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MeSH Review

Gyrate Atrophy

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Disease relevance of Gyrate Atrophy


High impact information on Gyrate Atrophy


Chemical compound and disease context of Gyrate Atrophy


Biological context of Gyrate Atrophy


Anatomical context of Gyrate Atrophy


Gene context of Gyrate Atrophy


Analytical, diagnostic and therapeutic context of Gyrate Atrophy


  1. Constructing retinal fundus photomontages. A new computer-based method. Mahurkar, A.A., Vivino, M.A., Trus, B.L., Kuehl, E.M., Datiles, M.B., Kaiser-Kupfer, M.I. Invest. Ophthalmol. Vis. Sci. (1996) [Pubmed]
  2. Hyperornithinemia and gyrate atrophy of the choroid and retina. McCulloch, J.C., Arshinoff, S.A., Marliss, E.B., Parker, J.A. Ophthalmology (1978) [Pubmed]
  3. Hereditary retinal dystrophies and choroidal neovascularization. Marano, F., Deutman, A.F., Leys, A., Aandekerk, A.L. Graefes Arch. Clin. Exp. Ophthalmol. (2000) [Pubmed]
  4. Molecular genetic approaches to the analysis of human ophthalmic disease. Cooper, D.N., Jay, M., Bhattacharya, S., Jay, B. Eye (London, England) (1987) [Pubmed]
  5. Vitreochorioretinal degeneration associated with trichomegaly. Fishman, G.A., Fried, W., Jednock, N. Annals of ophthalmology. (1976) [Pubmed]
  6. The skipping of constitutive exons in vivo induced by nonsense mutations. Dietz, H.C., Valle, D., Francomano, C.A., Kendzior, R.J., Pyeritz, R.E., Cutting, G.R. Science (1993) [Pubmed]
  7. Gyrate atrophy of the retina: inborn error of L-ornithin:2-oxoacid aminotransferase. O'Donnell, J.J., Sandman, R.P., Martin, S.R. Science (1978) [Pubmed]
  8. Gyrate atrophy of the choroid and retina with hyperornithinemia. Deficient formation of guanidinoacetic acid from arginine. Sipilä, I., Simell, O., Arjomaa, P. J. Clin. Invest. (1980) [Pubmed]
  9. Vitamin B6 in management of gyrate atrophy of choroid and retina. Weleber, R.G., Kennaway, N.G., Buist, N.R. Lancet (1978) [Pubmed]
  10. Gyrate atrophy of the choroid and retina: amino acid metabolism and correction of hyperornithinemia with an arginine-deficient diet. Valle, D., Walser, M., Brusilow, S.W., Kaiser-Kupfer, M. J. Clin. Invest. (1980) [Pubmed]
  11. Pyridoxine-responsive gyrate atrophy of the choroid and retina: clinical and biochemical correlates of the mutation A226V. Michaud, J., Thompson, G.N., Brody, L.C., Steel, G., Obie, C., Fontaine, G., Schappert, K., Keith, C.G., Valle, D., Mitchell, G.A. Am. J. Hum. Genet. (1995) [Pubmed]
  12. Reduced brain creatine in gyrate atrophy of the choroid and retina with hyperornithinemia. Nänto-Salonen, K., Komu, M., Lundbom, N., Heinänen, K., Alanen, A., Sipilä, I., Simell, O. Neurology (1999) [Pubmed]
  13. Prevention of ornithine cytotoxicity by proline in human retinal pigment epithelial cells. Ueda, M., Masu, Y., Ando, A., Maeda, H., Del Monte, M.A., Uyama, M., Ito, S. Invest. Ophthalmol. Vis. Sci. (1998) [Pubmed]
  14. Atypical gyrate atrophy of the choroid and retina associated with iminoglycinuria. Hayasaka, S., Mizuno, K., Yabata, K., Saito, T., Tada, K. Arch. Ophthalmol. (1982) [Pubmed]
  15. Point mutation affecting processing of the ornithine aminotransferase precursor protein in gyrate atrophy. Inana, G., Chambers, C., Hotta, Y., Inouye, L., Filpula, D., Pulford, S., Shiono, T. J. Biol. Chem. (1989) [Pubmed]
  16. Detection of point mutations associated with genetic diseases by an exon scanning technique. Kaufman, D.L., Ramesh, V., McClatchey, A.I., Menkes, J.H., Tobin, A.J. Genomics (1990) [Pubmed]
  17. The natural history of gyrate atrophy of the choroid and retina. Takki, K.K., Milton, R.C. Ophthalmology (1981) [Pubmed]
  18. Gyrate atrophy of the choroid and retina: improved visual function following reduction of plasma ornithine by diet. Kaiser-Kupfer, M.I., de Monasterio, F.M., Valle, D., Walser, M., Brusilow, S. Science (1980) [Pubmed]
  19. Gyrate atrophy of the choroid and retina: deficiency of ornithine aminotransferase in transformed lymphocytes. Valle, D., Kaiser-Kupfer, M.I., Del Valle, L.A. Proc. Natl. Acad. Sci. U.S.A. (1977) [Pubmed]
  20. Retrovirus-mediated gene transfer of ornithine-delta-aminotransferase into keratinocytes from gyrate atrophy patients. Jensen, T.G., Sullivan, D.M., Morgan, R.A., Taichman, L.B., Nussenblatt, R.B., Blaese, R.M., Csaky, K.G. Hum. Gene Ther. (1997) [Pubmed]
  21. Heterogeneity in ornithine cytotoxicity of bovine retinal pigment epithelial cells in primary culture. Ando, A., Ueda, M., Uyama, M., Masu, Y., Okumura, T., Ito, S. Exp. Eye Res. (2000) [Pubmed]
  22. Molecular basis of ornithine aminotransferase deficiency in B-6-responsive and -nonresponsive forms of gyrate atrophy. Ramesh, V., McClatchey, A.I., Ramesh, N., Benoit, L.A., Berson, E.L., Shih, V.E., Gusella, J.F. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  23. Gyrate atrophy of the choroid and retina: assignment of the ornithine aminotransferase structural gene to human chromosome 10 and mouse chromosome 7. O'Donnell, J.J., Vannas-Sulonen, K., Shows, T.B., Cox, D.R. Am. J. Hum. Genet. (1988) [Pubmed]
  24. A Fukuyama type of congenital muscular dystrophy associated with atypical gyrate atrophy of the choroid and retina. A case report. Mishima, H., Hirata, H., Ono, H., Choshi, K., Nishi, Y., Fukuda, K. Acta ophthalmologica. (1985) [Pubmed]
  25. Immunocytochemical localization of ornithine aminotransferase in rat ocular tissues. Takahashi, O., Ishiguro, S., Mito, T., Hayasaka, S., Shiono, T., Mizuno, K., Ohura, T., Tada, K. Invest. Ophthalmol. Vis. Sci. (1987) [Pubmed]
  26. Hyperornithinemia associated with gyrate atrophy of the choroid and retina in a child with myopia. Shenoi, A., L, N., Christopher, R. Indian pediatrics. (2001) [Pubmed]
  27. Ornithine delta-aminotransferase mutations in gyrate atrophy. Allelic heterogeneity and functional consequences. Brody, L.C., Mitchell, G.A., Obie, C., Michaud, J., Steel, G., Fontaine, G., Robert, M.F., Sipila, I., Kaiser-Kupfer, M., Valle, D. J. Biol. Chem. (1992) [Pubmed]
  28. Gyrate atrophy of the choroid and retina: decreased ornithine aminotransferase concentration in cultured skin fibroblasts from patients. Ohura, T., Kominami, E., Tada, K., Katunuma, N. Clin. Chim. Acta (1984) [Pubmed]
  29. Clinical trials of vitamin B6 and proline supplementation for gyrate atrophy of the choroid and retina. Hayasaka, S., Saito, T., Nakajima, H., Takahashi, O., Mizuno, K., Tada, K. The British journal of ophthalmology. (1985) [Pubmed]
  30. Ocular manifestations of metabolic disorders. Iwata, F., Kaiser-Kupfer, M.I. Current opinion in ophthalmology. (1996) [Pubmed]
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