Gene Review:
RPS6KA5 - ribosomal protein S6 kinase, 90kDa,...
Homo sapiens
Synonyms:
90 kDa ribosomal protein S6 kinase 5, MSK1, MSPK1, Nuclear mitogen-and stress-activated protein kinase 1, RLPK, ...
- Mitogen- and stress-activated protein kinase 1 is critical for interleukin-1-induced, CREB-mediated, c-fos gene expression in keratinocytes. Schiller, M., Böhm, M., Dennler, S., Ehrchen, J.M., Mauviel, A. Oncogene (2006)
- Attenuation of mitogen- and stress-activated protein kinase-1-driven nuclear factor-kappaB gene expression by soy isoflavones does not require estrogenic activity. Vanden Berghe, W., Dijsselbloem, N., Vermeulen, L., Ndlovu, N., Boone, E., Haegeman, G. Cancer Res. (2006)
- Activation of JNK1, RSK2, and MSK1 is involved in serine 112 phosphorylation of Bad by ultraviolet B radiation. She, Q.B., Ma, W.Y., Zhong, S., Dong, Z. J. Biol. Chem. (2002)
- Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-inflammatory cytokines. Funding, A.T., Johansen, C., Kragballe, K., Otkjaer, K., Jensen, U.B., Madsen, M.W., Fjording, M.S., Finnemann, J., Skak-Nielsen, T., Paludan, S.R., Iversen, L. J. Invest. Dermatol. (2006)
- Activation of the mitogen- and stress-activated kinase 1 by arsenic trioxide. Kannan-Thulasiraman, P., Katsoulidis, E., Tallman, M.S., Arthur, J.S., Platanias, L.C. J. Biol. Chem. (2006)
- Ca(2+)-Stimulated Adenylyl Cyclases Regulate ERK-Dependent Activation of MSK1 during Fear Conditioning. Sindreu, C.B., Scheiner, Z.S., Storm, D.R. Neuron (2007)
- Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1). Vermeulen, L., De Wilde, G., Van Damme, P., Vanden Berghe, W., Haegeman, G. EMBO J. (2003)
- Selective repression of low-density lipoprotein receptor expression by SP600125: coupling of histone H3-Ser10 phosphorylation and Sp1 occupancy. Huang, W., Batra, S., Korrapati, S., Mishra, V., Mehta, K.D. Mol. Cell. Biol. (2006)
- Chromatin modification of the trefoil factor 1 gene in human breast cancer cells by the Ras/mitogen-activated protein kinase pathway. Espino, P.S., Li, L., He, S., Yu, J., Davie, J.R. Cancer Res. (2006)
- Assignment of a member of the ribosomal protein S6 kinase family, RPS6KA5, to human chromosome 14q31-->q32.1 by radiation hybrid mapping. Jiang, C., Yu, L., Tu, Q., Zhao, Y., Zhang, H., Zhao, S. Cytogenet. Cell Genet. (1999)
- Cloning and characterization of RLPK, a novel RSK-related protein kinase. New, L., Zhao, M., Li, Y., Bassett, W.W., Feng, Y., Ludwig, S., Padova, F.D., Gram, H., Han, J. J. Biol. Chem. (1999)
- The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling. Dunn, K.L., Espino, P.S., Drobic, B., He, S., Davie, J.R. Biochem. Cell Biol. (2005)
- Light stimulates MSK1 activation in the suprachiasmatic nucleus via a PACAP-ERK/MAP kinase-dependent mechanism. Butcher, G.Q., Lee, B., Cheng, H.Y., Obrietan, K. J. Neurosci. (2005)
- Tumor necrosis factor activates CRE-binding protein through a p38 MAPK/MSK1 signaling pathway in endothelial cells. Gustin, J.A., Pincheira, R., Mayo, L.D., Ozes, O.N., Kessler, K.M., Baerwald, M.R., Korgaonkar, C.K., Donner, D.B. Am. J. Physiol., Cell Physiol. (2004)
- Phosphorylation of histone H2A inhibits transcription on chromatin templates. Zhang, Y., Griffin, K., Mondal, N., Parvin, J.D. J. Biol. Chem. (2004)
- Regulation of tyrosine hydroxylase by stress-activated protein kinases. Toska, K., Kleppe, R., Armstrong, C.G., Morrice, N.A., Cohen, P., Haavik, J. J. Neurochem. (2002)
- Involvement of JNKs and p38-MAPK/MSK1 pathways in H(2)O(2)-induced upregulation of heme oxygenase-1 mRNA in H9c2 cells. Aggeli, I.K., Gaitanaki, C., Beis, I. Cell. Signal. (2006)
- Low cell cholesterol levels increase NFkappaB activity through a p38 MAPK-dependent mechanism. Calleros, L., Lasa, M., Toro, M.J., Chiloeches, A. Cell. Signal. (2006)
- Rapid access to unexplored chemical space by ligand scanning around a ruthenium center: discovery of potent and selective protein kinase inhibitors. Bregman, H., Carroll, P.J., Meggers, E. J. Am. Chem. Soc. (2006)
- Evidence for a role of MSK1 in transforming growth factor-beta-mediated responses through p38alpha and Smad signaling pathways. Abécassis, L., Rogier, E., Vazquez, A., Atfi, A., Bourgeade, M.F. J. Biol. Chem. (2004)
- Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1). Janknecht, R. Oncogene (2003)
- The Kinases MSK1 and MSK2 Are Required for Epidermal Growth Factor-induced, but Not Tumor Necrosis Factor-induced, Histone H3 Ser10 Phosphorylation. Duncan, E.A., Anest, V., Cogswell, P., Baldwin, A.S. J. Biol. Chem. (2006)
- Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases. Hefner, Y., Borsch-Haubold, A.G., Murakami, M., Wilde, J.I., Pasquet, S., Schieltz, D., Ghomashchi, F., Yates, J.R., Armstrong, C.G., Paterson, A., Cohen, P., Fukunaga, R., Hunter, T., Kudo, I., Watson, S.P., Gelb, M.H. J. Biol. Chem. (2000)
- Marathon running increases ERK1/2 and p38 MAP kinase signalling to downstream targets in human skeletal muscle. Yu, M., Blomstrand, E., Chibalin, A.V., Krook, A., Zierath, J.R. J. Physiol. (Lond.) (2001)
- Involvement of ERKs and mitogen- and stress-activated protein kinase in UVC-induced phosphorylation of ATF2 in JB6 cells. Zhu, F., Zhang, Y., Bode, A.M., Dong, Z. Carcinogenesis (2004)
- Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise. Yu, M., Stepto, N.K., Chibalin, A.V., Fryer, L.G., Carling, D., Krook, A., Hawley, J.A., Zierath, J.R. J. Physiol. (Lond.) (2003)