Gene Review:
Map3k14 - mitogen-activated protein kinase kinase...
Mus musculus
Synonyms:
Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, Nik, Serine/threonine-protein kinase NIK, aly
- Host resistance against Listeria monocytogenes is reciprocal during the course of infection in alymphoplastic aly mutant mice. Nishikawa, S., Nakane, A. Cell. Immunol. (1998)
- On the key role of secondary lymphoid organs in antiviral immune responses studied in alymphoplastic (aly/aly) and spleenless (Hox11(-)/-) mutant mice. Karrer, U., Althage, A., Odermatt, B., Roberts, C.W., Korsmeyer, S.J., Miyawaki, S., Hengartner, H., Zinkernagel, R.M. J. Exp. Med. (1997)
- aly/aly mice: a unique model of biliary disease. Tsuneyama, K., Kono, N., Hoso, M., Sugahara, H., Yoshida, K., Katayanagi, K., Gershwin, M.E., Saito, K., Nakanuma, Y. Hepatology (1998)
- A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice. Miyawaki, S., Nakamura, Y., Suzuka, H., Koba, M., Yasumizu, R., Ikehara, S., Shibata, Y. Eur. J. Immunol. (1994)
- An accessory role of TCRgammadelta (+) cells in the exacerbation of inflammatory bowel disease in TCRalpha mutant mice. Kawaguchi-Miyashita, M., Shimada , S., Kurosu, H., Kato-Nagaoka, N., Matsuoka, Y., Ohwaki, M., Ishikawa, H., Nanno, M. Eur. J. Immunol. (2001)
- Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase. Shinkura, R., Kitada, K., Matsuda, F., Tashiro, K., Ikuta, K., Suzuki, M., Kogishi, K., Serikawa, T., Honjo, T. Nat. Genet. (1999)
- Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR. Boehm, T., Scheu, S., Pfeffer, K., Bleul, C.C. J. Exp. Med. (2003)
- NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells. Elewaut, D., Shaikh, R.B., Hammond, K.J., De Winter, H., Leishman, A.J., Sidobre, S., Turovskaya, O., Prigozy, T.I., Ma, L., Banks, T.A., Lo, D., Ware, C.F., Cheroutre, H., Kronenberg, M. J. Exp. Med. (2003)
- NF-(kappa)B-inducing kinase controls lymphocyte and osteoclast activities in inflammatory arthritis. Aya, K., Alhawagri, M., Hagen-Stapleton, A., Kitaura, H., Kanagawa, O., Veis Novack, D. J. Clin. Invest. (2005)
- Role of T and NK cells and IL7/IL7r interactions during neonatal maturation of lymph nodes. Coles, M.C., Veiga-Fernandes, H., Foster, K.E., Norton, T., Pagakis, S.N., Seddon, B., Kioussis, D. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Immunodeficiency of alymphoplasia mice (aly/aly) in vivo: structural defect of secondary lymphoid organs and functional B cell defect. Karrer, U., Althage, A., Odermatt, B., Hengartner, H., Zinkernagel, R.M. Eur. J. Immunol. (2000)
- The donor splice site mutation in NFkappaB-inducing kinase of alymphoplasia (aly/aly) mice. Macpherson, A.J., Uhr, T. Immunogenetics (2003)
- The effect of a novel immunosuppressant, FTY720, in mice without secondary lymphoid organs. Sugito, K., Koshinaga, T., Inoue, M., Ikeda, T., Hagiwara, N., Fukuzawa, M. Surgery today. (2005)
- Essential role of NF-kappa B-inducing kinase in T cell activation through the TCR/CD3 pathway. Matsumoto, M., Yamada, T., Yoshinaga, S.K., Boone, T., Horan, T., Fujita, S., Li, Y., Mitani, T. J. Immunol. (2002)
- Analysis of expression of lymphocyte homing-related adhesion molecules in ALY mice deficient in lymph nodes and Peyer's patches. Koike, R., Watanabe, T., Satoh, H., Hee, C.S., Kitada, K., Kuramoto, T., Serikawa, T., Miyawaki, S., Miyasaka, M. Cell. Immunol. (1997)
- Thymic epithelial cells responsible for impaired generation of NK-T thymocytes in Alymphoplasia mutant mice. Konishi, J., Iwabuchi, K., Iwabuchi, C., Ato, M., Nagata , J.I., Onoé, K., Nakagawa, K.I., Kasai, M., Ogasawara, K., Kawakami, K., Onoé, K. Cell. Immunol. (2000)
- The splenic marginal zone is absent in alymphoplastic aly mutant mice. Koike, R., Nishimura, T., Yasumizu, R., Tanaka, H., Hataba, Y., Hataba, Y., Watanabe, T., Miyawaki, S., Miyasaka, M. Eur. J. Immunol. (1996)
- Analysis of the mode of action of a novel immunosuppressant FTY720 in mice. Luo, Z.J., Tanaka, T., Kimura, F., Miyasaka, M. Immunopharmacology (1999)
- Dysregulation of interleukin-10 and interleukin-12 are involved in the reduced host resistance to Listeria monocytogenes infection in alymphoplastic aly mutant mice. Hasegawa, S., Miura, T., Sasaki, S., Madarame, H., Nakane, A. FEMS Immunol. Med. Microbiol. (2002)