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Disease relevance of Strongyloides


High impact information on Strongyloides


Chemical compound and disease context of Strongyloides


Biological context of Strongyloides


Anatomical context of Strongyloides

  • The patient's condition failed to improve with high-dose steroid therapy, but he recovered rapidly after Strongyloides larvae were found in stool and sputum and treatment with thiabendazole was begun [20].
  • Cortisone (5 mg daily subcutaneously) suppressed both primary and secondary immune explusion of Strongyloides ratti, and reduced the intestinal mast cell response, but did not induce hyperinfection in rats [21].
  • Thiabendazole 50 mg/kg daily produced a 91% reduction in the numbers of Strongyloides ratti larvae in the feces [22].
  • Mast-cell growth factor (MCGF) activity in the media conditioned by mesenteric lymph node or spleen cells from Strongyloides ratti-infected C57BL/6 mice was examined by using factor-dependent cell line FDC-P2 or bone marrow-derived, cultured mast cells (BMMC) as indicators [23].
  • When compared with uninfected control dogs, no significant differences were seen in PHA stimulation of peripheral blood lymphocytes, nor did significant lymphocyte proliferation occur in the presence of Strongyloides antigen [24].

Associations of Strongyloides with chemical compounds

  • This study examines the role of complement components C3 and C5 in innate and adaptive protective immunity to larval Strongyloides stercoralis in mice [9].
  • Three courses of thiabendazole therapy, including one course given directly into a blind loop of the bowel, failed to eradicate Strongyloides stercoralis from a 55-year-old man who had undergone a Roux-en-Y operation [1].
  • Persistent Strongyloides stercoralis in a blind loop of the bowel. Successful treatment with mebendazole [1].
  • Another example of Strongyloides stercoralis infection associated with cimetidine in an immunosuppressed patient [25].
  • The quantitative formalin ethyl acetate concentration technique (QFEC) was compared to agar plate culture (APC) for the detection of Strongyloides stercoralis larvae [26].

Gene context of Strongyloides


Analytical, diagnostic and therapeutic context of Strongyloides


  1. Persistent Strongyloides stercoralis in a blind loop of the bowel. Successful treatment with mebendazole. Wilson, K.H., Kauffman, C.A. Arch. Intern. Med. (1983) [Pubmed]
  2. Detection of Strongyloides stercoralis in the cerebrospinal fluid of a patient with acquired immunodeficiency syndrome. Takayanagui, O.M., Lofrano, M.M., Araúgo, M.B., Chimelli, L. Neurology (1995) [Pubmed]
  3. Vancomycin-resistant Enterococcus faecium meningitis successfully managed with linezolid: case report and review of the literature. Zeana, C., Kubin, C.J., Della-Latta, P., Hammer, S.M. Clin. Infect. Dis. (2001) [Pubmed]
  4. Severe strongyloidiasis associated with hypogammaglobulinaemia. Brandt de Oliveira, R., Voltarelli, J.C., Meneghelli, U.G. Parasite Immunol. (1981) [Pubmed]
  5. Respiratory failure due to Strongyloides stercoralis in a patient with a renal transplant. Venizelos, P.C., Lopata, M., Bardawil, W.A., Sharp, J.T. Chest (1980) [Pubmed]
  6. IL-18 with IL-2 protects against Strongyloides venezuelensis infection by activating mucosal mast cell-dependent type 2 innate immunity. Sasaki, Y., Yoshimoto, T., Maruyama, H., Tegoshi, T., Ohta, N., Arizono, N., Nakanishi, K. J. Exp. Med. (2005) [Pubmed]
  7. Image of the month. Strongyloides stercoralis hyperinfection and syndrome of inappropriate secretion of antidiuretic hormone. Seet, R.C., Gong, L.L., Tambyath, P.A. Gastroenterology (2005) [Pubmed]
  8. Parenteral ivermectin in Strongyloides hyperinfection. Chiodini, P.L., Reid, A.J., Wiselka, M.J., Firmin, R., Foweraker, J. Lancet (2000) [Pubmed]
  9. Complement component C3 is required for protective innate and adaptive immunity to larval strongyloides stercoralis in mice. Kerepesi, L.A., Hess, J.A., Nolan, T.J., Schad, G.A., Abraham, D. J. Immunol. (2006) [Pubmed]
  10. Appendiceal infection by Entamoeba histolytica and Strongyloides stercoralis presenting like acute appendicitis. Nadler, S., Cappell, M.S., Bhatt, B., Matano, S., Kure, K. Dig. Dis. Sci. (1990) [Pubmed]
  11. Syndrome of inappropriate secretion of antidiuretic hormone and nonpalpable purpura in a woman with Strongyloides stercoralis hyperinfection. Reddy, T.S., Myers, J.W. Am. J. Med. Sci. (2003) [Pubmed]
  12. Assay of nematocidal activity of isoquinoline alkaloids using third-stage larvae of Strongyloides ratti and S. venezuelensis. Satou, T., Koga, M., Matsuhashi, R., Koike, K., Tada, I., Nikaido, T. Vet. Parasitol. (2002) [Pubmed]
  13. L-dopa malabsorption in a parkinsonian patient with Strongyloides stercoralis duodenitis. Gatto, M., Fernandez Pardal, M., Melero, M., Zurru, C., Scorticati, C., Micheli, F. Clinical neuropharmacology. (1994) [Pubmed]
  14. Comparison of albendazole regimen for prophylaxis of strongyloides hyperinfection in nephrotic syndrome patients on long-term steroids in Cambodia. Leang, B., Lynen, L., Schrooten, W., Hines, J. Tropical doctor. (2005) [Pubmed]
  15. Platelet-activating factor receptor deficiency delays elimination of adult worms but reduces fecundity in Strongyloides venezuelensis-infected mice. Negrão-Corrêa, D., Souza, D.G., Pinho, V., Barsante, M.M., Souza, A.L., Teixeira, M.M. Infect. Immun. (2004) [Pubmed]
  16. The response of intact Strongyloides ratti infective (L3) larvae to substrates and inhibitors of respiratory electron transport. Mendis, A.H., Armson, A., Thompson, R.C., Grubb, W.B. Int. J. Parasitol. (1991) [Pubmed]
  17. Ss40: the zinc endopeptidase secreted by infective larvae of Strongyloides stercoralis. Brindley, P.J., Gam, A.A., McKerrow, J.H., Neva, F.A. Exp. Parasitol. (1995) [Pubmed]
  18. Effect of androgen on the expression of the sex difference in susceptibility to infection with Strongyloides ratti in C57BL/6 mice. Kiyota, M., Korenaga, M., Nawa, Y., Kotani, M. The Australian journal of experimental biology and medical science. (1984) [Pubmed]
  19. Intestinal absorption of palmitate and 2-aminoisobutyric acid in piglets infected with Strongyloides ransomi. Dey-Hazra, A., Enigk, K., Kolm, H.P. Res. Vet. Sci. (1977) [Pubmed]
  20. Strongyloides stercoralis hyperinfection masquerading as cerebral vasculitis. Wachter, R.M., Burke, A.M., MacGregor, R.R. Arch. Neurol. (1984) [Pubmed]
  21. Strongyloides ratti infections in rats. II. Effects of cortisone treatment. Olson, C.E., Schiller, E.L. Am. J. Trop. Med. Hyg. (1978) [Pubmed]
  22. Strongyloides ratti and S. stercoralis: the effects of thiabendazole, mebendazole, and cambendazole in infected mice. Grove, D.I. Am. J. Trop. Med. Hyg. (1982) [Pubmed]
  23. Kinetic study of mast-cell growth factor production by lymphocytes during the course of Strongyloides ratti infection in mice. Abe, T., Nawa, Y. Parasitol. Res. (1988) [Pubmed]
  24. Infection and immunity in dogs infected with a human strain of Strongyloides stercoralis. Grove, D.I., Northern, C. Trans. R. Soc. Trop. Med. Hyg. (1982) [Pubmed]
  25. Another example of Strongyloides stercoralis infection associated with cimetidine in an immunosuppressed patient. Cadranel, J.F., Eugene, C. Gut (1986) [Pubmed]
  26. Comparison of the quantitative formalin ethyl acetate concentration technique and agar plate culture for diagnosis of human strongyloidiasis. Intapan, P.M., Maleewong, W., Wongsaroj, T., Singthong, S., Morakote, N. J. Clin. Microbiol. (2005) [Pubmed]
  27. Interferon-gamma and interleukin-4 responses in relation to serum IgE levels in persons infected with human T lymphotropic virus type I and Strongyloides stercoralis. Neva, F.A., Filho, J.O., Gam, A.A., Thompson, R., Freitas, V., Melo, A., Carvalho, E.M. J. Infect. Dis. (1998) [Pubmed]
  28. The effect of interleukin-4 on the induction of intestinal mast cells and chronological cytokine profiles during intestinal nematode Strongyloides ratti infection. Watanabe, K., Hamano, S., Yada, S., Noda, K., Kishihara, K., Nomoto, K., Tada, I. Parasitol. Res. (2001) [Pubmed]
  29. Analysis of T cell populations and IL-3 mRNA expression in mesenteric lymph node cells and intestinal intraepithelial lymphocytes in Strongyloides ratti-infected mice. Abe, T., Sugaya, H., Yoshimura, K. J. Helminthol. (1998) [Pubmed]
  30. Clinical infection with Strongyloides sterocoralis following etanercept use for rheumatoid arthritis. Boatright, M.D., Wang, B.W. Arthritis Rheum. (2005) [Pubmed]
  31. Regulation of primary Strongyloides ratti infections in mice: a role for interleukin-5. Ovington, K.S., McKie, K., Matthaei, K.I., Young, I.G., Behm, C.A. Immunology (1998) [Pubmed]
  32. Strongyloides hyperinfection in a renal transplant recipient receiving cyclosporine: possible Strongyloides stercoralis transmission by kidney transplant. Palau, L.A., Pankey, G.A. Am. J. Trop. Med. Hyg. (1997) [Pubmed]
  33. An intervention study using thiabendazole suspension against Strongyloides fuelleborni-like infections in Papua New Guinea. Barnish, G., Barker, J. Trans. R. Soc. Trop. Med. Hyg. (1987) [Pubmed]
  34. Clinical trials with fenbendazole and oxibendazole for Strongyloides westeri infection in foals. Drudge, J.H., Lyons, E.T., Tolliver, S.C., Kubis, J.E. Am. J. Vet. Res. (1981) [Pubmed]
  35. Strongyloides stercoralis hyperinfection in a patient with angioimmunoblastic lymphadenopathy. Uwaydah, A.K., al Qadah, F. Postgraduate medical journal. (1992) [Pubmed]
  36. Opportunistic infections with Strongyloides stercoralis in renal transplantation. DeVault, G.A., King, J.W., Rohr, M.S., Landreneau, M.D., Brown, S.T., McDonald, J.C. Rev. Infect. Dis. (1990) [Pubmed]
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