Disease relevance of Carcinoma, Verrucous

• A peroxidase-antiperoxidase method for the detection of filaggrin was applied to specimens from 9 cases of leukoplakia, 5 cases of verrucous carcinomas, 2 cases of carcinoma in situ, and 5 cases of invasive carcinoma [1].
• The presence of human papilloma virus (HPV) DNA in verrucous carcinomas and some squamous-cell carcinomas (SCC) of the oropharynx suggests a role for the virus in their pathogenesis [2].
• RESULTS: Five of 86 white and uncircumcised men with genital LS (mean age at diagnosis, 53 years; range, 22-83 years) showed malignant or premalignant histopathologic features: 3 had SCC, one had erythroplasia of Queyrat (unifocal SCC in situ), and one verrucous carcinoma [3].
• Verrucous hyperplasia and verrucous carcinoma of the rat oral mucosa. Experimental oral carcinogenesis using 4-nitroquinoline 1-oxide [4].
• The immunoperoxidase method for involucrin detection was applied to the study of the maturation of epithelial lesions of the oral mucosa that included specimens of leukoplakia, lichen planus, verrucous carcinoma, carcinoma in situ and invasive carcinoma [5].

High impact information on Carcinoma, Verrucous

• Capecitabine induces rapid, sustained response in two patients with extensive oral verrucous carcinoma [6].
• Northern blot analysis revealed that cornifin-alpha mRNA was present in all the squamous epithelial tissues studied, whereas cornifin-beta mRNA was expressed in oral mucosal epithelia and verrucous carcinoma of the skin but neither in normal nor in psoriatic skin [7].
• Archival tissue biopsies of 17 cases of oral verrucous carcinoma were tested for human papillomaviruses by polymerase chain reaction followed by DNA slot-blot hybridization [8].
• CONCLUSION: This seems to be the first case of vulvar verrucous carcinoma in a patient with Turner syndrome [9].
• Treatment of verrucous carcinoma of vulva with acitretin [10].

Chemical compound and disease context of Carcinoma, Verrucous

• Bleomycin iontophoretic therapy for verrucous carcinoma [11].
• Radiochemotherapy with Vinblastine, Methotrexate, and Bleomycin in the treatment of verrucous carcinoma of the head and neck [12].
• The CO2 laser has been found to be an indispensable tool in the transoral management of T1 carcinomas, multiple superficial carcinoma, extensive leukoplakia and verrucous carcinoma [13].
• The initial exophytic neoplasm excised from the coronal sulcus and prepuce on the abdominal side of the penis was diagnosed histologically as verrucous carcinoma [14].
• Successful treatment of an extensive verrucous carcinoma with topical 5-aminolevulinic acid-mediated photodynamic therapy [15].

Anatomical context of Carcinoma, Verrucous

• Shifts in cellular localization of moesin in normal oral epithelium, oral epithelial dysplasia, verrucous carcinoma and oral squamous cell carcinoma [16].
• All other squamous cell carcinomas, the case of verrucous carcinoma and that of adenoid cystic carcinoma were successfully amplified only with internal control human beta-globin primers [17].
• Verrucous carcinoma of the oral cavity treated with bleomycin [18].

Gene context of Carcinoma, Verrucous

• One of these was a verrucous carcinoma in which the p53 gene products might be inactivated by the oncoprotein E6 of human papilloma virus [19].
• Immunohistochemical expression of Mdm2 and p53 in penile verrucous carcinoma [20].
• The cytoplasmic expression of both ERK-1 and ERK-2 was predominantly negative in the most basal layers of the epithelium in the verrucous carcinomas, but was positive in the suprabasalar region of the epithelium [21].
• p53, Rb, and cyclin D1 expression in human oral verrucous carcinomas [22].
• DESIGN: Seventeen verrucous carcinomas and 10 squamous cell carcinomas of the upper aerodigestive tract were examined for the immunohistochemical expression of ERK-1, ERK-2, and Raf-1 product [21].

Analytical, diagnostic and therapeutic context of Carcinoma, Verrucous

• Subungual verrucous carcinoma of the thumb treated by intra-arterial infusion with methotrexate [23].
• HPV DNA in situ hybridization for HPV Types 6/11, 16/18, and 31/33/35 was performed on formalin-fixed, paraffin-embedded tissue from six cases of verrucous carcinoma and four cases of condyloma acuminatum in perianal specimens from HIV-seropositive patients [24].
• Twenty-seven oral squamous cell carcinomas and eight verrucous carcinomas were analyzed for the presence of HPV DNA using the polymerase chain reaction, followed by Southern blot and probe hybridization [25].

References