Gene Review:
MKNK1 - MAP kinase interacting serine/threonine...
Homo sapiens
Synonyms:
MAP kinase signal-integrating kinase 1, MAP kinase-interacting serine/threonine-protein kinase 1, MAPK signal-integrating kinase 1, MNK1, Mnk1
- Phosphorylation of eIF4E by Mnk-1 enhances HSV-1 translation and replication in quiescent cells. Walsh, D., Mohr, I. Genes Dev. (2004)
- Adenovirus-specific translation by displacement of kinase Mnk1 from cap-initiation complex eIF4F. Cuesta, R., Xi, Q., Schneider, R.J. EMBO J. (2000)
- Gene amplification of the Menkes (MNK; ATP7A) P-type ATPase gene of CHO cells is associated with copper resistance and enhanced copper efflux. Camakaris, J., Petris, M.J., Bailey, L., Shen, P., Lockhart, P., Glover, T.W., Barcroft, C., Patton, J., Mercer, J.F. Hum. Mol. Genet. (1995)
- Magnesium may help patients with recessive hereditary inclusion body myopathy, a pathological review. Darvish, D. Med. Hypotheses (2003)
- The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1. Buxadé, M., Parra, J.L., Rousseau, S., Shpiro, N., Marquez, R., Morrice, N., Bain, J., Espel, E., Proud, C.G. Immunity (2005)
- Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment. Jauch, R., Cho, M.K., Jäkel, S., Netter, C., Schreiter, K., Aicher, B., Zweckstetter, M., Jäckle, H., Wahl, M.C. EMBO J. (2006)
- MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates. Fukunaga, R., Hunter, T. EMBO J. (1997)
- Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2. Waskiewicz, A.J., Flynn, A., Proud, C.G., Cooper, J.A. EMBO J. (1997)
- Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2. Knauf, U., Tschopp, C., Gram, H. Mol. Cell. Biol. (2001)
- Identification and molecular characterization of Mnk1b, a splice variant of human MAP kinase-interacting kinase Mnk1. O'Loghlen, A., González, V.M., Piñeiro, D., Pérez-Morgado, M.I., Salinas, M., Martín, M.E. Exp. Cell Res. (2004)
- Features in the N and C termini of the MAPK-interacting kinase Mnk1 mediate its nucleocytoplasmic shuttling. Parra-Palau, J.L., Scheper, G.C., Wilson, M.L., Proud, C.G. J. Biol. Chem. (2003)
- Interleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cells. Grund, E.M., Spyropoulos, D.D., Watson, D.K., Muise-Helmericks, R.C. J. Biol. Chem. (2005)
- The serine-threonine kinase MNK1 is post-translationally stabilized by PML-RARalpha and regulates differentiation of hematopoietic cells. Worch, J., Tickenbrock, L., Schwäble, J., Steffen, B., Cauvet, T., Mlody, B., Buerger, H., Koeffler, H.P., Berdel, W.E., Serve, H., Müller-Tidow, C. Oncogene (2004)
- Elevated Inorganic Phosphate Stimulates Akt-ERK1/2-Mnk1 Signaling in Human Lung Cells. Chang, S.H., Yu, K.N., Lee, Y.S., An, G.H., Beck, G.R., Colburn, N.H., Lee, K.H., Cho, M.H. Am. J. Respir. Cell Mol. Biol. (2006)
- Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases. Hefner, Y., Borsch-Haubold, A.G., Murakami, M., Wilde, J.I., Pasquet, S., Schieltz, D., Ghomashchi, F., Yates, J.R., Armstrong, C.G., Paterson, A., Cohen, P., Fukunaga, R., Hunter, T., Kudo, I., Watson, S.P., Gelb, M.H. J. Biol. Chem. (2000)
- Regulation of sprouty stability by Mnk1-dependent phosphorylation. DaSilva, J., Xu, L., Kim, H.J., Miller, W.T., Bar-Sagi, D. Mol. Cell. Biol. (2006)
- Leucine stimulates procollagen alpha1(I) translation on hepatic stellate cells through ERK and PI3K/Akt/mTOR activation. de Obanos, M.P., Zabalza, M.J., Prieto, J., Herraiz, M.T., Iraburu, M.J. J. Cell. Physiol. (2006)
- Phosphorylation of initiation factor 4E is resistant to SB203580 in cells expressing a drug-resistant mutant of stress-activated protein kinase 2a/p38. Morley, S.J., Naegele, S. Cell. Signal. (2003)
- Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E. Pyronnet, S., Imataka, H., Gingras, A.C., Fukunaga, R., Hunter, T., Sonenberg, N. EMBO J. (1999)
- Regulation of c-jun mRNA expression in adult cardiocytes by MAP kinase interacting kinase-1 (MNK1). Spruill, L.S., McDermott, P.J. FASEB J. (2006)
- Shiga toxin 1-induced cytokine production is mediated by MAP kinase pathways and translation initiation factor eIF4E in the macrophage-like THP-1 cell line. Cherla, R.P., Lee, S.Y., Mees, P.L., Tesh, V.L. J. Leukoc. Biol. (2006)
- Mitogen-activated protein kinase (MAPK) pathway activation: effects of age and acute exercise on human skeletal muscle. Williamson, D., Gallagher, P., Harber, M., Hollon, C., Trappe, S. J. Physiol. (Lond.) (2003)
- Identification of the human Mnk2 gene (MKNK2) through protein interaction with estrogen receptor beta. Slentz-Kesler, K., Moore, J.T., Lombard, M., Zhang, J., Hollingsworth, R., Weiner, M.P. Genomics (2000)
- Molecular mechanisms of copper metabolism and the role of the Menkes disease protein. Harrison, M.D., Dameron, C.T. J. Biochem. Mol. Toxicol. (1999)