Disease relevance of Strongyloidiasis

• Sputum Gram stain may be a useful procedure to screen for pulmonary strongyloidiasis in steroid-treated patients with chronic lung disease who come from an endemic area [1].
• Thiabendazole for the treatment of strongyloidiasis in patients with hematologic malignancies [2].
• Thiabendazole for the prophylaxis of strongyloidiasis in immunosuppressed patients with hematological diseases: a randomized double-blind placebo-controlled study [3].
• Cambendazole was used for the treatment of strongyloidiasis in 40 hospitalized patients, given in a single dose of 5 mg/kg body weight [4].
• Successful use of parenteral ivermectin in an immunosuppressed patient with disseminated strongyloidiasis and septic shock [5].

High impact information on Strongyloidiasis

• Thiabendazole treatment of severe strongyloidiasis in a hemodialyzed patient [6].
• Our case illustrates the difficulty of eliminating S stercoralis from a blind loop of the bowel and indicates that mebendazole therapy used in adequate doses is effective treatment for strongyloidiasis [7].
• Serum IgG reactivity with 41-, 31-, and 28-kDa larval proteins of Strongyloides stercoralis in individuals with strongyloidiasis [8].
• Concentrations of thiabendazole and parasite-specific IgG antibodies in the cerebrospinal fluid of a patient with disseminated strongyloidiasis [9].
• Cyclosporine may eliminate the threat of overwhelming strongyloidiasis in immunosuppressed patients [10].

Chemical compound and disease context of Strongyloidiasis

• It is concluded that albendazole may be effective treatment for strongyloidiasis if it is given in sufficiently large doses [11].
• Comparison of the quantitative formalin ethyl acetate concentration technique and agar plate culture for diagnosis of human strongyloidiasis [12].
• Cambendazole in the treatment of human strongyloidiasis [4].
• Parenteral administration of ivermectin in a patient with disseminated strongyloidiasis [13].
• Effects of prednisolone on murine strongyloidiasis [14].

Biological context of Strongyloidiasis

• The patient died suddenly from severe cardiorespiratory failure while he was under mebendazole treatment (100 mg b.i.d.). Strongyloidiasis occurs mostly in immunocompromised hosts, as in patients with chronic pulmonary diseases on long-term treatment with corticosteroids, oncology patients under treatment and patients with AIDS [15].
• Cross reactions were observed with sera from patients with paragonimiasis and strongyloidiasis [16].

Anatomical context of Strongyloidiasis

• This study compared the expression of CD23, CD32, Mac-1 and other adhesion molecules in eosinophils of patients with strongyloidiasis positive for anti-(HTLV-I) antibodies and in those negative for the antibodies [17].

Gene context of Strongyloidiasis

• The expression of CD23, Mac-1 and intercellular adhesion molecule-1 (ICAM-1) on eosinophils of patients with strongyloidiasis was augmented in comparison with normal subjects and HTLV-I carriers [17].
• Sera from two groups of patients with strongyloidiasis proven by parasitologic methods, including one group of 29 coded positive sera, and from presumed normal subjects as controls were tested [18].
• L3 antigen-specific antibody isotype responses in human strongyloidiasis: correlations with larval output [19].
• Disseminated strongyloidiasis is reported in a patients with systemic lupus erythematosus treated with corticosteroids in whom a reactive hemophagocytic syndrome developed and who finally died [20].
• A non insulin-dependent Zairian patient developed ketoacidosis and then overwhelming strongyloidiasis following ACTH treatment [21].

Analytical, diagnostic and therapeutic context of Strongyloidiasis

• Disseminated strongyloidiasis complicating acute renal allograft rejection. Prolonged thiabendazole administration and successful retransplantation [22].
• Treatment failures following mebendazole therapy for chronic strongyloidiasis [23].
• Sera from 68 patients with parasitologically proven strongyloidiasis were tested by the ELISA and IHA tests using larval antigens prepared from Strongyloides stercoralis and Strongyloides ratti [24].
• Both the ELISA following incubation of sera with O. gutturosa extract and serum IgG reactivity to a 41-kD larval component using immunoblotting are sensitive and specific techniques for diagnosing endemic strongyloidiasis [25].
• Treatment of human strongyloidiasis with cambendazole, a new anthelminthic. Double-blind study [26].

References