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Gene Review

Cpl1  -  plasma corticosterone level 1

Mus musculus

Synonyms: Cpl-1
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Disease relevance of Cpl1

  • Phage lytic enzyme Cpl-1 as a novel antimicrobial for pneumococcal bacteremia [1].
  • The in vivo effects of a dose-ranging treatment, using either of the phage-coded lytic enzymes Cpl-1 lysozyme or the Pal amidase, have been investigated here in a murine sepsis model [2].
  • Plasma corticosterone level was markedly increased at 3 h after pertussis toxin injection (0.03 and 0.2 microg/mouse), peaked at 6 h and was still increased for up to 6 days after injection [3].

High impact information on Cpl1


Biological context of Cpl1


Anatomical context of Cpl1


Associations of Cpl1 with chemical compounds


Other interactions of Cpl1


Analytical, diagnostic and therapeutic context of Cpl1


  1. Phage lytic enzyme Cpl-1 as a novel antimicrobial for pneumococcal bacteremia. Loeffler, J.M., Djurkovic, S., Fischetti, V.A. Infect. Immun. (2003) [Pubmed]
  2. Phage lytic enzymes as therapy for antibiotic-resistant Streptococcus pneumoniae infection in a murine sepsis model. Jado, I., López, R., García, E., Fenoll, A., Casal, J., García, P. J. Antimicrob. Chemother. (2003) [Pubmed]
  3. Increased plasma corticosterone, aggressiveness and brain monoamine changes induced by central injection of pertussis toxin. Kim, D.H., Jung, J.S., Yan, J.J., Suh, H.W., Son, B.K., Kim, Y.H., Song, D.K. Eur. J. Pharmacol. (2000) [Pubmed]
  4. Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3. Hansen, C.S., Marion, C.D., Steele, K., George, S., Smith, W.C. Development (1997) [Pubmed]
  5. Expressional regulation of the angiopoietin-1 and -2 and the endothelial-specific receptor tyrosine kinase Tie2 in adrenal atrophy: a study of adrenocorticotropin-induced repair. Féraud, O., Mallet, C., Vilgrain, I. Endocrinology (2003) [Pubmed]
  6. A study of the role of corticosterone as a mediator in exercise-induced stimulation of murine macrophage phagocytosis. Forner, M.A., Barriga, C., Rodriguez, A.B., Ortega, E. J. Physiol. (Lond.) (1995) [Pubmed]
  7. Behavioral effects of urotensin-II centrally administered in mice. Do-Rego, J.C., Chatenet, D., Orta, M.H., Naudin, B., Le Cudennec, C., Leprince, J., Scalbert, E., Vaudry, H., Costentin, J. Psychopharmacology (Berl.) (2005) [Pubmed]
  8. Modulation of 5-HT system in mice with a targeted disruption of neuromedin B receptor. Yamano, M., Ogura, H., Okuyama, S., Ohki-Hamazaki, H. J. Neurosci. Res. (2002) [Pubmed]
  9. Panax ginseng blocks morphine-induced thymic apoptosis by lowering plasma corticosterone level. Kim, Y.R., Lee, S.Y., Shin, B.A., Kim, K.M. Gen. Pharmacol. (1999) [Pubmed]
  10. Expression of major histocompatibility complex in mouse peritoneal macrophages increasingly depends on plasma corticosterone levels: stimulation by aconitine. Kimura, I., Makino, M., Honda, R., Ma, J., Kimura, M. Biol. Pharm. Bull. (1995) [Pubmed]
  11. Enhanced 5-HT1A receptor expression in forebrain regions of aggressive house mice. Korte, S.M., Meijer, O.C., de Kloet, E.R., Buwalda, B., Keijser, J., Sluyter, F., van Oortmerssen, G., Bohus, B. Brain Res. (1996) [Pubmed]
  12. Mechanism of the central hyperglycemic action of histamine in mice. Nishibori, M., Itoh, Y., Oishi, R., Saeki, K. J. Pharmacol. Exp. Ther. (1987) [Pubmed]
  13. Inhibition of brain protein kinase C attenuates immobilization stress-induced plasma corticosterone levels in mice. Kim, D.H., Jung, J.S., Kim, H.S., Suh, H.W., Son, B.K., Kim, Y.H., Song, D.K. Neurosci. Lett. (2000) [Pubmed]
  14. Modafinil-induced modulation of working memory and plasma corticosterone in chronically-stressed mice. Piérard, C., Liscia, P., Valleau, M., Drouet, I., Chauveau, F., Huart, B., Bonneau, D., Jouanin, J.C., Beaumont, M., Béracochéa, D. Pharmacol. Biochem. Behav. (2006) [Pubmed]
  15. Serotonin depletion enhances the intracerebroventricularly administered MK-801-induced plasma interleukin-6 levels in mice. Kim, D.H., Jung, J.S., Moon, Y.S., Suh, H.W., Song, D.K. Biol. Pharm. Bull. (2003) [Pubmed]
  16. Inhibition of intracerebroventricular injection stress-induced plasma corticosterone levels by intracerebroventricularly administered compound K, a ginseng saponin metabolite, in mice. Kim, D.H., Jung, J.S., Moon, Y.S., Sung, J.H., Suh, H.W., Kim, Y.H., Song, D.K. Biol. Pharm. Bull. (2003) [Pubmed]
  17. Social structure and plasma corticosterone level in female albino mice. Schuhr, B. Physiol. Behav. (1987) [Pubmed]
  18. Effect of dexamethasone and endogenous corticosterone on airway hyperresponsiveness and eosinophilia in the mouse. De Bie, J.J., Hessel, E.M., Van Ark, I., Van Esch, B., Hofman, G., Nijkamp, F.P., Van Oosterhout, A.J. Br. J. Pharmacol. (1996) [Pubmed]
  19. Plasma and adrenal corticosterone concentrations and liver glycogen content in premature mice at birth and during neonatal development. Loctin, J., Delost, P. Steroids (1983) [Pubmed]
  20. The algogenic-induced nociceptive flexion test in mice: studies on sensitivity of the test and stress on animals. Inoue, M., Rashid, M.H., Kawashima, T., Matsumoto, M., Maeda, T., Kishioka, S., Ueda, H. Brain Res. Bull. (2003) [Pubmed]
  21. Immunotoxicological insignificance of fenitrothion in mice and rats. Kunimatsu, T., Kamita, Y., Isobe, N., Kawasaki, H. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1996) [Pubmed]
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