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Disease relevance of Impotence


Psychiatry related information on Impotence


High impact information on Impotence


Chemical compound and disease context of Impotence


Biological context of Impotence


Anatomical context of Impotence


Gene context of Impotence


Analytical, diagnostic and therapeutic context of Impotence


  1. Treatment of men with erectile dysfunction with transurethral alprostadil. Medicated Urethral System for Erection (MUSE) Study Group. Padma-Nathan, H., Hellstrom, W.J., Kaiser, F.E., Labasky, R.F., Lue, T.F., Nolten, W.E., Norwood, P.C., Peterson, C.A., Shabsigh, R., Tam, P.Y. N. Engl. J. Med. (1997) [Pubmed]
  2. Erectile dysfunction in spina bifida is treatable. Palmer, J.S., Kaplan, W.E., Firlit, C.F. Lancet (1999) [Pubmed]
  3. Prospective pilot study of sildenafil for treatment of postradiotherapy erectile dysfunction in patients with prostate cancer. Weber, D.C., Bieri, S., Kurtz, J.M., Miralbell, R. J. Clin. Oncol. (1999) [Pubmed]
  4. Sildenafil citrate for the treatment of erectile dysfunction in men with Type II diabetes mellitus. Boulton, A.J., Selam, J.L., Sweeney, M., Ziegler, D. Diabetologia (2001) [Pubmed]
  5. Efficacy of oral sildenafil in hemodialysis patients with erectile dysfunction. Seibel, I., Poli De Figueiredo, C.E., Telöken, C., Moraes, J.F. J. Am. Soc. Nephrol. (2002) [Pubmed]
  6. Treatment of erectile dysfunction in men with depressive symptoms: results of a placebo-controlled trial with sildenafil citrate. Seidman, S.N., Roose, S.P., Menza, M.A., Shabsigh, R., Rosen, R.C. The American journal of psychiatry. (2001) [Pubmed]
  7. Is quality of life different for men with erectile dysfunction and prostate cancer compared to men with erectile dysfunction due to other causes? Results from the ExCEED data base. Penson, D.F., Latini, D.M., Lubeck, D.P., Wallace, K., Henning, J.M., Lue, T. J. Urol. (2003) [Pubmed]
  8. Oral trazodone as empirical therapy for erectile dysfunction: a retrospective review. Lance, R., Albo, M., Costabile, R.A., Steers, W.D. Urology (1995) [Pubmed]
  9. Comparison between sildenafil-treated subjects with erectile dysfunction and control subjects on the Self-Esteem And Relationship questionnaire. Cappelleri, J.C., Bell, S.S., Althof, S.E., Siegel, R.L., Stecher, V.J. The journal of sexual medicine. (2006) [Pubmed]
  10. Commentary: pharmacological agents for erectile dysfunction and the human sexual response cycle. Perelman, M.A. Journal of sex & marital therapy. (1998) [Pubmed]
  11. Sildenafil in the treatment of erectile dysfunction. Meikle, A.W., Arver, S. N. Engl. J. Med. (1998) [Pubmed]
  12. Antagonism of Rho-kinase stimulates rat penile erection via a nitric oxide-independent pathway. Chitaley, K., Wingard, C.J., Clinton Webb, R., Branam, H., Stopper, V.S., Lewis, R.W., Mills, T.M. Nat. Med. (2001) [Pubmed]
  13. Sildenafil for treatment of erectile dysfunction in men with diabetes: a randomized controlled trial. Sildenafil Diabetes Study Group. Rendell, M.S., Rajfer, J., Wicker, P.A., Smith, M.D. JAMA (1999) [Pubmed]
  14. Decrease of vasoactive intestinal polypeptide (VIP) in the penises from impotent men. Gu, J., Polak, J.M., Lazarides, M., Morgan, R., Pryor, J.P., Marangos, P.J., Blank, M.A., Bloom, S.R. Lancet (1984) [Pubmed]
  15. Propranolol erectile dysfunction relieved. Bathen, J. Ann. Intern. Med. (1978) [Pubmed]
  16. Erectile dysfunction in cyclic GMP-dependent kinase I-deficient mice. Hedlund, P., Aszodi, A., Pfeifer, A., Alm, P., Hofmann, F., Ahmad, M., Fassler, R., Andersson, K.E. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  17. Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats. Brioni, J.D., Moreland, R.B., Cowart, M., Hsieh, G.C., Stewart, A.O., Hedlund, P., Donnelly-Roberts, D.L., Nakane, M., Lynch, J.J., Kolasa, T., Polakowski, J.S., Osinski, M.A., Marsh, K., Andersson, K.E., Sullivan, J.P. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  18. Bicalutamide monotherapy versus flutamide plus goserelin in prostate cancer patients: results of an Italian Prostate Cancer Project study. Boccardo, F., Rubagotti, A., Barichello, M., Battaglia, M., Carmignani, G., Comeri, G., Conti, G., Cruciani, G., Dammino, S., Delliponti, U., Ditonno, P., Ferraris, V., Lilliu, S., Montefiore, F., Portoghese, F., Spano, G. J. Clin. Oncol. (1999) [Pubmed]
  19. No adverse hemodynamic interaction between sildenafil and red wine. Leslie, S.J., Atkins, G., Oliver, J.J., Webb, D.J. Clin. Pharmacol. Ther. (2004) [Pubmed]
  20. Testosterone replacement therapy and sleep-related erections in hypogonadal men. Cunningham, G.R., Hirshkowitz, M., Korenman, S.G., Karacan, I. J. Clin. Endocrinol. Metab. (1990) [Pubmed]
  21. Effect of sildenafil citrate on blood pressure and heart rate in men with erectile dysfunction taking concomitant antihypertensive medication. Sildenafil Study Group. Zusman, R.M., Prisant, L.M., Brown, M.J. J. Hypertens. (2000) [Pubmed]
  22. Pharmacokinetics of prostaglandin E1 and its main metabolites after intracavernous injection and short-term infusion of prostaglandin E1 in patients with erectile dysfunction. Cawello, W., Schweer, H., Dietrich, B., Seyberth, H.W., Albrecht, D., Fox, A., Hohmuth, H. J. Urol. (1997) [Pubmed]
  23. Sildenafil response is influenced by the G protein beta 3 subunit GNB3 C825T polymorphism: a pilot study. Sperling, H., Eisenhardt, A., Virchow, S., Hauck, E., Lenk, S., Porst, H., Stief, C., Wetterauer, U., Rubben, H., Muller, N., Siffert, W. J. Urol. (2003) [Pubmed]
  24. Randomized trial of sildenafil for the treatment of erectile dysfunction in spinal cord injury. Sildenafil Study Group. Giuliano, F., Hultling, C., El Masry, W.S., Smith, M.D., Osterloh, I.H., Orr, M., Maytom, M. Ann. Neurol. (1999) [Pubmed]
  25. The effect of vardenafil, a potent and highly selective phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction, on the cardiovascular response to exercise in patients with coronary artery disease. Thadani, U., Smith, W., Nash, S., Bittar, N., Glasser, S., Narayan, P., Stein, R.A., Larkin, S., Mazzu, A., Tota, R., Pomerantz, K., Sundaresan, P. J. Am. Coll. Cardiol. (2002) [Pubmed]
  26. Effect of phosphodiesterase-5 inhibitor, sildenafil (Viagra), in animal models of airways disease. Toward, T.J., Smith, N., Broadley, K.J. Am. J. Respir. Crit. Care Med. (2004) [Pubmed]
  27. Preliminary results with the nitric oxide donor linsidomine chlorhydrate in the treatment of human erectile dysfunction. Stief, C.G., Holmquist, F., Djamilian, M., Krah, H., Andersson, K.E., Jonas, U. J. Urol. (1992) [Pubmed]
  28. Expression of Rho-kinase and its functional role in the contractile activity of the mouse vas deferens. Büyükafşar, K., Levent, A., Ark, M. Br. J. Pharmacol. (2003) [Pubmed]
  29. Platelet-derived growth factor (PDGF) and PDGF receptors in rat corpus cavernosum: changes in expression after transient in vivo hypoxia. Aversa, A., Basciani, S., Visca, P., Arizzi, M., Gnessi, L., Frajese, G., Fabbri, A. J. Endocrinol. (2001) [Pubmed]
  30. 3',5'-cyclic nucleotide phosphodiesterase 11A: localization in human tissues. Loughney, K., Taylor, J., Florio, V.A. Int. J. Impot. Res. (2005) [Pubmed]
  31. Molecular biological characterization of phosphodiesterase 3A from human corpus cavernosum. Küthe, A., Eckel, H., Stief, C.G., Uckert, S., Forssmann, W.G., Jonas, U., Mägert, H.J. Chem. Biol. Interact. (1999) [Pubmed]
  32. Sulfation of apomorphine by human sulfotransferases: evidence of a major role for the polymorphic phenol sulfotransferase, SULT1A1. Thomas, N.L., Coughtrie, M.W. Xenobiotica (2003) [Pubmed]
  33. Arginase-boronic acid complex highlights a physiological role in erectile function. Cox, J.D., Kim, N.N., Traish, A.M., Christianson, D.W. Nat. Struct. Biol. (1999) [Pubmed]
  34. Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group. Goldstein, I., Lue, T.F., Padma-Nathan, H., Rosen, R.C., Steers, W.D., Wicker, P.A. N. Engl. J. Med. (1998) [Pubmed]
  35. Sildenafil for male erectile dysfunction: a systematic review and meta-analysis. Fink, H.A., Mac Donald, R., Rutks, I.R., Nelson, D.B., Wilt, T.J. Arch. Intern. Med. (2002) [Pubmed]
  36. Combined technetium radioisotope penile plethysmography and xenon washout: a technique for evaluating corpora cavernosal inflow and outflow during early tumescence. Schwartz, A.N., Graham, M.M. J. Nucl. Med. (1991) [Pubmed]
  37. Safety and efficacy of vardenafil for the treatment of men with erectile dysfunction after radical retropubic prostatectomy. Brock, G., Nehra, A., Lipshultz, L.I., Karlin, G.S., Gleave, M., Seger, M., Padma-Nathan, H. J. Urol. (2003) [Pubmed]
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