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Disease relevance of Sphygmomanometers

  • Dilazep (0.2 mg/kg body weight by IV infusion for ten minutes) significantly reduced systolic and diastolic blood pressure (random-zero sphygmomanometer) on average by 13.3 and 10.6 mm Hg respectively [1].
  • ABPM was performed using the Quiet Trak 98 model by Welch Allyn automatic auscultatory sphygmomanometer for a 24-hour period, for those with clinic documented hypertension [2].
  • More patients had systolic orthostatic hypotension (SBP fall > or =20 mmHg on standing) measured by the sphygmomanometer during the late than early phase (19 [22%] vs 6 [7%]; respectively, p=0.009), but not when measured by the monitor (10 [12%] vs 9 [11%], respectively) [3].

Psychiatry related information on Sphygmomanometers


High impact information on Sphygmomanometers

  • Measured by a conventional sphygmomanometer, systolic and diastolic blood pressures fell significantly in patients who received diltiazem, whereas no consistent changes occurred in those who received placebo [5].
  • Compared with wild-type controls, systolic blood pressure measured by tail cuff sphygmomanometer was reduced by 12 mmHg (1 mmHg = 133 Pa) in Agtr1A(+/-) mice and by 24 mmHg in Agtr1A(-/-) mice [6].
  • RESULTS: By clinical sphygmomanometer measurements at the end of the 24-hour or 12-hour dosing intervals (trough), all three losartan dosages were significantly more effective than placebo at decreasing systolic and diastolic blood pressures [7].
  • Endothelial cell function in Type 1 (insulin-dependent) diabetic patients, both with and without retinopathy, was assessed by measuring the plasma fibrinolytic activity and fibronectin after 10 min venous stasis induced by a sphygmomanometer cuff [8].
  • METHODS : In 32 patients treated with calcineurin inhibitors (RTX-CI, cyclosporine n = 16, tacrolimus n = 16) mean arterial pressure (MAP, automatic sphygmomanometer), muscle sympathetic nerve activity (MSNA, microneurography) and distensibility coefficients of the brachial and carotid arteries (pulsed Doppler) were measured [9].

Biological context of Sphygmomanometers

  • DESIGN: A retrospective analysis of six simultaneous blood pressure measurements in 106 IDDM patients aged 32.6+/-12.0 years (mean +/- SD) and 92 healthy control subjects aged 27.1+/-8.9 years with the SpaceLabs device and a sphygmomanometer [10].
  • Blood pressure and heart rate were determined every 2-4 h using an automatic sphygmomanometer during an abrupt cessation of the previous beta-adrenoceptor blocking drug and commencement of treatment with enalapril 20 mg o.d. 12 h later [11].

Associations of Sphygmomanometers with chemical compounds


Gene context of Sphygmomanometers

  • DESIGN AND METHODS: In a population survey we measured SBP and DBP (using the London School of Hygiene sphygmomanometer) and fasting levels of serum catecholamines, serum insulin and insulin sensitivity in 383 randomly recruited subjects (mean age 25.0 years) of both sexes [17].
  • CONCLUSION: Limits of agreement between the SpaceLabs 90207 device and the sphygmomanometer differ between IDDM patients and healthy controls [10].
  • Seated systolic BP (SBP) and diastolic BP (DBP) were measured using a standard mercury sphygmomanometer [18].
  • Patient, observer and instrument variation in the measurement of strength of shoulder abductor muscles in patients with rheumatoid arthritis using a modified sphygmomanometer [19].
  • Similarly, temporary closure of the A-V access by a sphygmomanometer in eight patients with PHT resulted in a transient decrease in CO (from 6.4+/-0.6 to 5.3+/- 0.5 l/min, P = 0.18) and systolic PAP (from 47.2+/-3.8 to 34.6+/-2.8 mmHg, P<0.028) [20].

Analytical, diagnostic and therapeutic context of Sphygmomanometers


  1. Intravenous dilazep reduces blood pressure and peripheral vascular resistance in humans. Poggesi, L., Masotti, G., Serneri, G.G., Carnovali, M. Journal of clinical pharmacology. (1988) [Pubmed]
  2. The role of ambulatory blood pressure measurements in adolescence and young adults. Al-Hermi, B., Abbas, B. Transplant. Proc. (2004) [Pubmed]
  3. Orthostatic blood pressure changes on prolonged standing in elderly hospital in-patients. Fotherby, M., Iqbal, P., Potter, J. Blood Press. (1997) [Pubmed]
  4. Childhood obesity elevates blood pressure and total cholesterol independent of physical activity. McMurray, R.G., Harrel, J.S., Levine, A.A., Gansky, S.A. Int. J. Obes. Relat. Metab. Disord. (1995) [Pubmed]
  5. Characterization of antihypertensive therapy by whole-day blood pressure monitoring. Weber, M.A., Cheung, D.G., Graettinger, W.F., Lipson, J.L. JAMA (1988) [Pubmed]
  6. Regulation of blood pressure by the type 1A angiotensin II receptor gene. Ito, M., Oliverio, M.I., Mannon, P.J., Best, C.F., Maeda, N., Smithies, O., Coffman, T.M. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  7. Blood pressure effects of the angiotensin II receptor blocker, losartan. Weber, M.A., Byyny, R.L., Pratt, J.H., Faison, E.P., Snavely, D.B., Goldberg, A.I., Nelson, E.B. Arch. Intern. Med. (1995) [Pubmed]
  8. Abnormal endothelial release of fibrinolytic activity and fibronectin in diabetic microangiopathy. Haitas, B., Barnes, A.J., Cederholm-Williams, S.A., Moore, J., Shogry, M.E., Turner, R.C. Diabetologia (1984) [Pubmed]
  9. Relationship between muscle sympathetic nerve activity and large artery mechanical vessel wall properties in renal transplant patients. Kosch, M., Barenbrock, M., Kisters, K., Rahn, K.H., Hausberg, M. J. Hypertens. (2002) [Pubmed]
  10. Determinants of the limits of agreement between the sphygmomanometer and the SpaceLabs 90207 device for blood pressure measurement in health volunteers and insulin-dependent diabetic patients. van Ittersum, F.J., Wijering, R.M., Lambert, J., Donker, A.J., Stehouwer, C.D. J. Hypertens. (1998) [Pubmed]
  11. Abrupt change from a beta-adrenoceptor blocking drug to enalapril in hypertension. Lilja, M., Ikäheimo, M., Juustila, H., Pirttiaho, H., Pakarinen, A., Leppäluoto, J., Jounela, A.J., Ruskoaho, H. J. Intern. Med. (1989) [Pubmed]
  12. Efficacy of an angiotensin II receptor antagonist in managing hyperaldosteronism. Stokes, G.S., Monaghan, J.C., Ryan, M., Woodward, M. J. Hypertens. (2001) [Pubmed]
  13. Factors related to total cholesterol and blood pressure in British 9 year olds. Rona, R.J., Qureshi, S., Chinn, S. Journal of epidemiology and community health. (1996) [Pubmed]
  14. Oscillometric finger blood pressure versus brachial auscultative blood pressure recording. Iyriboz, Y. The Journal of family practice. (1990) [Pubmed]
  15. Indirect blood pressure and heart rate measured quickly without observer bias using a semi-automatic machine (auto-manometer)--response to isometric exercise in normal healthy males and its modification by beta-adrenoceptor blockade. Nyberg, G. British journal of clinical pharmacology. (1977) [Pubmed]
  16. Medical emergencies aboard commercial aircraft. Rodenberg, H. Annals of emergency medicine. (1987) [Pubmed]
  17. The importance of adrenaline, insulin and insulin sensitivity as determinants for blood pressure in young Danes. Clausen, J.O., Ibsen, H., Dige-Petersen, H., Borch-Johnsen, K., Pedersen, O. J. Hypertens. (1995) [Pubmed]
  18. Resting blood pressure and bone mineral content are inversely related in overweight and obese Hispanic women. Afghani, A., Johnson, C.A. Am. J. Hypertens. (2006) [Pubmed]
  19. Patient, observer and instrument variation in the measurement of strength of shoulder abductor muscles in patients with rheumatoid arthritis using a modified sphygmomanometer. Helewa, A., Goldsmith, C.H., Smythe, H.A. J. Rheumatol. (1986) [Pubmed]
  20. The pathogenesis of pulmonary hypertension in haemodialysis patients via arterio-venous access. Nakhoul, F., Yigla, M., Gilman, R., Reisner, S.A., Abassi, Z. Nephrol. Dial. Transplant. (2005) [Pubmed]
  21. Comparison of intra-articular methotrexate with intra-articular triamcinolone hexacetonide by thermography. Bird, H.A., Ring, E.F., Daniel, R., Bacon, P.A. Current medical research and opinion. (1977) [Pubmed]
  22. Euglobulin lysis times: an update. Glassman, A., Abram, M., Baxter, G., Swett, A. Ann. Clin. Lab. Sci. (1993) [Pubmed]
  23. The accuracy of the Marshall 85 oscillometric sphygmomanometer in the ambulatory care setting. Bradley, J.G., Dorsch, J.N., Kallail, K.J., Chaney, E.J., Haskins, R.J., Streit, J.G. The Journal of the American Board of Family Practice / American Board of Family Practice. (1989) [Pubmed]
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