Chemical Compound Review:
PHENOTAZINE 10H-phenoxazine
Synonyms:
Phenazoxine, Phenoxazine, SureCN7862, CHEMBL276850, P14858_ALDRICH, ...
- Photosensitization, uptake, and retention of phenoxazine Nile blue derivatives in human bladder carcinoma cells. Lin, C.W., Shulok, J.R., Wong, Y.K., Schanbacher, C.F., Cincotta, L., Foley, J.W. Cancer Res. (1991)
- Chlamydia pneumoniae growth inhibition in human monocytic THP-1 cells and human epithelial HEp-2 cells by a novel phenoxazine derivative. Uruma, T., Yamaguchi, H., Fukuda, M., Kawakami, H., Goto, H., Kishimoto, T., Yamamoto, Y., Tomoda, A., Kamiya, S. J. Med. Microbiol. (2005)
- Caspase-independent cell death revealed in human gastric cancer cell lines, MKN45 and KATO III treated with phenoxazine derivatives. Kasuga, T., Tabuchi, T., Shirato, K., Imaizumi, K., Tomoda, A. Oncol. Rep. (2007)
- Isolation and structure of a new phenoxazine antibiotic, exfoliazone, produced by Streptomyces exfoliatus. Imai, S., Shimazu, A., Furihata, K., Furihata, K., Hayakawa, Y., Seto, H. J. Antibiot. (1990)
- Cellular penetration and antisense activity by a phenoxazine-substituted heptanucleotide. Flanagan, W.M., Wagner, R.W., Grant, D., Lin, K.Y., Matteucci, M.D. Nat. Biotechnol. (1999)
- Rational design of potent human transthyretin amyloid disease inhibitors. Klabunde, T., Petrassi, H.M., Oza, V.B., Raman, P., Kelly, J.W., Sacchettini, J.C. Nat. Struct. Biol. (2000)
- Antitumor effects of a novel phenoxazine derivative on human leukemia cell lines in vitro and in vivo. Shimamoto, T., Tomoda, A., Ishida, R., Ohyashiki, K. Clin. Cancer Res. (2001)
- Pharmacological characterization of N-substituted phenoxazines directed toward reversing Vinca alkaloid resistance in multidrug-resistant cancer cells. Horton, J.K., Thimmaiah, K.N., Harwood, F.C., Kuttesch, J.F., Houghton, P.J. Mol. Pharmacol. (1993)
- Synthesis of thiol-reactive, long-wavelength fluorescent phenoxazine derivatives for biosensor applications. Sherman, D.B., Pitner, J.B., Ambroise, A., Thomas, K.J. Bioconjug. Chem. (2006)
- Antitumor activity of 2-amino-4,4 alpha-dihydro-4 alpha, 7-dimethyl-3H-phenoxazine-3-one, a novel phenoxazine derivative produced by the reaction of 2-amino-5-methylphenol with bovine hemolysate. Ishida, R., Yamanaka, S., Kawai, H., Ito, H., Iwai, M., Nishizawa, M., Hamatake, M., Tomoda, A. Anticancer Drugs (1996)
- Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes. Tang, Y.Z., Liu, Z.Q. Bioorg. Med. Chem. (2007)
- Cancer chemopreventive effect of phenothiazines and related tri-heterocyclic analogues in the 12-O-tetradecanoylphorbol-13-acetate promoted Epstein-Barr virus early antigen activation and the mouse skin two-stage carcinogenesis models. Azuine, M.A., Tokuda, H., Takayasu, J., Enjyo, F., Mukainaka, T., Konoshima, T., Nishino, H., Kapadia, G.J. Pharmacol. Res. (2004)
- Kinetics of cellular permeability of phenoxazine and its dependence on P-glycoprotein expression. Wadkins, R.M., Houghton, P.J. FEBS Lett. (1993)
- Antitumor activity of a phenoxazine compound, 2-amino-4,4alpha-dihydro-4alpha,7-dimethyl-3H-phenoxazine-3-one against human B cell and T cell lymphoblastoid cell lines: induction of mixed types of cell death, apoptosis, and necrosis. Koshibu-Koizumi, J., Akazawa, M., Iwamoto, T., Takasaki, M., Mizuno, F., Kobayashi, R., Abe, A., Tomoda, A., Hamatake, M., Ishida, R. J. Cancer Res. Clin. Oncol. (2002)
- Inhibition of calmodulin-dependent cyclic AMP phosphodiesterase by phenoxazines. Jagadeesh, S., Padma, T., Parimala, H., Chandramouli, K.H., D'Souza, C.J., Thimmaiah, K.N. Biochem. Biophys. Res. Commun. (2006)
- A novel phenoxazine derivative suppresses proliferation of human endometrial adenocarcinoma cell lines, inducing G2M accumulation and apoptosis. Nakada, T., Isaka, K., Nishi, H., Osakabe, Y., Shimamoto, T., Ohyashiki, K., Tomoda, A., Takayama, M. Oncol. Rep. (2003)
- The percutaneous absorption of triarylmethane and phenoxazine type colour former components of carbonless copy papers. Cameron, B.D., Dunsire, J.P., Draffan, G.H., Bruce, J.C. The Annals of occupational hygiene. (1986)
- A novel phenoxazine derivative suppresses surface IgM expression in DT40 B cell line. Gao, S., Takano, T., Sada, K., He, J., Noda, C., Hori-Tamura, N., Tomoda, A., Yamamura, H. Br. J. Pharmacol. (2002)
- The phenoxazine derivative Phx-1 suppresses IgE-mediated degranulation in rat basophilic leukemia RBL-2H3 cells. Enoki, E., Sada, K., Qu, X., Kyo, S., Miah, S.M., Hatani, T., Tomoda, A., Yamamura, H. J. Pharmacol. Sci. (2004)
- A phenoxazine compound, 2-amino-4,4alpha-dihydro-4alpha-7-dimethyl-3H-phenoxazine-3-one reverses the phenylephrine or high-K+ induced contraction of smooth muscles in rat aorta and guinea pig tenia cecum. Musha, S., Watanabe, M., Ishida, Y., Kato, S., Konishi, M., Tomoda, A. Biol. Pharm. Bull. (2005)
- Structural determinants of phenoxazine type compounds required to modulate the accumulation of vinblastine and vincristine in multidrug-resistant cell lines. Thimmaiah, K.N., Horton, J.K., Qian, X.D., Beck, W.T., Houghton, J.A., Houghton, P.J. Cancer Commun. (1990)
- A long-wavelength fluorescent glucose biosensor based on bioconjugates of galactose/glucose binding protein and Nile Red derivatives. Thomas, K.J., Sherman, D.B., Amiss, T.J., Andaluz, S.A., Pitner, J.B. Diabetes Technol. Ther. (2006)
- Synthesis and ESR studies of redox reactivity of bis (3,5-di-tert-butyl-1,2-benzoquinone-2-monooximato)Cu(II). Kasumov, V.T., Kartal, I., Koksal, F. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. (2000)
- Synergistic enhancement of TRAIL- and tumor necrosis factor alpha-induced cell death by a phenoxazine derivative. Hara, K., Okamoto, M., Aki, T., Yagita, H., Tanaka, H., Mizukami, Y., Nakamura, H., Tomoda, A., Hamasaki, N., Kang, D. Mol. Cancer Ther. (2005)