High impact information on SPAG17

• The Chlamydomonas PF6 locus encodes a large alanine/proline-rich polypeptide that is required for assembly of a central pair projection and regulates flagellar motility [1].
• Sequence analysis indicates that the PF6 gene encodes a large polypeptide that contains numerous alanine-rich, proline-rich, and basic domains and has limited homology to an expressed sequence tag derived from a human testis cDNA library [1].
• In this article we explore in atomistic detail and explain in an intuitive way the peculiar volumetric behavior experimentally observed when supercritical CO2 is dissolved in 1-butyl-3-methylimidazolium hexafluorophosphate ([Bmim+] [PF6(-)]) [2].
• Why is the partial molar volume of CO2 so small when dissolved in a room temperature ionic liquid? Structure and dynamics of CO2 dissolved in [Bmim+] [PF6(-)] [2].
• TpRu(PPh3)(CH3CN)2 PF6 (10 mol %) catalyst effected the nucleophilic addition of water, alcohols, aniline, acetylacetone, pyrroles, and dimethyl malonate to unfunctionalized enediynes under suitable conditions (100 degrees C, 12-24 h) and gave functionalized benzene products in good yields [3].

Biological context of SPAG17

• We report structure-activity relationships for organometallic RuII complexes of the type [(eta6-arene)Ru(XY)Cl]Z, where XY is an N,N- (diamine), N,O- (e.g., amino acidate), or O,O- (e.g., beta-diketonate) chelating ligand, the arene ranges from benzene derivatives to fused polycyclic hydrocarbons, and Z is usually PF6 [4].
• The structure of ([W3Q4X3(dmpe)3]+, Y-) ion pairs (Q = S, Se; X = H, OH, Br; Y = BF4, PF6, dmpe = Me2PCH2CH2PMe2) in dichloromethane solution and the effect of ion-pairing on the kinetics of proton transfer to the hydride cluster [W3S4H3(dmpe)3]+ [5].
• Single crystal X-ray structures of L1 and [RuII(bipy)2(L2H)](H2PO4)3.(CH3)2CO.0.8H2O were obtained, the latter revealing the presence of H2PO4- counter anions, the source of which is presumed to be hydrolysis of PF6- ions [6].
• Complexes of the type [Re(III)L6]X3, with L = thiourea, N-methylthiourea, N-ethylthiourea or N,N'-dimethytlthiourea and X = Cl- or PF6-, were prepared as suitable precursors for the synthesis of new rhenium complexes potentially useful in nuclear medicine [7].

Anatomical context of SPAG17

• The murine Pf6 gene is expressed in a pattern consistent with a role in flagella and cilia, and the PF6 protein is indeed localized to the central apparatus of the sperm flagellar axoneme [8].
• PF6, a component of the Chlamydomonas central apparatus, is localized to the 1a projection of the C1 microtubule [8].

Associations of SPAG17 with chemical compounds

• Carrier dynamics in conducting polymers: case of PF6 doped polypyrrole [9].
• Changing the counteranion along the series Br, BF4, PF6, SbF6 in their ion-paired 2-pyridylmethyl imidazolium salts causes the kinetic reaction products with IrH5(PPh3)2 to switch from chelating N-heterocyclic carbenes (NHCs) having normal C2 (N path) to abnormal C5 binding (AN path) [10].
• The conductance sequence for anion efflux was NO3 greater than SCN approximately ClO4 greater than Cl approximately I approximately Br greater than PF6 greater than F approximately HCO3 much greater than H2PO4 [11].
• The permeability sequence was SCN greater than I approximately NO3 approximately ClO4 greater than Br greater than Cl greater than PF6 greater than HCO3 approximately F much greater than H2PO4 [11].
• The quenching rate constants of the visible emission of [Au2(dcpm)2]2+ in acetonitrile by various anions are 6.08 x 10(5) (ClO4-), 9.18 x l0(5) (PF6 ), 1.55 x 10(7) (Cl-) and 4.06 x 10(9) (I-) mol(-1) dm3s(-1) [12].

Physical interactions of SPAG17

• Dissecting the axoneme interactome: the mammalian orthologue of Chlamydomonas PF6 interacts with sperm-associated antigen 6, the mammalian orthologue of Chlamydomonas PF16 [8].

Analytical, diagnostic and therapeutic context of SPAG17

• The absorption bands of [Cu2(dcpm)2]X2 and [Cu2(dcpm)2(CH3CN)2]X2 (X=ClO4- and PF6-) at lambda max 307-311 nm in CH2Cl2 are assigned as 1[3d sigma* --> 4p sigma] transitions; this has been confirmed by resonance Raman spectroscopy [13].
• The structural features of the bis-betaines 1, betaines 2 x PF6 and 5 x X, and the corresponding dicationic [1(4)]heterophanes 3 x 2X and 4 x 2Cl were studied by 1H and 13C NMR spectroscopy and electrospray ionization mass spectrometry, and confirmed by single-crystal X-ray diffraction analysis of macrocycles 1a and 2a x PF6 [14].
• The order of increasing ease of crystallization of the cluster salts was I- > PF6- approximately ClO4- > BF4- >> NO3-. The cluster structure is retained in alcohol and acetonitrile solutions; the UV-vis spectra of the solutions are perfectly consistent with the powder diffuse reflection spectrum [15].
• HPLC retention of perchlorate (ClO4-), tetrafluoroborate (BF4-), and hexafluorophosphate (PF6-) ions was studied on six columns with different bonded phases including alkyl, phenyl and perfluorophenyl phases [16].

References