Disease relevance of Hypesthesia

• We have treated nine patients suffering from severe occipital pain with associated C2 hypesthesia, unilateral retro-orbital pain, and occipital or C2 tubercle trigger points by intradurally sectioning the C1-C4 dorsal rootlets (C4 if shoulder pain existed) [1].
• Quantitative sensory testing revealed that pain induced by intracutaneous capsaicin injection elicited secondary hyperalgesia coexisting with secondary tactile hypoesthesia [2].
• The reduced sensation of dyspnea during exercise by inhaled oxitropium bromide in severe COPD patients [3].
• Temporal arteritis was suspected and prednisolone started with prompt resolution of the headache, chin hypoesthesia, ESR, and CRP [4].
• These included 16 patients with hypesthesia of the infraorbital nerve, 5 patients with sinusitis, 3 patients who had incomplete decompression, 2 patients with oral antral fistulae, and 1 patient who had CSF rhinorrhea [5].

Psychiatry related information on Hypesthesia

• This patient responded well to nearly 1 g of propranolol daily with a decrease in her drinking behavior, reduced sensation of thirst, and a reduction in her delusional thinking [6].

High impact information on Hypesthesia

• Recent clinical trials indicated that an inhibitor of aldose reductase (AR), the rate-limiting enzyme in the polyol pathway, significantly improved hypesthesia in diabetic patients [7].
• The most common adverse events related to amprenavir were headache, nausea, and hypesthesia [8].
• This unilateral absence of pain was not related to the hypoesthesia that was caused by the operation, and it was associated with a decrease in vascular responses (histamine-induced facial flushing and increase in temperature) on the side operated on [9].
• Neurological examination disclosed chin hypoesthesia while investigations showed a normocytic anemia, ESR of 100, and CRP of 72 [4].
• CLINICAL PRESENTATION: A young man presented with subacute left facial hypesthesia and chronic asymmetrical sensorineural hearing loss [10].

Chemical compound and disease context of Hypesthesia

• This finding suggests that, contrary to the general belief, persistent hypesthesia after glycerol rhizolysis is a negative indicator of long-term success [11].
• We present a case of glove and stocking hypoesthesia, weakness of the flexor muscle of the right great toe, palpable thickening of the right popliteal nerve, and hypoesthetic but normal-appearing areas on the back, which developed in a Trinidadian immigrant who lived in Canada for 16 years [12].
• Fifteen minutes after the injection of 10 ml mepivacaine, the dermatome levels of hypesthesia to cold and pinprick were determined by an individual blinded to the saline volume [13].
• The effect of corneal hypesthesia on the duration of proparacaine anesthetic eyedrops [14].
• PURPOSE: To determine whether substance P concentrations in tears reflect corneal hypesthesia [15].

Biological context of Hypesthesia

• Subjects were also subgrouped into three groups (normal, insulin resistance, and diabetes) according to glucose metabolic status, and those with hypoesthesia at each frequency were excluded in the analyses [16].

Anatomical context of Hypesthesia

• These abnormalities confirm clinical disturbance (hypesthesia of the trigeminal nerve area) and open debate about the real mechanism of trichloroethylene neurotoxicity [17].
• On examination she had hypoesthesia below the C6 vertebra with anesthesia below D3, and absent joint position and vibration sensations [18].
• A 44-year-old woman presented with a thoracic chordoma with intrathoracic extension manifesting as complaints of lower extremity weakness, hypesthesia below the levels of T5-6, and sphincter incontinence [19].
• CONCLUSIONS: This animal model exhibits all the features of human carpal tunnel syndrome, including impaired sensation, motor weakness, and decreased median nerve conduction velocity [20].

Gene context of Hypesthesia

• RESULTS: ANOVA revealed significantly (p < .05) reduced perceptual threshold values (hypoesthesia) for warm, cold, and vibratory sensation in the SCI group [21].
• Two patients treated in a phase I trial of oral 5-FU, leucovorin and eniluracil, an inhibitor of dihydropyrimidine dehydrogenase (DPD), developed delayed onset symptoms of unsteady gait and reduced sensation in the legs [22].
• There was only a trend without statistical significance in interval pain and trigeminal hypoesthesia, more frequent in MS population [23].
• Complications attributed to the surgery included: acquired strabismus (two transient, one permanent) and infraorbital hypesthesia (one transient, one permanent) [24].
• Neurological examination showed right leg weakness and hypesthesia below the T10 level [25].

Analytical, diagnostic and therapeutic context of Hypesthesia

• The TRAM flap has become the gold standard in breast reconstruction but suffers from the disadvantages of poor color match, different texture, and impaired sensation compared to the normal breast [26].

References