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Chemical Compound Review

TMAC     tetramethylazanium hydrochloride

Synonyms: AC1LC3BS
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Disease relevance of tetramethylammonium

  • Southern hybridization testing of the broad-range probes with washes containing 3 M tetramethylammonium chloride indicated that this set of probes correctly identified all but two of the 102 bacterial species tested, the exceptions being Deinococcus radiopugnans and Gardnerella vaginalis [1].

High impact information on tetramethylammonium


Biological context of tetramethylammonium


Anatomical context of tetramethylammonium

  • When culture medium NaC; is replaced with tetramethylammonium chloride, however, both normal and RSV-infected fibroblasts alike approach proliferative inactivity in the presence of 110 mM Na and both die off in the presence of 90 mM Na [7].

Associations of tetramethylammonium with other chemical compounds


Gene context of tetramethylammonium


Analytical, diagnostic and therapeutic context of tetramethylammonium


  1. PCR primers and probes for the 16S rRNA gene of most species of pathogenic bacteria, including bacteria found in cerebrospinal fluid. Greisen, K., Loeffelholz, M., Purohit, A., Leong, D. J. Clin. Microbiol. (1994) [Pubmed]
  2. Base composition-independent hybridization in tetramethylammonium chloride: a method for oligonucleotide screening of highly complex gene libraries. Wood, W.I., Gitschier, J., Lasky, L.A., Lawn, R.M. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  3. Reaction of the C30A mutant of trimethylamine dehydrogenase with diethylmethylamine. Huang, L., Scrutton, N.S., Hille, R. J. Biol. Chem. (1996) [Pubmed]
  4. Calcium transport in intact human erthrocytes. Plishker, G., Gitelman, H.J. J. Gen. Physiol. (1976) [Pubmed]
  5. Solvation of tetraalkylammonium chlorides in acetonitrile-water mixtures: mass spectrometry and molecular dynamics simulations. Saielli, G., Scorrano, G., Bagno, A., Wakisaka, A. Chemphyschem : a European journal of chemical physics and physical chemistry. (2005) [Pubmed]
  6. Cardiovascular effects of carbachol and other cholinomimetics administered into the cerebral ventricles of conscious cats. Day, M.D., Roach, A.G. Clin. Exp. Pharmacol. Physiol. (1977) [Pubmed]
  7. Effect of reduction of culture medium sodium, using different sodium chloride substitutes, on the proliferation of normal and Rous sarcoma virus-infected chicken fibroblasts. Balk, S.D., Polimeni, P.I. J. Cell. Physiol. (1982) [Pubmed]
  8. Continuous determination of extracellular space and changes of K+, Na+, Ca2+, and H+ during global ischaemia in isolated rat hearts. Knopf, H., Theising, R., Moon, C.H., Hirche, H. J. Mol. Cell. Cardiol. (1990) [Pubmed]
  9. High-performance liquid chromatographic determination of mitoxantrone in plasma utilizing non-bonded silica gel for solid-phase isolation to reduce adsorptive losses on glass during sample preparation. Lin, K.T., Rivard, G.E., Leclerc, J.M. J. Chromatogr. (1989) [Pubmed]
  10. Oxidation-reduction properties of trimethylamine dehydrogenase: effect of inhibitor binding. Pace, C.P., Stankovich, M.T. Arch. Biochem. Biophys. (1991) [Pubmed]
  11. Belladonna alkaloids and phenobarbital combination pharmaceuticals analysis II: High-performance liquid chromatographic determination of phenobarbital. Schmidt, W.F., Pennington, L.J. Journal of pharmaceutical sciences. (1982) [Pubmed]
  12. Isoelectric focusing subtypes of HLA-A can be defined by oligonucleotide typing. Oh, S.H., Fleischhauer, K., Yang, S.Y. Tissue Antigens (1993) [Pubmed]
  13. Structural organization of the human isovaleryl-CoA dehydrogenase gene. Parimoo, B., Tanaka, K. Genomics (1993) [Pubmed]
  14. Histone H1: ultracentrifugation studies of the effects of ionic strength and denaturants on the solution conformation. Lewis, E.A., Reams, R.R. Arch. Biochem. Biophys. (1983) [Pubmed]
  15. One-step molecular HLA-DR prescreening employing a set of 14 sequence specific oligonucleotides in a non-radioactive tetramethylammonium chloride hybridization protocol. Sorg, U.R., Enczmann, J., Sorg, R.V., Wernet, P. Eur. J. Immunogenet. (1992) [Pubmed]
  16. Low concentrations of tetramethylammonium chloride increase yield and specificity of PCR. Chevet, E., Lemaître, G., Katinka, M.D. Nucleic Acids Res. (1995) [Pubmed]
  17. Effect of tetramethylammonium ion on the helix-to-coil transition of poly(deoxyadenylylthymidine): a nuclear magnetic resonance and calorimetric investigation. Marky, L.A., Patel, D., Breslauer, K.J. Biochemistry (1981) [Pubmed]
  18. Voltage and ionic regulation of human serotonin transporter in Xenopus oocytes. Li, C., Zhong, H., Wang, Y., Wang, H., Yang, Z., Zheng, Y., Liu, K., Liu, Y. Clin. Exp. Pharmacol. Physiol. (2006) [Pubmed]
  19. Separation in a single step by affinity chromatography of cholinesterases differing in subunit number. Andres, C., el Mourabit, M., Mark, J., Waksman, A. Protein Expr. Purif. (1991) [Pubmed]
  20. Determination of pentamidine isethionate in air. Tucker, S.P., Belinky, B.R., Seitz, T.A., Foley, G.D. American Industrial Hygiene Association journal. (1993) [Pubmed]
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