Gene Review:
Irf7 - interferon regulatory factor 7
Mus musculus
Synonyms:
IRF-7, Interferon regulatory factor 7
- Differential regulation of interferon regulatory factor (IRF)-7 and IRF-9 gene expression in the central nervous system during viral infection. Ousman, S.S., Wang, J., Campbell, I.L. J. Virol. (2005)
- Interferon regulatory factor 7 is associated with Epstein-Barr virus-transformed central nervous system lymphoma and has oncogenic properties. Zhang, L., Zhang, J., Lambert, Q., Der, C.J., Del Valle, L., Miklossy, J., Khalili, K., Zhou, Y., Pagano, J.S. J. Virol. (2004)
- Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Sato, M., Suemori, H., Hata, N., Asagiri, M., Ogasawara, K., Nakao, K., Nakaya, T., Katsuki, M., Noguchi, S., Tanaka, N., Taniguchi, T. Immunity (2000)
- Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction. Uematsu, S., Sato, S., Yamamoto, M., Hirotani, T., Kato, H., Takeshita, F., Matsuda, M., Coban, C., Ishii, K.J., Kawai, T., Takeuchi, O., Akira, S. J. Exp. Med. (2005)
- Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation. Okabe, Y., Kawane, K., Akira, S., Taniguchi, T., Nagata, S. J. Exp. Med. (2005)
- Negative regulation of Toll-like-receptor signaling by IRF-4. Negishi, H., Ohba, Y., Yanai, H., Takaoka, A., Honma, K., Yui, K., Matsuyama, T., Taniguchi, T., Honda, K. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter. Qing, J., Liu, C., Choy, L., Wu, R.Y., Pagano, J.S., Derynck, R. Mol. Cell. Biol. (2004)
- Heightened Interferon-{alpha}/beta Response Causes Myeloid Cell Dysfunction and Promotes T1D Pathogenesis in NOD Mice. Peng, R.H., Paek, E., Xia, C.Q., Tennyson, N., Clare-Salzler, M.J. Ann. N. Y. Acad. Sci. (2006)
- IRF-7 is the master regulator of type-I interferon-dependent immune responses. Honda, K., Yanai, H., Negishi, H., Asagiri, M., Sato, M., Mizutani, T., Shimada, N., Ohba, Y., Takaoka, A., Yoshida, N., Taniguchi, T. Nature (2005)
- Regulatory serine residues mediate phosphorylation-dependent and phosphorylation-independent activation of interferon regulatory factor 7. Caillaud, A., Hovanessian, A.G., Levy, D.E., Marié, I.J. J. Biol. Chem. (2005)
- Impairment of interferon-induced IRF-7 gene expression due to inhibition of ISGF3 formation by trichostatin A. Génin, P., Morin, P., Civas, A. J. Virol. (2003)
- Tissue-specific positive feedback requirements for production of type I interferon following virus infection. Prakash, A., Smith, E., Lee, C.K., Levy, D.E. J. Biol. Chem. (2005)
- Regulation of DNA-raised immune responses by cotransfected interferon regulatory factors. Sasaki, S., Amara, R.R., Yeow, W.S., Pitha, P.M., Robinson, H.L. J. Virol. (2002)
- Essential role of IRF-3 in lipopolysaccharide-induced interferon-beta gene expression and endotoxin shock. Sakaguchi, S., Negishi, H., Asagiri, M., Nakajima, C., Mizutani, T., Takaoka, A., Honda, K., Taniguchi, T. Biochem. Biophys. Res. Commun. (2003)
- Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7. Sato, M., Hata, N., Asagiri, M., Nakaya, T., Taniguchi, T., Tanaka, N. FEBS Lett. (1998)
- Candidate genes associated with tumor regression mediated by intratumoral IL-12 electroporation gene therapy. Li, S., Xia, X., Mellieon, F.M., Liu, J., Steele, S. Mol. Ther. (2004)
- Super-activated interferon-regulatory factors can enhance plasmid immunization. Bramson, J.L., Dayball, K., Hall, J.R., Millar, J.B., Miller, M., Wan, Y.H., Lin, R., Hiscott, J. Vaccine (2003)