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Gene Review

Oat  -  ornithine aminotransferase

Mus musculus

Synonyms: AI194874, Ornithine aminotransferase, mitochondrial, Ornithine--oxo-acid aminotransferase, rhg
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  1. Mapping of ornithine aminotransferase gene sequences to mouse chromosomes 7, X, and 3. Ramesh, V., Cheng, S.V., Kozak, C.A., Herron, B.J., Shih, V.E., Taylor, B.A., Gusella, J.F. Mamm. Genome (1992) [Pubmed]
  2. Correction of ornithine accumulation prevents retinal degeneration in a mouse model of gyrate atrophy of the choroid and retina. Wang, T., Steel, G., Milam, A.H., Valle, D. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  3. Catecholamines are required for androgen-induced ODC expression but not for hypertrophy of mouse kidney. Manteuffel-Cymborowska, M., Peska, M., Chmurzyńska, W., Grzelakowska-Sztabert, B. Biochim. Biophys. Acta (1997) [Pubmed]
  4. Protection against lethal ammonia intoxication: synergism between endogenous ornithine and L-carnitine. Sarhan, S., Knoedgen, B., Seiler, N. Metabolic brain disease. (1994) [Pubmed]
  5. Effects of inhibition of ornithine aminotransferase on thioacetamide-induced hepatogenic encephalopathy. Sarhan, S., Knödgen, B., Grauffel, C., Seiler, N. Neurochem. Res. (1993) [Pubmed]
  6. Colocalization in pericentral hepatocytes in adult mice and similarity in developmental expression pattern of ornithine aminotransferase and glutamine synthetase mRNA. Kuo, F.C., Hwu, W.L., Valle, D., Darnell, J.E. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  7. Gyrate atrophy of the choroid and retina: assignment of the ornithine aminotransferase structural gene to human chromosome 10 and mouse chromosome 7. O'Donnell, J.J., Vannas-Sulonen, K., Shows, T.B., Cox, D.R. Am. J. Hum. Genet. (1988) [Pubmed]
  8. Hepatic HNF4alpha deficiency induces periportal expression of glutamine synthetase and other pericentral enzymes. Stanulović, V.S., Kyrmizi, I., Kruithof-de Julio, M., Hoogenkamp, M., Vermeulen, J.L., Ruijter, J.M., Talianidis, I., Hakvoort, T.B., Lamers, W.H. Hepatology (2007) [Pubmed]
  9. A heritable variant of mouse liver ornithine aminotransferase (EC induced by ethylnitrosourea. Giometti, C.S., Tollaksen, S.L., Gemmell, M.A., Burcham, J., Peraino, C. J. Biol. Chem. (1988) [Pubmed]
  10. Compensatory changes in enzymes of arginine metabolism during renal hypertrophy in mice. Natesan, S., Reddy, S.R. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. (2001) [Pubmed]
  11. Ornithine deficiency in the arginase double knockout mouse. Deignan, J.L., Livesay, J.C., Yoo, P.K., Goodman, S.I., O'brien, W.E., Iyer, R.K., Cederbaum, S.D., Grody, W.W. Mol. Genet. Metab. (2006) [Pubmed]
  12. Sequence of the promoter region of the mouse gene encoding ornithine aminotransferase. Shull, J.D., Esumi, N., Colwell, A.S., Pennington, K.L., Jendoubi, M. Gene (1995) [Pubmed]
  13. Localization of the ornithine aminotransferase gene and related sequences on two human chromosomes. Ramesh, V., Eddy, R., Bruns, G.A., Shih, V.E., Shows, T.B., Gusella, J.F. Hum. Genet. (1987) [Pubmed]
  14. Ornithine aminotransferase-related sequences map to two nonadjacent intervals on the human X chromosome short arm. Lafreniere, R.G., Geraghty, M.T., Valle, D., Shows, T.B., Willard, H.F. Genomics (1991) [Pubmed]
  15. Evidence that interaction of hepatocytes with the collecting (hepatic) veins triggers position-specific transcription of the glutamine synthetase and ornithine aminotransferase genes in the mouse liver. Kuo, F.C., Darnell, J.E. Mol. Cell. Biol. (1991) [Pubmed]
  16. A variant of ornithine aminotransferase from mouse small intestine. Lim, S.N., Rho, H.W., Park, J.W., Jhee, E.C., Kim, J.S., Kim, H.R. Exp. Mol. Med. (1998) [Pubmed]
  17. Testosterone down-regulates ornithine aminotransferase gene and up-regulates arginase II and ornithine decarboxylase genes for polyamines synthesis in the murine kidney. Levillain, O., Diaz, J.J., Blanchard, O., Déchaud, H. Endocrinology (2005) [Pubmed]
  18. Arginine and ornithine metabolizing enzymes in testosterone-induced hypertrophic mouse kidney. Manteuffel-Cymborowska, M., Chmurzyńska, W., Peska, M., Grzelakowska-Sztabert, B. Int. J. Biochem. Cell Biol. (1995) [Pubmed]
  19. Development of ornithine metabolism in the mouse intestine. Riby, J.E., Hurwitz, R.E., Kretchmer, N. Pediatr. Res. (1990) [Pubmed]
  20. Decreased hyperammonaemia and orotic aciduria due to inactivation of ornithine aminotransferase in mice with a hereditary abnormal ornithine carbamoyltransferase. Seiler, N., Grauffel, C., Daune-Anglard, G., Sarhan, S., Knödgen, B. J. Inherit. Metab. Dis. (1994) [Pubmed]
  21. Localization and differential expression of arginase II in the kidney of male and female mice. Levillain, O., Balvay, S., Peyrol, S. Pflugers Arch. (2005) [Pubmed]
  22. Aberrations of ammonia metabolism in ornithine carbamoyltransferase-deficient spf-ash mice and their prevention by treatment with urea cycle intermediate amino acids and an ornithine aminotransferase inactivator. Li, M.X., Nakajima, T., Fukushige, T., Kobayashi, K., Seiler, N., Saheki, T. Biochim. Biophys. Acta (1999) [Pubmed]
  23. Increased renal 25-hydroxyvitamin D3-24-hydroxylase messenger ribonucleic acid and immunoreactive protein in phosphate-deprived Hyp mice: a mechanism for accelerated 1,25-dihydroxyvitamin D3 catabolism in X-linked hypophosphatemic rickets. Roy, S., Martel, J., Ma, S., Tenenhouse, H.S. Endocrinology (1994) [Pubmed]
  24. Interrelationships between ornithine, glutamate, and GABA. II. Consequences of inhibition of GABA-T and ornithine aminotransferase in brain. Daune, G., Seiler, N. Neurochem. Res. (1988) [Pubmed]
  25. Differential expression of the liver proteome in senescence accelerated mice. Cho, Y.M., Bae, S.H., Choi, B.K., Cho, S.Y., Song, C.W., Yoo, J.K., Paik, Y.K. Proteomics (2003) [Pubmed]
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