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Gene Review

UGP1  -  UDP-glucose pyrophosphorylase 1

Homo sapiens

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Disease relevance of UGP1


High impact information on UGP1


Biological context of UGP1


Associations of UGP1 with chemical compounds


Physical interactions of UGP1


Other interactions of UGP1


Analytical, diagnostic and therapeutic context of UGP1


  1. Role of nuclear glycogen synthase and cytoplasmic UDP glucose pyrophosphorylase in the biosynthesis of nuclear glycogen in HD33 Ehrlich-Lettré ascites tumor cells. Granzow, C., Kopun, M., Zimmermann, H.P. J. Cell Biol. (1981) [Pubmed]
  2. Molecular cloning of the Leishmania major UDP-glucose pyrophosphorylase, functional characterization, and ligand binding analyses using NMR spectroscopy. Lamerz, A.C., Haselhorst, T., Bergfeld, A.K., von Itzstein, M., Gerardy-Schahn, R. J. Biol. Chem. (2006) [Pubmed]
  3. Effects of insulin and transgenic overexpression of UDP-glucose pyrophosphorylase on UDP-glucose and glycogen accumulation in skeletal muscle fibers. Reynolds, T.H., Pak, Y., Harris, T.E., Manchester, J., Barrett, E.J., Lawrence, J.C. J. Biol. Chem. (2005) [Pubmed]
  4. Unidirectional steady state rates of central metabolism enzymes measured simultaneously in a living plant tissue. Roscher, A., Emsley, L., Raymond, P., Roby, C. J. Biol. Chem. (1998) [Pubmed]
  5. Direct demonstration of mechanically induced release of cellular UTP and its implication for uridine nucleotide receptor activation. Lazarowski, E.R., Homolya, L., Boucher, R.C., Harden, T.K. J. Biol. Chem. (1997) [Pubmed]
  6. Assignment of a molecular form of UDP glucose pyrophosphorylase (UGPP2) to chromosome 2 in man. Shows, T.B., Brown, J.A., Goggin, A.P., Haley, L.L., Byers, M.G., Eddy, R.L. Cytogenet. Cell Genet. (1978) [Pubmed]
  7. UDP-glucose pyrophosphorylase: up-regulation in hypertrophic cartilage and role in hyaluronan synthesis. Magee, C., Nurminskaya, M., Linsenmayer, T.F. Biochem. J. (2001) [Pubmed]
  8. Pyrophosphorylases in potato. V. Allelic polymorphism of UDP-glucose pyrophosphorylase in potato cultivars and its association with tuber resistance to sweetening in the cold. Sowokinos, J.R., Thomas, C., Burrell, M.M. Plant Physiol. (1997) [Pubmed]
  9. Analysis of the expression of potato uridinediphosphate-glucose pyrophosphorylase and its inhibition by antisense RNA. Zrenner, R., Willmitzer, L., Sonnewald, U. Planta (1993) [Pubmed]
  10. Organization and transcription of the gene encoding potato UDP-glucose pyrophosphorylase. Borovkov, A.Y., McClean, P.E., Secor, G.A. Gene (1997) [Pubmed]
  11. UDP-glucose pyrophosphorylase. Stereochemical course of the reaction of glucose 1-phosphate with uridine-5'[1-thiotriphosphate]. Sheu, K.F., Frey, P.A. J. Biol. Chem. (1978) [Pubmed]
  12. Analysis of the compartmentation of glycolytic intermediates, nucleotides, sugars, organic acids, amino acids, and sugar alcohols in potato tubers using a nonaqueous fractionation method. Farré, E.M., Tiessen, A., Roessner, U., Geigenberger, P., Trethewey, R.N., Willmitzer, L. Plant Physiol. (2001) [Pubmed]
  13. Identification of lysyl residues located at the substrate-binding site in UDP-glucose pyrophosphorylase from potato tuber: affinity labeling with uridine di- and triphosphopyridoxals. Kazuta, Y., Omura, Y., Tagaya, M., Nakano, K., Fukui, T. Biochemistry (1991) [Pubmed]
  14. Glucose and lactate metabolism by Actinomyces naeslundii. Takahashi, N., Yamada, T. Crit. Rev. Oral Biol. Med. (1999) [Pubmed]
  15. Probing the pyrophosphate-binding site in potato tuber UDP-glucose pyrophosphorylase with pyridoxal diphosphate. Kazuta, Y., Tagaya, M., Tanizawa, K., Fukui, T. Protein Sci. (1993) [Pubmed]
  16. Investigation of the UDP-glucose dehydrogenase reaction for a coupled assay of UDP-glucose pyrophosphorylase activities. Elling, L., Kula, M.R. Biotechnol. Appl. Biochem. (1991) [Pubmed]
  17. Proteomic analyses of somatic and zygotic embryos of Cyclamen persicum Mill. reveal new insights into seed and germination physiology. Winkelmann, T., Heintz, D., Van Dorsselaer, A., Serek, M., Braun, H.P. Planta (2006) [Pubmed]
  18. Potato guard cells respond to drying soil by a complex change in the expression of genes related to carbon metabolism and turgor regulation. Kopka, J., Provart, N.J., Müller-Röber, B. Plant J. (1997) [Pubmed]
  19. Isolation and assignment of the UDP-glucose pyrophosphorylase gene (UGP2) to porcine chromosome 3q21-->q22 by FISH and by analysis of somatic cell and radiation hybrid panels. Looft, C., Paul, S., Thomsen, P.D., Yerle, M., Brenig, B., Kalm, E. Cytogenet. Cell Genet. (2000) [Pubmed]
  20. Exploring the active site in UDP-glucose pyrophosphorylase by affinity labelling and site-directed mutagenesis. Fukui, T., Kazuta, Y., Katsube, T., Tagaya, M., Tanizawa, K. Biotechnol. Appl. Biochem. (1993) [Pubmed]
  21. Molecular cloning and sequence variation of UDP-glucose pyrophosphorylase cDNAs from potatoes sensitive and resistant to cold sweetening. Sowokinos, J.R., Vigdorovich, V., Abrahamsen, M. J. Plant Physiol. (2004) [Pubmed]
  22. An HPLC method for the assay of UDP-glucose pyrophosphorylase and UDP-glucose-4-epimerase in Solieria chordalis (Rhodophyceae). Goulard, F., Diouris, M., Deslandes, E., Floc'h, J.Y. Phytochemical analysis : PCA. (2001) [Pubmed]
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