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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Amphipoda

  • Although chlorfenapyr remained in sediment, TWAs concentrations from the microcosm study along with model-predicted concentrations indicate low hazard to benthic invertebrate species based on acute toxicity to amphipods in the laboratory [1].

High impact information on Amphipoda

  • For amphipods collected from microcosms exposed to the herbicide 2-[4-(2,4-dichlorophenoxy)phenoxy]propionic acid methyl ester (diclofop-methyl, trade name Hoe Grass), there were detectable levels of only the hydrolysis product, diclofop acid, in the lipid-rich tissue [2].
  • Mitochondrial (mt) sequences from cytochrome oxidase subunit I to the subunit II gene (COI, COII) were analysed in crustacean talitrid amphipods [3].
  • The greater sensitivity of C. tentans to fluoranthene as compared to the amphipods may be due, in part, to a potential toxic metabolite [4].
  • Despite the inhibition of major antioxidant enzymes, the studied amphipods were able to successfully resist the NOM oxidative impact and, at low NOM concentrations, to combat lipid peroxidation processes [5].
  • The amphipods significantly avoided petri dishes with the three highest concentrations of zinc pyrithione and the calculated EC(50) was 9.65microgL(-1) sediment [6].

Chemical compound and disease context of Amphipoda


Biological context of Amphipoda


Associations of Amphipoda with chemical compounds

  • In the 10-day experiment, where amphipods did not receive supplemental food, growth was significantly increased in DDT treatments where survival was not affected [11].
  • Validation of estuarine gammarid collectives (Amphipoda: Crustacea) as biomonitors for cadmium in semi-controlled toxicokinetic flow-through experiments [12].
  • Consistent effects were observed at the highest exposure concentrations (400 microg DDD/goc [DDD concentrations normalized to grams of organic carbon (goc) in sediment] or 4% GCR sediment) on survival, length, and reproduction of amphipods in the laboratory and on abundance of invertebrates colonizing sediments in the field [13].
  • Amphipods contained greater concentrations than mysids of PCB, DDT residues, and toxaphene, possibly reflecting differences in habitat (benthic vs epibenthic) and diet (detritus vs plankton) [14].
  • Influences of sedimentary organic matter quality on the bioaccumulation of 4-nonylphenol by estuarine amphipods [15].

Gene context of Amphipoda

  • Amphipods of Diporeia spp. have declined considerably during the last decade in the Great Lakes. We examined the possibility that disease may be affecting these populations [16].
  • The activities of antioxidant enzymes peroxidase, catalase and glutathione-S-transferase were measured in different sections (tagmata) of the amphipods' bodies as well as in different size groups [17].

Analytical, diagnostic and therapeutic context of Amphipoda

  • Laboratory bioassays were performed to obtain data on the lethal effects of nitrite to three species of freshwater invertebrates: the planarian Polycelis felina and the amphipods Echinogammarus echinosetosus and Eulimnogammarus toletanus [18].


  1. Fate and effects of the insecticide-miticide chlorfenapyr in outdoor aquatic microcosms. Rand, G.M. Ecotoxicol. Environ. Saf. (2004) [Pubmed]
  2. Tandem mass spectrometry of herbicide residues in lipid-rich tissue. Headley, J.V., Peru, K.M., Arts, M.T. Anal. Chem. (1995) [Pubmed]
  3. Mitochondrial COI-NC-COII sequences in talitrid amphipods (Crustacea). Davolos, D., Maclean, N. Heredity (2005) [Pubmed]
  4. Time-dependent toxicity of fluoranthene to freshwater invertebrates and the role of biotransformation on lethal body residues. Schuler, L.J., Landrum, P.F., Lydy, M.J. Environ. Sci. Technol. (2004) [Pubmed]
  5. Specific antioxidant reactions to oxidative stress promoted by natural organic matter in two amphipod species from Lake Baikal. Timofeyev, M.A., Shatilina, Z.M., Kolesnichenko, A.V., Kolesnichenko, V.V., Steinberg, C.E. Environ. Toxicol. (2006) [Pubmed]
  6. Avoidance response of sediment living amphipods to zinc pyrithione as a measure of sediment toxicity. Eriksson Wiklund, A.K., Börjesson, T., Wiklund, S.J. Mar. Pollut. Bull. (2006) [Pubmed]
  7. Toxicity and bioaccumulation of DDT in freshwater amphipods in exposures to spiked sediments. Lotufo, G.R., Landrum, P.F., Gedeon, M.L. Environ. Toxicol. Chem. (2001) [Pubmed]
  8. Acute toxicity of sodium selenate to two daphnids and three amphipods. Brix, K.V., Henderson, D.G., Adams, W.J., Reash, R.J., Carlton, R.G., McIntyre, D.O. Environ. Toxicol. (2001) [Pubmed]
  9. Acute toxicity of methyl-parathion in wetland mesocosms: assessing the influence of aquatic plants using laboratory testing with Hyalella azteca. Schulz, R., Moore, M.T., Bennett, E.R., Milam, C.D., Bouldin, J.L., Farris, J.L., Smith, S., Cooper, C.M. Arch. Environ. Contam. Toxicol. (2003) [Pubmed]
  10. Bisphenol A in artificial indoor streams: II. Stress response and gonad histology in Gammarus fossarum (Amphipoda). Schirling, M., Jungmann, D., Ladewig, V., Ludwichowski, K.U., Nagel, R., Köhler, H.R., Triebskorn, R. Ecotoxicology (2006) [Pubmed]
  11. DDT toxicity and critical body residue in the amphipod Leptocheirus plumulosus in exposures to spiked sediment. Lotufo, G.R., Farrar, J.D., Duke, B.M., Bridges, T.S. Arch. Environ. Contam. Toxicol. (2001) [Pubmed]
  12. Validation of estuarine gammarid collectives (Amphipoda: Crustacea) as biomonitors for cadmium in semi-controlled toxicokinetic flow-through experiments. Zauke, G.P., von Lemm, R., Meurs, H.G., Butte, W. Environ. Pollut. (1995) [Pubmed]
  13. A field assessment of long-term laboratory sediment toxicity tests with the amphipod Hyalella azteca. Ingersoll, C.G., Wang, N., Hayward, J.M., Jones, J.R., Jones, S.B., Ireland, D.S. Environ. Toxicol. Chem. (2005) [Pubmed]
  14. The biomagnification of polychlorinated biphenyls, toxaphene, and DDT compounds in a Lake Michigan offshore food web. Evans, M.S., Noguchi, G.E., Rice, C.P. Arch. Environ. Contam. Toxicol. (1991) [Pubmed]
  15. Influences of sedimentary organic matter quality on the bioaccumulation of 4-nonylphenol by estuarine amphipods. Hecht, S.A., Gunnarsson, J.S., Boese, B.L., Lamberson, J.O., Schaffner, C., Giger, W., Jepson, P.C. Environ. Toxicol. Chem. (2004) [Pubmed]
  16. Prevalence of parasites in amphipods Diporeia spp. from Lakes Michigan and Huron, USA. Messick, G.A., Overstreet, R.M., Nalepa, T.F., Tyler, S. Dis. Aquat. Org. (2004) [Pubmed]
  17. Antioxidant enzyme activity in endemic Baikalean versus Palaearctic amphipods: tagma- and size-related changes. Timofeyev, M.A. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. (2006) [Pubmed]
  18. Toxicity of nitrite to three species of freshwater invertebrates. Alonso, A., Camargo, J.A. Environ. Toxicol. (2006) [Pubmed]
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