Gene Review:
CSF2 - colony stimulating factor 2 (granulocyte...
Homo sapiens
Synonyms:
CSF, Colony-stimulating factor, GM-CSF, GMCSF, Granulocyte-macrophage colony-stimulating factor, ...
- A comparison of treatment of canine cyclic hematopoiesis with recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF), G-CSF interleukin-3, and canine G-CSF. Hammond, W.P., Boone, T.C., Donahue, R.E., Souza, L.M., Dale, D.C. Blood (1990)
- Effect of human immunodeficiency virus type-1 envelope glycoprotein gp160 on cytokine production from cord-blood T cells. Than, S., Oyaizu, N., Pahwa, R.N., Kalyanaraman, V.S., Pahwa, S. Blood (1994)
- Interleukin-3 and granulocyte-monocyte colony-stimulating factor receptors on human acute myelocytic leukemia cells and relationship to the proliferative response. Budel, L.M., Touw, I.P., Delwel, R., Clark, S.C., Löwenberg, B. Blood (1989)
- Effects of recombinant human granulocyte colony-stimulating factor (CSF), human granulocyte macrophage-CSF, and gibbon interleukin-3 on hematopoiesis in human long-term bone marrow culture. Coutinho, L.H., Will, A., Radford, J., Schiró, R., Testa, N.G., Dexter, T.M. Blood (1990)
- Suppression of interleukin-12 production by human monocytes after preincubation with lipopolysaccharide. Wittmann, M., Larsson, V.A., Schmidt, P., Begemann, G., Kapp, A., Werfel, T. Blood (1999)
- Biologic Activity of Autologous, Granulocyte-Macrophage Colony-Stimulating Factor Secreting Alveolar Soft-Part Sarcoma and Clear Cell Sarcoma Vaccines. Goldberg, J.M., Fisher, D.E., Demetri, G.D., Neuberg, D., Allsop, S.A., Fonseca, C., Nakazaki, Y., Nemer, D., Raut, C.P., George, S., Morgan, J.A., Wagner, A.J., Freeman, G.J., Ritz, J., Lezcano, C., Mihm, M., Canning, C., Hodi, F.S., Dranoff, G. Clin. Cancer Res. (2015)
- GM-CSF promotes proliferation of human fetal and adult microglia in primary cultures. Lee, S.C., Liu, W., Brosnan, C.F., Dickson, D.W. Glia (1994)
- Autografting with peripheral blood stem cells mobilized by sequential interleukin-3/granulocyte-macrophage colony-stimulating factor following high-dose chemotherapy in non-Hodgkin's lymphoma. Haas, R., Ehrhardt, R., Witt, B., Goldschmidt, H., Hohaus, S., Pförsich, M., Ehrlich, H., Färber, L., Hunstein, W. Bone Marrow Transplant. (1993)
- A cross-reactive anti-myelin basic protein idiotope in cerebrospinal fluid cells in multiple sclerosis. Zhou, S.R., Maier, C.C., Mitchell, G.W., LaGanke, C.C., Blalock, J.E., Whitaker, J.N. Neurology (1998)
- Tumour necrosis factor (TNF-alpha) and neurological disorders in HIV infection. Mastroianni, C.M., Paoletti, F., Valenti, C., Vullo, V., Jirillo, E., Delia, S. J. Neurol. Neurosurg. Psychiatr. (1992)
- Epstein-Barr virus induces GM-CSF synthesis by monocytes: effect on EBV-induced IL-1 and IL-1 receptor antagonist production in neutrophils. Roberge, C.J., Larochelle, B., Rola-Pleszczynski, M., Gosselin, J. Virology (1997)
- Cytokine receptors and signal transduction. Miyajima, A., Kitamura, T., Harada, N., Yokota, T., Arai, K. Annu. Rev. Immunol. (1992)
- The clinical use of colony stimulating factors. Moore, M.A. Annu. Rev. Immunol. (1991)
- The dendritic cell system and its role in immunogenicity. Steinman, R.M. Annu. Rev. Immunol. (1991)
- Granulocyte-macrophage colony-stimulating factor after initial chemotherapy for elderly patients with primary acute myelogenous leukemia. Cancer and Leukemia Group B. Stone, R.M., Berg, D.T., George, S.L., Dodge, R.K., Paciucci, P.A., Schulman, P., Lee, E.J., Moore, J.O., Powell, B.L., Schiffer, C.A. N. Engl. J. Med. (1995)
- Interleukin 1 and tumor necrosis factor-alpha additively increase the levels of granulocyte-macrophage and granulocyte colony-stimulating factor (CSF) mRNA in human fibroblasts. Seelentag, W., Mermod, J.J., Vassalli, P. Eur. J. Immunol. (1989)
- Effects of ONO-1078 (pranlukast) on cytokine production in peripheral blood mononuclear cells of patients with bronchial asthma. Tohda, Y., Nakahara, H., Kubo, H., Haraguchi, R., Fukuoka, M., Nakajima, S. Clin. Exp. Allergy (1999)
- Inducing and enhancing effects of IL-3, -5, and -6 and GM-CSF on histamine release from human basophils. Miadonna, A., Roncarolo, M.G., Lorini, M., Tedeschi, A. Clin. Immunol. Immunopathol. (1993)
- Bioassay of human granulocyte colony-stimulating factor using human promyelocytic HL-60 cells. Yamaguchi, T., Yamaguchi, T., Kogi, M., Yamamoto, Y., Hayakawa, T. Biol. Pharm. Bull. (1997)
- Interleukin 3 and granulocyte/macrophage-colony-stimulating factor render human basophils responsive to low concentrations of complement component C3a. Bischoff, S.C., de Weck, A.L., Dahinden, C.A. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Linkage mapping of the human CSF2 and IL3 genes. Frolova, E.I., Dolganov, G.M., Mazo, I.A., Smirnov, D.V., Copeland, P., Stewart, C., O'Brien, S.J., Dean, M. Proc. Natl. Acad. Sci. U.S.A. (1991)
- KRAS2 oncogene overexpression in myelodysplastic syndrome with translocation 5;12. Srivastava, A., Boswell, H.S., Heerema, N.A., Nahreini, P., Lauer, R.C., Antony, A.C., Hoffman, R., Tricot, G.J. Cancer Genet. Cytogenet. (1988)
- Novel single nucleotide polymorphisms of the human colony-stimulating factor 2 (CSF2) gene identified by sequencing the entire gene. Kajita, M., Iwasaki, H., Ota, N., Shinohara, Y., Kodaira, M., Nakajima, T., Emi, M. J. Hum. Genet. (2001)
- Gene for the alpha-subunit of the human interleukin-3 receptor (IL3RA) localized to the X-Y pseudoautosomal region. Milatovich, A., Kitamura, T., Miyajima, A., Francke, U. Am. J. Hum. Genet. (1993)
- IL-6 switches the differentiation of monocytes from dendritic cells to macrophages. Chomarat, P., Banchereau, J., Davoust, J., Palucka, A.K. Nat. Immunol. (2000)
- Production of hematopoietic colony-stimulating factors by human natural killer cells. Cuturi, M.C., Anegón, I., Sherman, F., Loudon, R., Clark, S.C., Perussia, B., Trinchieri, G. J. Exp. Med. (1989)
- Functional NF-IL6/CCAAT enhancer-binding protein is required for tumor necrosis factor alpha-inducible expression of the granulocyte colony-stimulating factor (CSF), but not the granulocyte/macrophage CSF or interleukin 6 gene in human fibroblasts. Kiehntopf, M., Herrmann, F., Brach, M.A. J. Exp. Med. (1995)
- Human recombinant granulocyte-macrophage colony-stimulating factor and interleukin 3 cause basophil histamine release. Haak-Frendscho, M., Arai, N., Arai, K., Baeza, M.L., Finn, A., Kaplan, A.P. J. Clin. Invest. (1988)
- Signal transduction of the human granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors involves tyrosine phosphorylation of a common set of cytoplasmic proteins. Kanakura, Y., Druker, B., Cannistra, S.A., Furukawa, Y., Torimoto, Y., Griffin, J.D. Blood (1990)
- Expression of colony-stimulating factor genes by normal human mesothelial cells and human malignant mesothelioma cells lines in vitro. Demetri, G.D., Zenzie, B.W., Rheinwald, J.G., Griffin, J.D. Blood (1989)
- Human interleukin-6 supports granulocytic differentiation of hematopoietic progenitor cells and acts synergistically with GM-CSF. Caracciolo, D., Clark, S.C., Rovera, G. Blood (1989)
- Common binding structure for granulocyte macrophage colony-stimulating factor and interleukin-3 on human acute myeloid leukemia cells and monocytes. Budel, L.M., Elbaz, O., Hoogerbrugge, H., Delwel, R., Mahmoud, L.A., Löwenberg, B., Touw, I.P. Blood (1990)
- Interleukin-5, interleukin-3, and granulocyte-macrophage colony-stimulating factor cross-compete for binding to cell surface receptors on human eosinophils. Lopez, A.F., Vadas, M.A., Woodcock, J.M., Milton, S.E., Lewis, A., Elliott, M.J., Gillis, D., Ireland, R., Olwell, E., Park, L.S. J. Biol. Chem. (1991)
- Recruitment of dendritic cells and enhanced antigen-specific immune reactivity in cancer patients treated with hr-GM-CSF (Molgramostim) and hr-IL-2. results from a phase Ib clinical trial. Correale, P., Campoccia, G., Tsang, K.Y., Micheli, L., Cusi, M.G., Sabatino, M., Bruni, G., Sestini, S., Petrioli, R., Pozzessere, D., Marsili, S., Fanetti, G., Giorgi, G., Francini, G. Eur. J. Cancer (2001)
- Cytokine regulation of granulocyte-macrophage colony-stimulating factor (GM-CSF) production by human retinal pigment epithelial cells. Crane, I.J., Kuppner, M.C., McKillop-Smith, S., Wallace, C.A., Forrester, J.V. Clin. Exp. Immunol. (1999)
- Roles of JAK kinase in human GM-CSF receptor signals. Watanabe, S., Itoh, T., Arai, K. Leukemia (1997)
- A truncated isoform of the human beta chain common to the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3), and IL-5 with increased mRNA expression in some patients with acute leukemia. Gale, R.E., Freeburn, R.W., Khwaja, A., Chopra, R., Linch, D.C. Blood (1998)
- The role of STAT3 in granulocyte colony-stimulating factor-induced enhancement of neutrophilic differentiation of Me2SO-treated HL-60 cells. GM-CSF inhibits the nuclear translocation of tyrosine-phosphorylated STAT3. Yamaguchi, T., Mukasa, T., Uchida, E., Kanayasu-Toyoda, T., Hayakawa, T. J. Biol. Chem. (1999)
- Role of defective ERK phosphorylation in the impaired GM-CSF-induced oxidative response of neutrophils in elderly humans. Tortorella, C., Stella, I., Piazzolla, G., Simone, O., Cappiello, V., Antonaci, S. Mech. Ageing Dev. (2004)
- Phorbol ester inhibits granulocyte-macrophage colony-stimulating factor binding and tyrosine phosphorylation. Gomez-Cambronero, J., Huang, C.K., Yamazaki, M., Wang, E., Molski, T.F., Becker, E.L., Sha'afi, R.I. Am. J. Physiol. (1992)
- CD1b is expressed in multiple sclerosis lesions. Battistini, L., Fischer, F.R., Raine, C.S., Brosnan, C.F. J. Neuroimmunol. (1996)
- Interleukin 6 is a permissive factor for monocytic colony formation by human hematopoietic progenitor cells. Jansen, J.H., Kluin-Nelemans, J.C., Van Damme, J., Wientjens, G.J., Willemze, R., Fibbe, W.E. J. Exp. Med. (1992)
- Interleukin 10 inhibits growth and granulocyte/macrophage colony-stimulating factor production in chronic myelomonocytic leukemia cells. Geissler, K., Ohler, L., Födinger, M., Virgolini, I., Leimer, M., Kabrna, E., Kollars, M., Skoupy, S., Bohle, B., Rogy, M., Lechner, K. J. Exp. Med. (1996)
- Expression and factor-dependent modulation of the interleukin-3 receptor subunits on human hematopoietic cells. Sato, N., Caux, C., Kitamura, T., Watanabe, Y., Arai, K., Banchereau, J., Miyajima, A. Blood (1993)
- Effect of granulocyte-macrophage colony-stimulating factor and interleukin-3 on interleukin-8 production by human neutrophils and monocytes. Takahashi, G.W., Andrews, D.F., Lilly, M.B., Singer, J.W., Alderson, M.R. Blood (1993)
- Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. Kitamura, T., Sato, N., Arai, K., Miyajima, A. Cell (1991)
- Tyrosine phosphorylation of DNA binding proteins by multiple cytokines. Larner, A.C., David, M., Feldman, G.M., Igarashi, K., Hackett, R.H., Webb, D.S., Sweitzer, S.M., Petricoin, E.F., Finbloom, D.S. Science (1993)
- Cytokines in chronic inflammatory arthritis. IV. Granulocyte/macrophage colony-stimulating factor-mediated induction of class II MHC antigen on human monocytes: a possible role in rheumatoid arthritis. Alvaro-Gracia, J.M., Zvaifler, N.J., Firestein, G.S. J. Exp. Med. (1989)
- Cytokine regulation of colony-stimulating factor (CSF) production in cultured human synovial fibroblasts. II. Similarities and differences in the control of interleukin-1 induction of granulocyte-macrophage CSF and granulocyte-CSF production. Hamilton, J.A., Piccoli, D.S., Cebon, J., Layton, J.E., Rathanaswani, P., McColl, S.R., Leizer, T. Blood (1992)
- Decreased macrophage colony-stimulating factor mRNA expression from activated cord versus adult mononuclear cells: altered posttranscriptional stability. Suen, Y., Lee, S.M., Schreurs, J., Knoppel, E., Cairo, M.S. Blood (1994)