Disease relevance of Fetoscopy

• Prenatal diagnosis of chondroectodermal dysplasia (Ellis-van Creveld syndrome) with fetoscopy and ultrasound [1].
• The relative roles of ultrasonography, alpha fetoprotein assay, and fetoscopy in the diagnosis of spina bifida are discussed [2].
• Nitroglycerin for fetal surgery: fetoscopy and ex utero intrapartum treatment procedure with malignant hyperthermia precautions [3].
• Fetal hypercarbic acidosis during fetoscopy with CO2 insufflation is reduced by maternal hyperventilation [4].
• Prenatal diagnosis of cleft lip at 11 menstrual weeks using embryoscopy in the van der Woude syndrome [5].

Psychiatry related information on Fetoscopy

• A new craniosynostosis/mental retardation syndrome diagnosed by fetoscopy [6].

High impact information on Fetoscopy

• Fetoscopy is, therefore, an ideal method to study feto-maternal steroid interrelations in human pregnancy [7].
• Newer, still experimental, techniques (e.g., fatal breathing movements, fetoscopy, and dehydroepiandrosterone plasma clearance) are viewed in light of further possible decreases in maternal and perinatal mortality [8].
• STUDY DESIGN: Fetoscopy was performed in a total of 100 gestational sacs in 20 does at midgestation (23 days, term = 31 days) [9].
• Complement factors (C3, C4, C5; Factors B, H and I) were measured in maternal and fetal serum and amniotic fluid obtained from 55 women with singleton pregnancy undergoing diagnostic fetoscopy at 15 to 28 weeks gestation [10].
• The various clinical pictures which can be associated with vasa previa are presented, along with a discussion of the techniques readily available for making the diagnosis: palpation and visualization, amnioscopy, fetal heart monitoring, and various tests for the presence of fetal hemoglobin [11].

Biological context of Fetoscopy

• Specimens were obtained from recipient sacs in 10 pregnancies undergoing fetoscopy for severe midtrimester TTTS [12].

Anatomical context of Fetoscopy

• Four fetuses at risk of the autosomal dominant Treacher-Collins syndrome were examined by fetoscopy in the second trimester of pregnancy [13].
• These findings suggest a local release of PGF2 alpha and Tx-A2 in the myometrium and/or intrauterine tissues as a consequence of amnioscopy [14].

Associations of Fetoscopy with chemical compounds

• Reducing the deleterious effects of intrauterine CO2 during fetoscopic surgery [4].
• Fetal liver biopsy or fetoscopy for purposes other than blood sampling caused a mean delta AFP of 11.4 ng/ml and 34.2 ng/ml, respectively [15].
• The levels of M-PGF2 alpha and thromboxane B2 rose significantly between 10 and 30 min after amnioscopy but dropped to pre-amnioscopy levels within 60 min, whereas the 6-keto-PGF1 alpha concentration did not change [14].
• This was particularly common among women who after fetoscopy received routine profylactic terbutalin treatment and had continuous sickleave until the 36th gestational week, 17/29 would consider going through PND in the future [16].
• Effect of amnioscopy on concentrations of prostaglandin F2 alpha, prostacyclin and thromboxane in maternal plasma [14].

Gene context of Fetoscopy

• Biochemical examination of fetal skin biopsy specimens obtained by fetoscopy: use of the method for analysis of keratins and filaggrin [17].
• In one fetus, diastrophic dysplasia was confirmed by fetoscopy and fetal radiograph at 19 weeks of gestation after the parents had decided to terminate the pregnancy [18].
• CONCLUSION: Using the PSP test in combination with amnioscopy, we have established a method of differentially diagnosing PROM [19].

References