The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

AC1MHYNA     (2S,6S)-6-[[(2R)-2-[[(2S)-2- [[(2R)-2-[(2S...

Synonyms: 73715-37-4, Peptidoglycan monomer
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Peptidoglycan monomer


High impact information on Peptidoglycan monomer


Chemical compound and disease context of Peptidoglycan monomer


Biological context of Peptidoglycan monomer


Anatomical context of Peptidoglycan monomer


Associations of Peptidoglycan monomer with other chemical compounds


Gene context of Peptidoglycan monomer

  • Only insulin, concanavalin A (Con A), peptidoglycan monomer and a tumour-derived insulinoid stimulated [3H]thymidine incorporation by AOFS 21 cells and splenocytes [23].
  • The prepared compounds, namely anti-PGM antibodies and 125I-labelled Boc-L-tyrosyl-peptidoglycan monomer, were used as essential components in competitive radioimmunoassay for peptidoglycan monomer determination in mammalian and human sera and plasma, respectively [24].
  • Augmentation of NKT and NK cell-mediated cytotoxicity by peptidoglycan monomer linked with zinc [25].
  • 4. Serum and liver esterase activities were studied in mice treated with an immunostimulating agent, peptidoglycan monomer (PGM), and a comparison made with esterases from untreated mice [26].

Analytical, diagnostic and therapeutic context of Peptidoglycan monomer


  1. Enhancement of nonspecific immunity to Klebsiella pneumoniae infection by a synthetic immunoadjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine) and several analogs. Chedid, L., Parant, M., Parant, F., Lefrancher, P., Choay, J., Lederer, E. Proc. Natl. Acad. Sci. U.S.A. (1977) [Pubmed]
  2. Identification of novel inhibitors of Pseudomonas aeruginosa MurC enzyme derived from phage-displayed peptide libraries. El Zoeiby, A., Sanschagrin, F., Darveau, A., Brisson, J.R., Levesque, R.C. J. Antimicrob. Chemother. (2003) [Pubmed]
  3. Mutation of a single lytic transglycosylase causes aberrant septation and inhibits cell separation of Neisseria gonorrhoeae. Cloud, K.A., Dillard, J.P. J. Bacteriol. (2004) [Pubmed]
  4. Influence of adjuvant-active peptidoglycan monomer on specific T cell responses in mice. Halassy Spoljar, B., Cimbora, T., Hanzl-Dujmović, I., Dojnović, B., Sabioncello, A., Krstanović, M., Tomasić, J. Vaccine (2002) [Pubmed]
  5. Immunotherapy of Lewis lung carcinoma with hydrosoluble peptidoglycan monomer (PGM). Sava, G., Giraldi, T., Tomasić, J., Hrsak, I. Cancer Immunol. Immunother. (1983) [Pubmed]
  6. Effect of immunoadjuvant peptidoglycan monomer on liver cytochrome P-450. Tresćec, A., Iskrić, S., Hrsak, I., Tomasić, J. Biochem. Pharmacol. (1983) [Pubmed]
  7. Immunoprotective properties of peptidoglycan monomer linked with zinc in cholestatic jaundice. Ravlić-Gulan, J., Radosević-Stasić, B., Gulan, G., Stimac, D., Pavelić, K., Rukavina, D. Int. Arch. Allergy Immunol. (2000) [Pubmed]
  8. Comparative study of the effects of peptidoglycan monomer and structurally related adamantyltripeptides on humoral immune response to ovalbumin in the mouse. Tomasić, J., Hanzl-Dujmović, I., Spoljar, B., Vranesić, B., Santak, M., Jovicić, A. Vaccine (2000) [Pubmed]
  9. Immunoregulating effects of peptidoglycan monomer linked with zinc in adult mice. Radoŝević-Staŝić, B., Trobonjaĉa, Z., Petković, M., Milin, C., Cuk, M., Muhvić, D., Ravlić-Gulan, J., Marić, I., Rukavina, D. Int. Arch. Allergy Immunol. (1995) [Pubmed]
  10. Effects of postsurgical immunotherapy with PGM in mice bearing Lewis lung carcinoma treated with p-(3,3-dimethyl-1-triazeno) benzoic acid potassium salt. Sava, G., Zorzet, S., Perissin, L., Lassiani, L., Tomasic, J. Methods and findings in experimental and clinical pharmacology. (1985) [Pubmed]
  11. On the role of T lymphocytes in stimulation of humoral immunity induced by peptidoglycan-monomer linked with zinc. Ravlić-Gulan, J., Radosević-Stasić, B., Trobonjaca, Z., Petković, M., Cuk, M., Rukavina, D. Int. Arch. Allergy Immunol. (1999) [Pubmed]
  12. Comparative susceptibility of a peptidoglycan monomer from Brevibacterium divaricatum and its anhydromuramyl analogue to hydrolysis with N-acetylmuramyl-L-alanine amidase. Isolation and characterization of anhydromuramyl-peptidoglycan monomer. Tomasić, J., Sesartić, L., Martin, S.A., Valinger, Z., Ladesić, B. J. Chromatogr. (1988) [Pubmed]
  13. Pharmacokinetics of an immunomodulator peptidoglycan monomer in mice after intravenous administration. Ladesić, B., Perović, S., Hrsak, I. Int. J. Immunopharmacol. (1993) [Pubmed]
  14. Synthesis of novel adamantylacetyl derivative of peptidoglycan monomer--biological evaluation of immunomodulatory peptidoglycan monomer and respective derivatives with lipophilic substituents on amino group. Ljevaković, D., Tomasić, J., Sporec, V., Spoljar, B.H., Hanzl-Dujmovic, I. Bioorg. Med. Chem. (2000) [Pubmed]
  15. In vivo and in vitro modulation of NK and ADCC activities of mouse spleen cells by peptidoglycan monomer (PGM). Gabrilovac, J., Tomasić, J., Boranić, M., Martin-Kleiner, I., Osmak, M. Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. (1989) [Pubmed]
  16. Relationship of metabolism and immunostimulating activity of peptidoglycan monomer in mice after three different routes of administration. Valinger, Z., Ladesić, B., Hrsak, I., Tomasić, J. Int. J. Immunopharmacol. (1987) [Pubmed]
  17. In vivo modulating effects of bacterial peptidoglycans on PHA-induced responses of porcine PBL and splenocytes. Vijtiuk, N., Kosuta, D., Basić, I., Valpotić, I. Immunobiology (1993) [Pubmed]
  18. The involvement of CD14 in the activation of human monocytes by peptidoglycan monomers. Muhvić, D., El-Samalouti, V., Flad, H.D., Radosević-Stasić, B., Rukavina, D. Mediators of inflammation. (2001) [Pubmed]
  19. The metabolic fate of 14C-labeled immunoadjuvant peptidoglycan monomer. II. In vitro studies. Ladesić, B., Tomasić, J., Kveder, S., Hrsak, I. Biochim. Biophys. Acta (1981) [Pubmed]
  20. A peptidoglycan monomer as an antitumor agent in mice: stimulation of phagocytosis by resident peritoneal macrophages with peptidoglycan monomer. Rakocević, S., Silobrcić, V. Journal of biological response modifiers. (1988) [Pubmed]
  21. Activation of the human complement cascade by bacterial cell walls, peptidoglycans, water-soluble peptidoglycan components, and synthetic muramylpeptides--studies on active components and structural requirements. Kawasaki, A., Takada, H., Kotani, S., Inai, S., Nagaki, K., Matsumoto, M., Yokogawa, K., Kawata, S., Kusumoto, S., Shiba, T. Microbiol. Immunol. (1987) [Pubmed]
  22. Encapsulation of immunoadjuvant [14C]peptidoglycan monomer into liposomes. Effect on metabolism and immune response in mice. Tomasić, J., Hrsak, I. Biochim. Biophys. Acta (1982) [Pubmed]
  23. Insulin-modulated interleukin-2 production by murine splenocytes and a T-cell hybridoma. Pavelić, K., Bernacki, R.J., Vuk-Pavlović, S. J. Endocrinol. (1987) [Pubmed]
  24. A competitive radioimmunoassay for peptidoglycan monomer. Vranesić, B., Ljevaković, D., Tomasić, J., Ladesić, B. Clin. Chim. Acta (1991) [Pubmed]
  25. Augmentation of NKT and NK cell-mediated cytotoxicity by peptidoglycan monomer linked with zinc. Mrakovcić-Sutić, I., Radosević-Stasić, B., Simin, M., Muhvić, D., Rukavina, D. Mediators of inflammation. (2002) [Pubmed]
  26. Enzymatic deacylations of esterified saccharides. II. De-esterifications of radiolabelled O-acylglucopyranosides by mice serum and liver esterases. Tomić, S., Trescec, A., Tomasić, J. Comp. Biochem. Physiol., B (1987) [Pubmed]
  27. A novel ELISA for determination of polysaccharide specific immunoglobulins. Spoljar, B.H., Tomasic, J. Vaccine (2000) [Pubmed]
  28. N.m.r. titration of a natural immunoadjuvant, disaccharide-pentapeptide, peptidoglycan monomer and related compounds. Klaić, B., Ljubić, B., Metelko, B., Pongracić, M. Carbohydr. Res. (1983) [Pubmed]
WikiGenes - Universities