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Chemical Compound Review

Altitran     1-chloro-2-nitro-benzene

Synonyms: ONCB, PubChem18481, CCRIS 141, CHEMBL53330, SureCN78743, ...
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Disease relevance of Chloro-o-nitrobenzene


High impact information on Chloro-o-nitrobenzene


Chemical compound and disease context of Chloro-o-nitrobenzene


Biological context of Chloro-o-nitrobenzene


Anatomical context of Chloro-o-nitrobenzene


Associations of Chloro-o-nitrobenzene with other chemical compounds


Gene context of Chloro-o-nitrobenzene

  • Determination of strain CNB-1 populations by cultivation method and by quantitative competitive PCR technique targeting the chloronitrobenzene nitroreductase gene showed that the population of strain CNB-1 in the rhizosphere was about 10-100 times higher than that in the bulk soil [16].

Analytical, diagnostic and therapeutic context of Chloro-o-nitrobenzene


  1. Degradation of chloronitrobenzenes by a coculture of Pseudomonas putida and a Rhodococcus sp. Park, H.S., Lim, S.J., Chang, Y.K., Livingston, A.G., Kim, H.S. Appl. Environ. Microbiol. (1999) [Pubmed]
  2. A Novel Deaminase Involved in Chloronitrobenzene and Nitrobenzene Degradation with Comamonas sp. Strain CNB-1. Liu, L., Wu, J.F., Ma, Y.F., Wang, S.Y., Zhao, G.P., Liu, S.J. J. Bacteriol. (2007) [Pubmed]
  3. In vitro nephrotoxicity induced by chloronitrobenzenes in renal cortical slices from Fischer 344 rats. Hong, S.K., Anestis, D.K., Ball, J.G., Valentovic, M.A., Rankin, G.O. Toxicol. Lett. (2002) [Pubmed]
  4. Mechanism for the several activities of the glutathione S-transferases. Keen, J.H., Habig, W.H., Jakoby, W.B. J. Biol. Chem. (1976) [Pubmed]
  5. Mechanism-based phage display selection of active-site mutants of human glutathione transferase A1-1 catalyzing SNAr reactions. Hansson, L.O., Widersten, M., Mannervik, B. Biochemistry (1997) [Pubmed]
  6. Ag/SiO2: a novel catalyst with high activity and selectivity for hydrogenation of chloronitrobenzenes. Chen, Y., Wang, C., Liu, H., Qiu, J., Bao, X. Chem. Commun. (Camb.) (2005) [Pubmed]
  7. Metabolism of chloronitrobenzenes by isolated rat hepatocytes. Rickert, D.E., Held, S.D. Drug Metab. Dispos. (1990) [Pubmed]
  8. Characterization of genes involved in the initial reactions of 4-chloronitrobenzene degradation in Pseudomonas putida ZWL73. Xiao, Y., Wu, J.F., Liu, H., Wang, S.J., Liu, S.J., Zhou, N.Y. Appl. Microbiol. Biotechnol. (2006) [Pubmed]
  9. DNA damage induced in vivo in various tissues by nitrochlorobenzene derivatives. Cesarone, C.F., Bolognesi, C., Santi, L. Mutat. Res. (1983) [Pubmed]
  10. Influence of the culture time on DNA damage and repair in isolated rat hepatocytes exposed to nitrochlorobenzene derivatives. Cesarone, C.F., Fugassa, E., Gallo, G., Voci, A., Orunesu, M. Mutat. Res. (1984) [Pubmed]
  11. Structural specificity of aromatic compounds with special reference to mutagenic activity in Salmonella typhimurium--a series of chloro- or fluoro-nitrobenzene derivatives. Shimizu, M., Yasui, Y., Matsumoto, N. Mutat. Res. (1983) [Pubmed]
  12. Structure relationship of nitrochlorobenzene catalytic degradation process in water over palladium-iron bimetallic catalyst. Niu, S.F., Zhou, H.Y., Ao, X.P., Xu, X.H., Lou, Z.H. Journal of Zhejiang University. Science. B. (2006) [Pubmed]
  13. Assessment of toxicity of o-nitrochlorobenzene in rats following a 4-week inhalation exposure. Nair, R.S., Johannsen, F.R., Levinskas, G.J., Terrill, J.B. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1986) [Pubmed]
  14. Heterogeneity of CD80 gene transcription by human keratinocytes to allergens and irritants: relevance to allergic contact dermatitis in vivo. Wakem, P., Ramirez, F., Zlotnick, D., Gaspari, A.A. Journal of applied toxicology : JAT. (2004) [Pubmed]
  15. The acute mammalian toxicology of dibenz(b,f)-1,4-oxazepine. Ballantyne, B. Toxicology (1977) [Pubmed]
  16. Plant-microbe association for rhizoremediation of chloronitroaromatic pollutants with Comamonas sp. strain CNB-1. Liu, L., Jiang, C.Y., Liu, X.Y., Wu, J.F., Han, J.G., Liu, S.J. Environ. Microbiol. (2007) [Pubmed]
  17. Full stereochemical assignment and synthesis of the potent anthelmintic pyrrolobenzoxazine natural product CJ-12662. Didier, C., Critcher, D.J., Walshe, N.D., Kojima, Y., Yamauchi, Y., Barrett, A.G. J. Org. Chem. (2004) [Pubmed]
  18. Submolecular imaging of chloronitrobenzene isomers on Cu(111). Niemi, E., Simic-Milosevic, V., Morgenstern, K., Korventausta, A., Paavilainen, S., Nieminen, J. The Journal of chemical physics (2006) [Pubmed]
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