enhancer dependent manner. Remacle, S., Shaw-Jackson, C., Matis, C., Lampe, X., Picard, J., Rezsöhazy, R. Nucleic Acids Res. (2002)
- The HOXC13-controlled expression of early hair keratin genes in the human hair follicle does not involve TALE proteins MEIS and PREP as cofactors. Jave-Suárez, L.F., Schweizer, J. Arch. Dermatol. Res. (2006)
- Polymorphic variations in the expression of the chemical detoxifying UDP glucuronosyltransferases. Mackenzie, P.I., Gregory, P.A., Lewinsky, R.H., Yasmin, S.N., Height, T., McKinnon, R.A., Gardner-Stephen, D.A. Toxicol. Appl. Pharmacol. (2005)
- Prospective, randomized, controlled comparison of the use of polyethylene glycol electrolyte lavage solution in four-liter versus two-liter volumes and pretreatment with either magnesium citrate or bisacodyl for colonoscopy preparation. Sharma, V.K., Chockalingham, S.K., Ugheoke, E.A., Kapur, A., Ling, P.H., Vasudeva, R., Howden, C.W. Gastrointest. Endosc. (1998)
- Extraction of benzoylecgonine from urine specimens with Cerex Polycrom Clin II solid-phase extraction columns and the Speedisk Pressure Processor. Kuhnle, J.A., Churley, M., Kawasaki, S.Y., Lyons, T.P., Bruins, M.R. Journal of analytical toxicology. (2001)
- Reflex high-risk human papilloma virus DNA test is useful in the triage of women with atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion. Wu, H.H., Allen, S.L., Kirkpatrick, J.L., Elsheikh, T.M. Diagn. Cytopathol. (2006)
- Novel alternative PBX3 isoforms in leukemia cells with distinct interaction specificities. Milech, N., Kees, U.R., Watt, P.M. Genes Chromosomes Cancer (2001)
- Cooperative interactions between PBX, PREP, and HOX proteins modulate the activity of the alpha 2(V) collagen (COL5A2) promoter. Penkov, D., Tanaka, S., Di Rocco, G., Berthelsen, J., Blasi, F., Ramirez, F. J. Biol. Chem. (2000)
- Identification and characterization of human PKNOX2, a novel homeobox-containing gene. Imoto, I., Sonoda, I., Yuki, Y., Inazawa, J. Biochem. Biophys. Res. Commun. (2001)
- The homeodomain Pbx2-Prep1 complex modulates hepatocyte nuclear factor 1alpha-mediated activation of the UDP-glucuronosyltransferase 2B17 gene. Gregory, P.A., Mackenzie, P.I. Mol. Pharmacol. (2002)
- From testicular biopsy to human embryo. Jezek, D., Knezević, N., Kalanj-Bognar, S., Vukelić, Z., Krhen, I. Verhandlungen der Deutschen Gesellschaft für Pathologie. (2004)