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MeSH Review

Pituitary-Adrenal System

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Disease relevance of Pituitary-Adrenal System


High impact information on Pituitary-Adrenal System


Biological context of Pituitary-Adrenal System


Anatomical context of Pituitary-Adrenal System


Associations of Pituitary-Adrenal System with chemical compounds


Gene context of Pituitary-Adrenal System

  • We conclude that AVP has an important role in stress-induced activation of the pituitary-adrenal system, possibly by potentiating the effects of CRF [18].
  • Graded doses arginine-vasopressin (AVP) were administered to depressed patients and control subjects to compare the sensitivity of the pituitary-adrenal system of these subjects for this compound [19].
  • Serum corticosteroid-binding globulin (CBG) concentrations were measured by a radioligand method in rats under the action of some factors influencing activity of pituitary-adrenal system [20].
  • To evaluate the immediate effect of exposure to a high level of noise on the sympatho-adrenal and pituitary-adrenal systems, measurements were made of circulating catecholamines, growth hormone, ACTH, and cortisol in seven normal male subjects [21].
  • We suggest that low cortisol levels that appear during LAR are not principally due to any dysfunction in the pituitary adrenal system [22].

Analytical, diagnostic and therapeutic context of Pituitary-Adrenal System


  1. Neuroendocrinology of acute immunity. Reichlin, S. J. Endocrinol. Invest. (2004) [Pubmed]
  2. Elevation of plasma corticosterone by swim stress and insulin-induced hypoglycemia in control and fluoxetine-pretreated rats. Fuller, R.W., Snoddy, H.D. Endocrine research communications. (1977) [Pubmed]
  3. RU 486: a steroid with antiglucocorticosteroid activity that only disinhibits the human pituitary-adrenal system at a specific time of day. Gaillard, R.C., Riondel, A., Muller, A.F., Herrmann, W., Baulieu, E.E. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  4. A functional anatomical analysis of central pathways subserving the effects of interleukin-1 on stress-related neuroendocrine neurons. Ericsson, A., Kovács, K.J., Sawchenko, P.E. J. Neurosci. (1994) [Pubmed]
  5. Adrenergic mechanisms involved in the control of pituitary-adrenal activity in the rat: a beta-adrenergic stimulatory mechanism. Tilders, F.J., Berkenbosch, F., Smelik, P.G. Endocrinology (1982) [Pubmed]
  6. Antagonistic effects of adrenalectomy and ether/surgical stress on light-induced photoreceptor damage. O'Steen, W.K., Donnelly, J.E. Invest. Ophthalmol. Vis. Sci. (1982) [Pubmed]
  7. Diazepam-like effects of a fish protein hydrolysate (Gabolysat PC60) on stress responsiveness of the rat pituitary-adrenal system and sympathoadrenal activity. Bernet, F., Montel, V., Noël, B., Dupouy, J.P. Psychopharmacology (Berl.) (2000) [Pubmed]
  8. Fluctuation of fetal rat hepatic histidine decarboxylase activity through the glucocorticoid-ACTH system. Ohmori, E., Imanishi, N., Ohgoh, M., Fukui, T., Ichikawa, A. Biochem. Pharmacol. (1991) [Pubmed]
  9. Involvement of the adrenal gland in the suckling-induced decrease in LH and FSH secretion and the concomitant increase in prolactin secretion in the rat. Taya, K., Sasamoto, S. J. Endocrinol. (1990) [Pubmed]
  10. Acute increase in plasma corticosterone level in female mice evoked by pheromones. Marchlewska-Koj, A., Zacharczuk-Kakietek, M. Physiol. Behav. (1990) [Pubmed]
  11. A correlative study between glucocorticoid receptor levels in human mononuclear leukocytes and biochemical data in Cushing's disease. Pardes, E.M., de Yampey, J.W., Soto, R.J., Moses, D.F., De Nicola, A.F. Acta Endocrinol. (1989) [Pubmed]
  12. Mechanisms by which stressful stimuli activate the pituitary-adrenal system. Makara, G.B. Fed. Proc. (1985) [Pubmed]
  13. [3H]dexamethasone binding in the limbic brain of the fetal rat. Meaney, M.J., Sapolsky, R.M., Aitken, D.H., McEwen, B.S. Brain Res. (1985) [Pubmed]
  14. Circadian variation in the sensitivity of the pituitary-adrenal system to dexamethasone suppression. Dunn, J.D., Carrillo, A.J. J. Endocrinol. (1978) [Pubmed]
  15. Inhibitory effects of adrenocorticotrophin or corticosterone on progesterone secretion during mid-pregnancy in rats. Kato, H., Nanjo, K., Numa, F., Nakamura, Y., Ueda, K., Inoguchi, H., Torigoe, T. J. Reprod. Fertil. (1988) [Pubmed]
  16. Regulation of the central nervous system-pituitary-adrenal axis in rats after neonatal treatment with monosodium glutamate. Magariños, A.M., Estivariz, F., Morado, M.I., De Nicola, A.F. Neuroendocrinology (1988) [Pubmed]
  17. Neonatal 6-hydroxydopamine prevents adaptation to chemical disruption of the pituitary-adrenal system in the rat. Bialik, R.J., Pappas, B.A., Roberts, D.C. Hormones and behavior. (1984) [Pubmed]
  18. Role of epinephrine and vasopressin in the control of the pituitary-adrenal response to stress. Tilders, F.J., Berkenbosch, F., Vermes, I., Linton, E.A., Smelik, P.G. Fed. Proc. (1985) [Pubmed]
  19. Stimulation of the pituitary-adrenal axis with a low dose [Arg8]-vasopressin in depressed patients and healthy subjects. Gispen-de Wied, C.C., Westenberg, H.G., Koppeschaar, H.P., Thijssen, J.H., van Ree, J.M. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. (1992) [Pubmed]
  20. Corticosteroid-binding globulin levels in the rat serum under conditions of starvation and restriction of motions. Tinnikov, A.A. Horm. Metab. Res. (1993) [Pubmed]
  21. Plasma catecholamines and pituitary adrenal hormones in response to noise exposure. Follenius, M., Brandenberger, G., Lecornu, C., Simeoni, M., Reinhardt, B. European journal of applied physiology and occupational physiology. (1980) [Pubmed]
  22. Pituitary and adrenal functions during late asthmatic responses. Nakazawa, T., Matsui, S., Saitoh, A., Umegae, Y., Yoshie, Y., Fueki, R., Kobayashi, S. Annals of allergy. (1988) [Pubmed]
  23. Sensitivity of the fetal rat pituitary-adrenal system to corticotropin-releasing factor in organ culture. Yamamoto, M., Arishima, K., Takizawa, T., Shirai, M., Eguchi, Y. Acta anatomica. (1992) [Pubmed]
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