Disease relevance of Lepidium

• The toxicities of copper, chromium, cadmium, nickel, manganese, zinc, and lead ions and various concentrations of mixtures of them were studied using the aquatic plant Spirodela polyrrhiza and the terrestrial plant Lepidium sativum [1].

Psychiatry related information on Lepidium

• However, arginine, yohimbine, Panax ginseng, Maca, and Ginkgo biloba all have some degree of evidence they may be helpful for erectile dysfunction [2].

High impact information on Lepidium

• Using synthetic deoxy-glucotropaeolins (6d-GTL, 4d- GTL, 3d-GTL, 2d-GTL) as substrates, myrosinase activity was studied in comparison to that determined on native glucotropaeolin (GTL) isolated from ripe Lepidium sativum seeds [3].
• Two glass microelectrodes were inserted from opposite sides of the root cap into statocytes of Lepidium sativum L. immersed in medium with or without cytochalasin D (CD) [4].
• Serum levels of luteinizing hormone, follicle-stimulating hormone, prolactin, 17-alpha hydroxyprogesterone, testosterone and 17-beta estradiol were measured before and at 2, 4, 8 and 12 weeks of treatment with placebo or Maca (1.5 g or 3.0 g per day) [5].
• Evomonoside: the cytotoxic cardiac glycoside from Lepidium apetalum [6].
• In order to examine a possible role of calcium in graviperception, the calcium ionophore A23187 was used to elevate the concentration of free cytoplasmic calcium in statocytes of the roots of Lepidium sativum L [7].

Associations of Lepidium with chemical compounds

• Since prostaglandins inhibit the proliferation of CTC in response to PHA or IL-2 (R.D. Maca (1983) Immunopharmacology 6:267), studies were undertaken to determine if the observed inhibition was mediated by effects of F5 on prostaglandin E2 (PGE2) [8].
• Imidazole alkaloids from Lepidium meyenii [9].
• A study with plants revealed no effect of HCFC-141b on seed germination and growth of wheat (Triticum aestivum), radish (Raphanus sativus), and cress (Lepidium sativum) [10].
• The tubers of Lepidium meyenii contain the benzylated derivative of 1,2-dihydro-N-hydroxypyridine, named macaridine, together with the benzylated alkamides (macamides), N-benzyl-5-oxo-6E,8E-octadecadienamide and N-benzylhexadecanamide, as well as the acyclic keto acid, 5-oxo-6E,8E-octadecadienoic acid [11].
• The use of Lepidium sativum in a plant bioassay system for the detection of microcystin-LR [12].

Gene context of Lepidium

• The essential oil profile of maca (Lepidium meyenii) obtained from Lima, Peru, was examined [13].
• Their effects on the germination and growth of the dicots Lactuca sativa (cv. Nigra and cv. Roman), Lepidium sativum, and Lycopersicon esculentum and the monocots Allium cepa, Hordeum vulgare, and Triticum aestivum as standard target species have been studied [14].
• This study aimed at testing the hypothesis that Maca contains testosterone-like compounds, able to bind the human androgen receptor and promote transcription pathways regulated by steroid hormone signaling [15].
• METHODS: Mice were treated with 80 mg/kg of malathion in the presence or absence of an aqueous extract of Maca, which was orally administered 7, 14 or 21 days after injection of the malathion [16].

Analytical, diagnostic and therapeutic context of Lepidium

• These increases by TE were reduced after treatment with Red Maca for 42 days [17].

References