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MeSH Review


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Disease relevance of Fetoscopy


Psychiatry related information on Fetoscopy


High impact information on Fetoscopy

  • Fetoscopy is, therefore, an ideal method to study feto-maternal steroid interrelations in human pregnancy [7].
  • Newer, still experimental, techniques (e.g., fatal breathing movements, fetoscopy, and dehydroepiandrosterone plasma clearance) are viewed in light of further possible decreases in maternal and perinatal mortality [8].
  • STUDY DESIGN: Fetoscopy was performed in a total of 100 gestational sacs in 20 does at midgestation (23 days, term = 31 days) [9].
  • Complement factors (C3, C4, C5; Factors B, H and I) were measured in maternal and fetal serum and amniotic fluid obtained from 55 women with singleton pregnancy undergoing diagnostic fetoscopy at 15 to 28 weeks gestation [10].
  • The various clinical pictures which can be associated with vasa previa are presented, along with a discussion of the techniques readily available for making the diagnosis: palpation and visualization, amnioscopy, fetal heart monitoring, and various tests for the presence of fetal hemoglobin [11].

Biological context of Fetoscopy


Anatomical context of Fetoscopy


Associations of Fetoscopy with chemical compounds

  • Reducing the deleterious effects of intrauterine CO2 during fetoscopic surgery [4].
  • Fetal liver biopsy or fetoscopy for purposes other than blood sampling caused a mean delta AFP of 11.4 ng/ml and 34.2 ng/ml, respectively [15].
  • The levels of M-PGF2 alpha and thromboxane B2 rose significantly between 10 and 30 min after amnioscopy but dropped to pre-amnioscopy levels within 60 min, whereas the 6-keto-PGF1 alpha concentration did not change [14].
  • This was particularly common among women who after fetoscopy received routine profylactic terbutalin treatment and had continuous sickleave until the 36th gestational week, 17/29 would consider going through PND in the future [16].
  • Effect of amnioscopy on concentrations of prostaglandin F2 alpha, prostacyclin and thromboxane in maternal plasma [14].

Gene context of Fetoscopy

  • Biochemical examination of fetal skin biopsy specimens obtained by fetoscopy: use of the method for analysis of keratins and filaggrin [17].
  • In one fetus, diastrophic dysplasia was confirmed by fetoscopy and fetal radiograph at 19 weeks of gestation after the parents had decided to terminate the pregnancy [18].
  • CONCLUSION: Using the PSP test in combination with amnioscopy, we have established a method of differentially diagnosing PROM [19].


  1. Prenatal diagnosis of chondroectodermal dysplasia (Ellis-van Creveld syndrome) with fetoscopy and ultrasound. Mahoney, M.J., Hobbins, J.C. N. Engl. J. Med. (1977) [Pubmed]
  2. Ultrasonic assessment of the fetal spine before 20 weeks' gestation. Miskin, M., Baim, R.S., Allen, L.C., Benzie, R.J. Radiology. (1979) [Pubmed]
  3. Nitroglycerin for fetal surgery: fetoscopy and ex utero intrapartum treatment procedure with malignant hyperthermia precautions. Rosen, M.A., Andreae, M.H., Cameron, A.G. Anesth. Analg. (2003) [Pubmed]
  4. Reducing the deleterious effects of intrauterine CO2 during fetoscopic surgery. Saiki, Y., Litwin, D.E., Bigras, J.L., Waddell, J., Konig, A., Baik, S., Navsarikar, A., Rebeyka, I.M. J. Surg. Res. (1997) [Pubmed]
  5. Prenatal diagnosis of cleft lip at 11 menstrual weeks using embryoscopy in the van der Woude syndrome. Dommergues, M., Lemerrer, M., Couly, G., Delezoide, A.L., Dumez, Y. Prenat. Diagn. (1995) [Pubmed]
  6. A new craniosynostosis/mental retardation syndrome diagnosed by fetoscopy. Baraitser, M., Rodeck, C., Garner, A. Clin. Genet. (1982) [Pubmed]
  7. The steroid hormonal milieu of the undisturbed human fetus and mother at 16-20 weeks gestation. Partsch, C.J., Sippell, W.G., MacKenzie, I.Z., Aynsley-Green, A. J. Clin. Endocrinol. Metab. (1991) [Pubmed]
  8. Antepartum evaluation of the high-risk fetus: problems and prospects. Fabro, S. Environ. Health Perspect. (1976) [Pubmed]
  9. Increased polymorphonuclear infiltration and iatrogenic amniotic band after closure of fetoscopic access sites with a bioactive membrane in the rabbit at midgestation. Devlieger, R., Ardon, H., Verbist, L., Gratacós, E., Pijnenborg, R., Deprest, J.A. Am. J. Obstet. Gynecol. (2003) [Pubmed]
  10. Complement factors in fetal and maternal blood and amniotic fluid during the second trimester of normal pregnancy. Stabile, I., Nicolaides, K.H., Bach, A., Teisner, B., Rodeck, C., Westergaard, J.G., Grudzinskas, J.G. British journal of obstetrics and gynaecology. (1988) [Pubmed]
  11. Vasa previa. Pent, D. Am. J. Obstet. Gynecol. (1979) [Pubmed]
  12. Biochemical composition of amniotic fluid in pregnancies complicated with twin-twin transfusion syndrome. Adama van Scheltema, P.N., In't Anker, P.S., Vereecken, A., Vandenbussche, F.P., Kanhai, H.H., Devlieger, R. Fetal. Diagn. Ther. (2005) [Pubmed]
  13. Prenatal diagnosis of mandibulofacial dysostosis. Nicolaides, K.H., Johansson, D., Donnai, D., Rodeck, C.H. Prenat. Diagn. (1984) [Pubmed]
  14. Effect of amnioscopy on concentrations of prostaglandin F2 alpha, prostacyclin and thromboxane in maternal plasma. Ylikorkala, O., Viinikka, L. Gynecol. Obstet. Invest. (1982) [Pubmed]
  15. Changes in maternal serum alpha-fetoprotein levels associated with intrauterine genetic diagnostic procedures. Simpson, G.F., Sun, N.H., Golbus, M.S. Prenat. Diagn. (1984) [Pubmed]
  16. How do carriers of hemophilia experience prenatal diagnosis (PND)? Carriers' Immediate and later reactions to amniocentesis and fetal blood sampling. Tedgård, n.u.l.l., Ljung, R., McNeil, T., Tedgård, E., Schẃartz, M. Acta paediatrica Scandinavica. (1989) [Pubmed]
  17. Biochemical examination of fetal skin biopsy specimens obtained by fetoscopy: use of the method for analysis of keratins and filaggrin. Dale, B.A., Perry, T.B., Holbrook, K.A., Hamilton, E.F., Senikas, V. Prenat. Diagn. (1986) [Pubmed]
  18. Early prenatal detection of diastrophic dysplasia. Kaitila, I., Ammälä, P., Karjalainen, O., Liukkonen, S., Rapola, J. Prenat. Diagn. (1983) [Pubmed]
  19. Clinical usefulness of the dye-injection method for diagnosing premature rupture of the membranes in equivocal cases. Fujimoto, S., Kishida, T., Sagawa, T., Negishi, H., Okuyama, K., Hareyama, H., Makinoda, S. Journal of obstetrics and gynaecology (Tokyo, Japan) (1995) [Pubmed]
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