Gene Review:
Kpna2 - karyopherin (importin) alpha 2
Mus musculus
Synonyms:
2410044B12Rik, IPOA1, Importin alpha, Importin alpha P1, Importin subunit alpha-1, ...
- Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha. Fontes, M.R., Teh, T., Jans, D., Brinkworth, R.I., Kobe, B. J. Biol. Chem. (2003)
- Cellular actions of the insulin-like growth factor binding proteins. Firth, S.M., Baxter, R.C. Endocr. Rev. (2002)
- Localization, interaction, and RNA binding properties of the V(D)J recombination-activating proteins RAG1 and RAG2. Spanopoulou, E., Cortes, P., Shih, C., Huang, C.M., Silver, D.P., Svec, P., Baltimore, D. Immunity (1995)
- Triggering neural differentiation of ES cells by subtype switching of importin-alpha. Yasuhara, N., Shibazaki, N., Tanaka, S., Nagai, M., Kamikawa, Y., Oe, S., Asally, M., Kamachi, Y., Kondoh, H., Yoneda, Y. Nat. Cell Biol. (2007)
- Synapse to nucleus signaling during long-term synaptic plasticity; a role for the classical active nuclear import pathway. Thompson, K.R., Otis, K.O., Chen, D.Y., Zhao, Y., O'Dell, T.J., Martin, K.C. Neuron (2004)
- Axoplasmic importins enable retrograde injury signaling in lesioned nerve. Hanz, S., Perlson, E., Willis, D., Zheng, J.Q., Massarwa, R., Huerta, J.J., Koltzenburg, M., Kohler, M., van-Minnen, J., Twiss, J.L., Fainzilber, M. Neuron (2003)
- Importin alpha/beta mediates nuclear transport of a mammalian circadian clock component, mCRY2, together with mPER2, through a bipartite nuclear localization signal. Sakakida, Y., Miyamoto, Y., Nagoshi, E., Akashi, M., Nakamura, T.J., Mamine, T., Kasahara, M., Minami, Y., Yoneda, Y., Takumi, T. J. Biol. Chem. (2005)
- A centriole- and RanGTP-independent spindle assembly pathway in meiosis I of vertebrate oocytes. Dumont, J., Petri, S., Pellegrin, F., Terret, M.E., Bohnsack, M.T., Rassinier, P., Georget, V., Kalab, P., Gruss, O.J., Verlhac, M.H. J. Cell Biol. (2007)
- Biophysical characterization of interactions involving importin-alpha during nuclear import. Catimel, B., Teh, T., Fontes, M.R., Jennings, I.G., Jans, D.A., Howlett, G.J., Nice, E.C., Kobe, B. J. Biol. Chem. (2001)
- Genomic organization and chromosomal localization of the importin alpha1 gene in the mouse. Miyamoto, Y., Kim, J., Yuba, S., Yoneda, Y. Gene (2002)
- Altered distributions of nucleocytoplasmic transport-related proteins in the spinal cord of a mouse model of amyotrophic lateral sclerosis. Zhang, J., Ito, H., Wate, R., Ohnishi, S., Nakano, S., Kusaka, H. Acta Neuropathol. (2006)
- In vivo evidence for involvement of a 58 kDa component of nuclear pore-targeting complex in nuclear protein import. Imamoto, N., Shimamoto, T., Takao, T., Tachibana, T., Kose, S., Matsubae, M., Sekimoto, T., Shimonishi, Y., Yoneda, Y. EMBO J. (1995)
- Yeast Srp1, a nuclear protein related to Drosophila and mouse pendulin, is required for normal migration, division, and integrity of nuclei during mitosis. Küssel, P., Frasch, M. Mol. Gen. Genet. (1995)
- Functional characterization of a plant importin alpha homologue. Nuclear localization signal (NLS)-selective binding and mediation of nuclear import of nls proteins in vitro. Jiang, C.J., Imamoto, N., Matsuki, R., Yoneda, Y., Yamamoto, N. J. Biol. Chem. (1998)
- Nuclear import of the retinoid X receptor, the vitamin D receptor, and their mutual heterodimer. Yasmin, R., Williams, R.M., Xu, M., Noy, N. J. Biol. Chem. (2005)
- Myb-binding protein 1a is a nucleocytoplasmic shuttling protein that utilizes CRM1-dependent and independent nuclear export pathways. Keough, R.A., Macmillan, E.M., Lutwyche, J.K., Gardner, J.M., Tavner, F.J., Jans, D.A., Henderson, B.R., Gonda, T.J. Exp. Cell Res. (2003)
- Crystallization of importin alpha, the nuclear-import receptor. Teh, T., Tiganis, T., Kobe, B. Acta Crystallogr. D Biol. Crystallogr. (1999)
- Role of prodomain in importin-mediated nuclear localization and activation of caspase-2. Baliga, B.C., Colussi, P.A., Read, S.H., Dias, M.M., Jans, D.A., Kumar, S. J. Biol. Chem. (2003)
- Importin alpha transports CaMKIV to the nucleus without utilizing importin beta. Kotera, I., Sekimoto, T., Miyamoto, Y., Saiwaki, T., Nagoshi, E., Sakagami, H., Kondo, H., Yoneda, Y. EMBO J. (2005)
- Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3. Faul, C., Hüttelmaier, S., Oh, J., Hachet, V., Singer, R.H., Mundel, P. J. Cell Biol. (2005)
- The nuclear pore-targeting complex binds to nuclear pores after association with a karyophile. Imamoto, N., Shimamoto, T., Kose, S., Takao, T., Tachibana, T., Matsubae, M., Sekimoto, T., Shimonishi, Y., Yoneda, Y. FEBS Lett. (1995)
- Nup50/Npap60 function in nuclear protein import complex disassembly and importin recycling. Matsuura, Y., Stewart, M. EMBO J. (2005)
- Impaired expression of importin/karyopherin beta1 leads to post-implantation lethality. Miura, K., Yoshinobu, K., Imaizumi, T., Haruna, K., Miyamoto, Y., Yoneda, Y., Nakagata, N., Araki, M., Miyakawa, T., Yamamura, K., Araki, K. Biochem. Biophys. Res. Commun. (2006)
- Cleavage stage porcine embryos may have differing developmental requirements for karyopherins alpha2 and alpha3. Cabot, R.A., Prather, R.S. Mol. Reprod. Dev. (2003)
- Differential importin-alpha recognition and nuclear transport by nuclear localization signals within the high-mobility-group DNA binding domains of lymphoid enhancer factor 1 and T-cell factor 1. Prieve, M.G., Guttridge, K.L., Munguia, J., Waterman, M.L. Mol. Cell. Biol. (1998)
- Association of the T-cell protein tyrosine phosphatase with nuclear import factor p97. Tiganis, T., Flint, A.J., Adam, S.A., Tonks, N.K. J. Biol. Chem. (1997)