Chemical Compound Review:
Ozex 7-(3-aminopyrrolidin-1-yl)-1- (2,4...
Synonyms:
TFLX, Tosufloxacin, Abbott-61827, SureCN34354, AGN-PC-00C1LC, ...
- In vitro activity of tosufloxacin, a new quinolone, against respiratory pathogens derived from cystic fibrosis sputum. Arguedas, A.G., Akaniro, J.C., Stutman, H.R., Marks, M.I. Antimicrob. Agents Chemother. (1990)
- Intracellular activity of tosufloxacin (T-3262) against Salmonella enteritidis and ability to penetrate into tissue culture cells of human origin. Noumi, T., Nishida, N., Minami, S., Watanabe, Y., Yasuda, T. Antimicrob. Agents Chemother. (1990)
- A-61827 (A-60969), a new fluoronaphthyridine with activity against both aerobic and anaerobic bacteria. Fernandes, P.B., Chu, D.T., Swanson, R.N., Ramer, N.R., Hanson, C.W., Bower, R.R., Stamm, J.M., Hardy, D.J. Antimicrob. Agents Chemother. (1988)
- In vitro and in vivo antibacterial activities of CS-940, a new fluoroquinolone, against isolates from patients with respiratory infections. Miyazaki, S., Domon, H., Tateda, K., Ohno, A., Ishii, Y., Matsumoto, T., Furuya, N., Yamaguchi, K. Antimicrob. Agents Chemother. (1997)
- Antibacterial activities and pharmacokinetics of E-4767 and E-5065, two new 8-chlorofluoroquinolones with a 7-azetidin ring substituent. Gargallo-Viola, D., Ferrer, S., Tudela, E., Robert, M., Coll, R., Roser, R., Guinea, J. Antimicrob. Agents Chemother. (2001)
- In vitro and in vivo activities of sitafloxacin against Chlamydia spp. Miyashita, N., Niki, Y., Matsushima, T. Antimicrob. Agents Chemother. (2001)
- Salmonella excretion after cessation of tosufloxacin therapy in acute nontyphoid salmonella enterocolitis. Ohnishi, K., Kimura, K. Antimicrob. Agents Chemother. (2001)
- Effects of aluminum hydroxide and famotidine on bioavailability of tosufloxacin in healthy volunteers. Minami, R., Nakamura, C., Inotsume, N., Nakano, M. Antimicrob. Agents Chemother. (1998)
- In vitro and in vivo antichlamydial activities of newly developed quinolone antimicrobial agents. Kimura, M., Kishimoto, T., Niki, Y., Soejima, R. Antimicrob. Agents Chemother. (1993)
- Comparative in-vitro and in-vivo activity of AM-1155 against anaerobic bacteria. Kato, N., Kato, H., Tanaka-Bandoh, K., Watanabe, K., Ueno, K. J. Antimicrob. Chemother. (1997)
- In vitro activity of pazufloxacin, tosufloxacin and other quinolones against Legionella species. Higa, F., Akamine, M., Haranaga, S., Tohyama, M., Shinzato, T., Tateyama, M., Koide, M., Saito, A., Fujita, J. J. Antimicrob. Chemother. (2005)
- In-vitro activity of tosufloxacin, a new quinolone antibacterial agent. Cooper, M.A., Andrews, J.M., Wise, R. J. Antimicrob. Chemother. (1992)
- Alteration of constitutive apoptosis in neutrophils by quinolones. Azuma, Y., Ohura, K. Inflammation (2003)
- Stereoselective analysis of the disposition of tosufloxacin enantiomers in man. Minami, R., Inotsume, N., Nakamura, C., Nakano, M. Eur. J. Clin. Pharmacol. (1993)
- Antibacterial activities of tosufloxacin against anaerobic bacteria and the electron micrograph of its bactericidal effects. Takahata, M., Nishino, T. Chemotherapy. (1997)
- Therapeutic effect of the quinolone prodrug prulifloxacin against experimental urinary tract infections in mice. Tomii, Y., Ozaki, M., Matsuda, M., Honmura, T., Nishimura, I., Yamaguchi, R., Adachi, T., Okawa, Y., Nishino, T. Arzneimittel-Forschung. (1996)
- Quinolones alter defense reactions mediated by macrophages. Azuma, Y., Shinohara, M., Wang, P.L., Ohura, K. Int. Immunopharmacol. (2001)
- In vitro and in vivo antibacterial activities of a new quinolone, OPC-17116. Imada, T., Miyazaki, S., Nishida, M., Yamaguchi, K., Goto, S. Antimicrob. Agents Chemother. (1992)
- In vitro activity of tosufloxacin (A-61827; T-3262) against selected genital pathogens. Segreti, J., Hirsch, D.J., Harris, A.A., Kapell, K.S., Orbach, H., Kessler, H.A. Antimicrob. Agents Chemother. (1990)
- In-vitro activities of temafloxacin, tosufloxacin (A-61827) and five other fluoroquinolone agents. Barry, A.L., Jones, R.N. J. Antimicrob. Chemother. (1989)
- Pharmacodynamic evaluation of tosufloxacin against Streptococcus pneumoniae in an in vitro model simulating serum concentration. Fukuda, Y., Takahata, M., Mitsuyama, J. J. Infect. Chemother. (2006)
- Susceptibilities of 394 Bacteroides fragilis, non-B. fragilis group Bacteroides species, and Fusobacterium species to newer antimicrobial agents. Appelbaum, P.C., Spangler, S.K., Jacobs, M.R. Antimicrob. Agents Chemother. (1991)
- Dual inhibitory activity of sitafloxacin (DU-6859a) against DNA gyrase and topoisomerase IV of Streptococcus pneumoniae. Onodera, Y., Uchida, Y., Tanaka, M., Sato, K. J. Antimicrob. Chemother. (1999)
- Pulmonary infiltration with eosinophilia (PIE) syndrome induced by antibiotics, PIPC and TFLX during cancer treatment. Yamamoto, T., Tanida, T., Ueta, E., Kimura, T., Doi, S., Osaki, T. Oral Oncol. (2001)
- Susceptibility of anaerobic bacteria to tosufloxacin. Nord, C.E., Lindmark, A., Persson, I., Runow, C. Eur. J. Clin. Microbiol. Infect. Dis. (1992)
- Sensitivity of Staphylococcus aureus, isolated from skin infections in 1994, to 19 antimicrobial agents. Nishijima, S., Nakagawa, M., Sugiyama, T., Akamatsu, H., Horio, T., Kawabata, S., Fujita, M. J. Int. Med. Res. (1995)