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Chemical Compound Review

SureCN12727823     3-[3,4-dihydroxy-5- (phosphonooxymethyl)oxo...

Synonyms: AC1L1AFN, AC1Q6RZF, AR-1D5085, 2149-82-8, OMP
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Disease relevance of Orotidylic acid


High impact information on Orotidylic acid


Biological context of Orotidylic acid


Anatomical context of Orotidylic acid


Associations of Orotidylic acid with other chemical compounds


Gene context of Orotidylic acid


Analytical, diagnostic and therapeutic context of Orotidylic acid


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  4. Nucleotide sequence of the Penicillium chrysogenum pyrG (orotidine-5'-phosphate decarboxylase) gene. Cantoral, J.M., Barredo, J.L., Alvarez, E., Díez, B., Martín, J.F. Nucleic Acids Res. (1988) [Pubmed]
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  8. Cloning, mapping and molecular analysis of the pyrG (orotidine-5'-phosphate decarboxylase) gene of Aspergillus nidulans. Oakley, B.R., Rinehart, J.E., Mitchell, B.L., Oakley, C.E., Carmona, C., Gray, G.L., May, G.S. Gene (1987) [Pubmed]
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  11. A DNA sequence from Dictyostelium discoideum complements ura3 and ura5 mutations of Saccharomyces cerevisiae. Boy-Marcotte, E., Vilaine, F., Camonis, J., Jacquet, M. Mol. Gen. Genet. (1984) [Pubmed]
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  14. Inhibition of orotidine-5'-phosphate decarboxylase by 1-(5'-phospho-beta-d-ribofuranosyl)barbituric acid, 6-azauridine 5'-phosphate, and uridine 5'-phosphate. Levine, H.L., Brody, R.S., Westheimer, F.H. Biochemistry (1980) [Pubmed]
  15. Transformation system for a wastewater treatment yeast, Hansenula fabianii J640: isolation of the orotidine-5'-phosphate decarboxylase gene (URA3) and uracil auxotrophic mutants. Kato, M., Iefuji, H., Miyake, K., Iimura, Y. Appl. Microbiol. Biotechnol. (1997) [Pubmed]
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  17. Cloning of the C-URA3 gene and construction of a triple auxotroph (his5, ade1, ura3) as a useful host for the genetic engineering of Candida maltosa. Ohkuma, M., Muraoka, S., Hwang, C.W., Ohta, A., Takagi, M. Curr. Genet. (1993) [Pubmed]
  18. An alternative explanation for the catalytic proficiency of orotidine 5'-phosphate decarboxylase. Lee, T.S., Chong, L.T., Chodera, J.D., Kollman, P.A. J. Am. Chem. Soc. (2001) [Pubmed]
  19. Structural evidence for a 1,2-enediolate intermediate in the reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase, a member of the orotidine 5'-monophosphate decarboxylase suprafamily. Wise, E.L., Yew, W.S., Gerlt, J.A., Rayment, I. Biochemistry (2003) [Pubmed]
  20. In vitro inhibition of Plasmodium falciparum by pyrazofurin, an inhibitor of pyrimidine biosynthesis de novo. Scott, H.V., Gero, A.M., O'Sullivan, W.J. Mol. Biochem. Parasitol. (1986) [Pubmed]
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