Disease relevance of Hemothorax

• Hepatocellular carcinoma with pleural metastasis complicated by hemothorax [1].
• These included recurrent PE (four), subdural hematomas (three), hemothorax (two), heparin-induced thrombocytopenia (one), hemorrhagic pericardial effusion (one), retroperitoneal hematoma (one), and sudden unexplained drop in hemoglobin and shock (one) [2].
• Neither hemothorax nor pneumothorax are well recognized manifestations of systemic lupus erythematosus (SLE) [3].
• Tranexamic acid treatment of hemothorax in two patients with malignant mesothelioma [4].
• Ectopic pregnancy causing hemothorax managed by thoracoscopy and actinomycin D [5].

High impact information on Hemothorax

• A case of a ruptured thymoma causing mediastinal hemorrhage and hemothorax that was electively resected by a partial sternotomy approach is presented [6].
• Delayed traumatic hemothorax on ticlopidine and aspirin for coronary stent [7].
• We have reported previously that there is a high incidence of hemothorax and substantial mortality in rabbits that are given tetracycline derivatives intrapleurally [8].
• Higher doses of minocycline (> or = 20 mg/kg) produce a high mortality that seems to be related to hemothorax [9].
• Other procedures successfully performed were lung biopsy/wedge resection (6), lung cancer staging procedures (3), lobectomy (1), hemothorax (3), chest wall neurinoma (2), sympathectomy (5), dorsal mediastinal neurinoma (1), thymectomy (1), esophagectomy (3), benign esophageal tumor enucleation (2), and Belsey Mark IV antireflux procedure (1) [10].

Chemical compound and disease context of Hemothorax

• The delayed traumatic hemothorax in this case occurred on treatment with ticlopidine and did not recur with continuation of aspirin alone [7].

Anatomical context of Hemothorax

• All cases with FR had the mediastinal abnormalities of "grossly widened mediastinum" + hemothorax; 10/11 had an episode of transient hypotension that initially responded to fluid resuscitation before their terminal event [11].
• 2 days later--after diagnosis of an extended hemothorax: 1500 ml blood were obtained after thoracocentesis, transfusion of packed red blood cells was necessary--rt-PA was stopped, with only heparin (400 U/kg/d) being administered [12].
• During placement, the superior vena cava, pleura, and pulmonary tissue were punctured, resulting in a tension pneumo/hemothorax, the detection of which was complicated by its slow onset and unusual location [13].

Gene context of Hemothorax

• BACKGROUND:: This study is aimed at evaluating the safety and efficacy of intrapleural tissue plasminogen activator (TPA) for complicated pleural effusions, including posttraumatic hemothorax [14].
• Hemothorax can be caused by rupture of hepatocellular carcinoma (HCC) [1].
• This rare case of hemothorax with hereditary multiple exostoses is made even rarer by the concomitant perforation of the diaphragm [15].
• Complications such as hemothorax, filter misplacement, and vena cava perforation were identified [16].
• Delayed ICD patch migration after thoracoscopic placement with resultant hemothorax [17].

References