Gene Review:
Adamts4 - a disintegrin-like and metallopeptidase...
Mus musculus
Synonyms:
3830423K05, A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS 4, ADAM-TS4, ADAMTS-2, ...
Doyle,
Charlotte J. East,
Oppers-Walgreen,
Belluoccio,
Little,
Kolls,
Mirna Z. Ilic,
Hernandez-Gonzalez,
Lo,
Fosang,
Bateman,
van den Bersselaar,
Boerboom,
Mittaz,
Meeker,
Helsen,
Koenders,
Campbell,
Thompson,
Pritchard,
Joosten,
Richards,
Sandy,
Fraser M. Rogerson,
LeBaron,
Rogerson,
Gonzalez-Robayna,
Christopher J. Handley,
van den Berg,
Teuling,
Lubberts,
Amanda J. Fosang,
Falender,
- Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Glasson, S.S., Askew, R., Sheppard, B., Carito, B., Blanchet, T., Ma, H.L., Flannery, C.R., Peluso, D., Kanki, K., Yang, Z., Majumdar, M.K., Morris, E.A. Nature (2005)
- Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice. Glasson, S.S., Askew, R., Sheppard, B., Carito, B.A., Blanchet, T., Ma, H.L., Flannery, C.R., Kanki, K., Wang, E., Peluso, D., Yang, Z., Majumdar, M.K., Morris, E.A. Arthritis Rheum. (2004)
- Expression of aggrecan(ases) during murine preadipocyte differentiation and adipose tissue development. Voros, G., Sandy, J.D., Collen, D., Lijnen, H.R. Biochim. Biophys. Acta (2006)
- Role of aggrecanase 1 in Lyme arthritis. Behera, A.K., Hildebrand, E., Szafranski, J., Hung, H.H., Grodzinsky, A.J., Lafyatis, R., Koch, A.E., Kalish, R., Perides, G., Steere, A.C., Hu, L.T. Arthritis Rheum. (2006)
- Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis. Majumdar, M.K., Askew, R., Schelling, S., Stedman, N., Blanchet, T., Hopkins, B., Morris, E.A., Glasson, S.S. Arthritis Rheum. (2007)
- ADAMTS-5 Deficiency Does Not Block Aggrecanolysis at Preferred Cleavage Sites in the Chondroitin Sulfate-rich Region of Aggrecan. East, C.J., Stanton, H., Golub, S.B., Rogerson, F.M., Fosang, A.J. J. Biol. Chem. (2007)
- ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo. Little, C.B., Mittaz, L., Belluoccio, D., Rogerson, F.M., Campbell, I.K., Meeker, C.T., Bateman, J.F., Pritchard, M.A., Fosang, A.J. Arthritis Rheum. (2005)
- Regulated expression of ADAMTS family members in follicles and cumulus oocyte complexes: evidence for specific and redundant patterns during ovulation. Richards, J.S., Hernandez-Gonzalez, I., Gonzalez-Robayna, I., Teuling, E., Lo, Y., Boerboom, D., Falender, A.E., Doyle, K.H., LeBaron, R.G., Thompson, V., Sandy, J.D. Biol. Reprod. (2005)
- Kinetics of aggrecanase- and metalloproteinase-induced neoepitopes in various stages of cartilage destruction in murine arthritis. van Meurs, J.B., van Lent, P.L., Holthuysen, A.E., Singer, I.I., Bayne, E.K., van den Berg, W.B. Arthritis Rheum. (1999)
- Transgenic mice with inactive alleles for procollagen N-proteinase (ADAMTS-2) develop fragile skin and male sterility. Li, S.W., Arita, M., Fertala, A., Bao, Y., Kopen, G.C., Långsjö, T.K., Hyttinen, M.M., Helminen, H.J., Prockop, D.J. Biochem. J. (2001)
- Aggrecanase and metalloproteinase-specific aggrecan neo-epitopes are induced in the articular cartilage of mice with collagen II-induced arthritis. Singer, I.I., Scott, S., Kawka, D.W., Bayne, E.K., Weidner, J.R., Williams, H.R., Mumford, R.A., Lark, M.W., McDonnell, J., Christen, A.J., Moore, V.L., Mudgett, J.S., Visco, D.M. Osteoarthr. Cartil. (1997)
- Hybridized and isosteric analogues of N1-acetyl-N4-dimethyl-piperazinium iodide (ADMP) and N1-phenyl-N4-dimethyl-piperazinium iodide (DMPP) with central nicotinic action. Manetti, D., Bartolini, A., Borea, P.A., Bellucci, C., Dei, S., Ghelardini, C., Gualtieri, F., Romanelli, M.N., Scapecchi, S., Teodori, E., Varani, K. Bioorg. Med. Chem. (1999)
- Distinguishing aggrecan loss from aggrecan proteolysis in ADAMTS-4 and ADAMTS-5 single and double deficient mice. Ilic, M.Z., East, C.J., Rogerson, F.M., Fosang, A.J., Handley, C.J. J. Biol. Chem. (2007)
- Gene deletion of either interleukin-1beta, interleukin-1beta-converting enzyme, inducible nitric oxide synthase, or stromelysin 1 accelerates the development of knee osteoarthritis in mice after surgical transection of the medial collateral ligament and partial medial meniscectomy. Clements, K.M., Price, J.S., Chambers, M.G., Visco, D.M., Poole, A.R., Mason, R.M. Arthritis Rheum. (2003)
- Induction of cartilage damage by overexpression of T cell interleukin-17A in experimental arthritis in mice deficient in interleukin-1. Koenders, M.I., Lubberts, E., Oppers-Walgreen, B., van den Bersselaar, L., Helsen, M.M., Kolls, J.K., Joosten, L.A., van den Berg, W.B. Arthritis Rheum. (2005)
- Matrix metalloproteinases and aggrecanases cleave aggrecan in different zones of normal cartilage but colocalize in the development of osteoarthritic lesions in STR/ort mice. Chambers, M.G., Cox, L., Chong, L., Suri, N., Cover, P., Bayliss, M.T., Mason, R.M. Arthritis Rheum. (2001)