Disease relevance of Joint Prosthesis

• Efficacy of sparfloxacin and autoradiographic diffusion pattern of [14C]Sparfloxacin in experimental Staphylococcus aureus joint prosthesis infection [1].
• We reviewed the records of fifty patients who had suspected osteomyelitis or suspected infection about a total joint prosthesis and who underwent scintigraphy with technetium-99m methylene diphosphonate and scintigraphy with indium-111 oxine-labeled white blood cells before an open surgical procedure [2].
• The yearly incidence of bacterial arthritis varies from 2 to 10 per 100,000 in the general population to 30 to 70 per 100,000 in patients with rheumatoid arthritis and in patients with joint prostheses [3].
• Nocardia infection of a joint prosthesis complicating systemic lupus erythematosus [4].
• Finally, unlike IL-2, IL-15 plays a certain role in bone resorption that leads to failed joint prostheses [5].

High impact information on Joint Prosthesis

• Crack growth resistance of alumina, zirconia and zirconia toughened alumina ceramics for joint prostheses [6].
• Image technique optimization in MR imaging of a titanium alloy joint prosthesis [7].
• Moreover, the tibial joint surface which bore against the polyvinyl alcohol hydrogel surface of this implant remained intact, which suggests that this composite is a very promising biomaterial for use in joint prostheses [8].
• Mechanical failure of poly(methyl methacrylate) (PMMA) bone cement is linked to failure of cemented total joint prostheses [9].
• Plasma-sprayed coating of hydroxyapatite are biocompatible and, because of their osteoconductive properties, may contribute to the early fixation of total joint prostheses [10].

Associations of Joint Prosthesis with chemical compounds

• The use of porous metallic coatings for fixation of total joint prostheses by bone ingrowth has become a widespread alternative to fixation with PMMA bone cement [11].
• A thermoplastic polymer, Delrin 150 (polyoxymethylene homopolymer), with creep resistance ten times that of ultrahigh-molecular-weight polyethylene, is used as a material for total joint prostheses [12].
• The radiopharmaceuticals gallium-67 and indium-111 labelled leucocytes have been compared in 15 patients with a painful joint prosthesis in an attempt to identify those patients with periprosthetic infection [13].
• The significance of these findings with regard to the in vivo corrosion of aluminium-containing metal alloy joint prostheses (e.g., TiAlV alloys) is discussed [14].
• Methyl methacrylate monomer can evaporate from bone cement to reach cytotoxic levels of concentrations in the implant bed of total joint prosthesis [15].

Gene context of Joint Prosthesis

• Localization of RANKL in osteolytic tissue around a loosened joint prosthesis [16].
• Postoperative infections in joint prostheses and fracture-fixation devices commonly involve both MRSA and methicillin resistant coagulase-negative staphylococcus [17].
• To investigate if a pro-angiogenic state exists in the bone-implant interface of aseptically loosened joint prosthesis, the expression of vascular endothelial growth factor (VEGF) and its receptor Flk-1/KDR were studied by immunohistochemistry [18].
• 20 patients were operated on consecutively with osseointegrated MCP joint prostheses in 64 joints at our department between September 1993 and February 1995 [19].
• Production of nitric oxide by the inducible NO synthase (iNOS) is known to be enhanced in chronic joint inflammation and osteoarthritis as well as aseptic loosening of joint prostheses [20].

References