Gene Review:
FTL - ferritin, light polypeptide
Homo sapiens
Synonyms:
Ferritin L subunit, Ferritin light chain, LFTD, MGC71996, NBIA3
Craig,
Clark,
McLeod,
Kirkland,
Grant,
Elder,
Toohey,
Kowal,
Savoia,
Chen,
Roberts,
Wirth,
Mackey,
Chen,
Langston,
Chan,
Brooks,
Manova-Todorova,
Farmer,
Lobmayr,
Wilson,
Eagle,
St Pierre,
Stambolian,
Vidal,
Ghetti,
Takao,
Brefel-Courbon,
Uro-Coste,
Glazier,
Siani,
Benson,
Calvas,
Miravalle,
Rascol,
Delisle,
- Ferritin light chain down-modulation generates depigmentation in human metastatic melanoma cells by influencing tyrosinase maturation. Maresca, V., Flori, E., Cardinali, G., Briganti, S., Lombardi, D., Mileo, A.M., Paggi, M.G., Picardo, M. J. Cell. Physiol. (2006)
- Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder. Cozzi, A., Santambrogio, P., Corsi, B., Campanella, A., Arosio, P., Levi, S. Neurobiol. Dis. (2006)
- Neuroferritinopathy: missense mutation in FTL causing early-onset bilateral pallidal involvement. Maciel, P., Cruz, V.T., Constante, M., Iniesta, I., Costa, M.C., Gallati, S., Sousa, N., Sequeiros, J., Coutinho, P., Santos, M.M. Neurology (2005)
- Discovery and analysis of inflammatory disease-related genes using cDNA microarrays. Heller, R.A., Schena, M., Chai, A., Shalon, D., Bedilion, T., Gilmore, J., Woolley, D.E., Davis, R.W. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Ferritin crystal cataracts in hereditary hyperferritinemia cataract syndrome. Brooks, D.G., Manova-Todorova, K., Farmer, J., Lobmayr, L., Wilson, R.B., Eagle, R.C., St Pierre, T.G., Stambolian, D. Invest. Ophthalmol. Vis. Sci. (2002)
- The prematurity stereotype in Israeli health care providers. Stern, M., Moritzen, S.K., Carmel, S., Olexa-Andrews, M. Medical education. (2001)
- STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line. Minami, M., Inoue, M., Wei, S., Takeda, K., Matsumoto, M., Kishimoto, T., Akira, S. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Human creatine kinase genes on chromosomes 15 and 19, and proximity of the gene for the muscle form to the genes for apolipoprotein C2 and excision repair. Stallings, R.L., Olson, E., Strauss, A.W., Thompson, L.H., Bachinski, L.L., Siciliano, M.J. Am. J. Hum. Genet. (1988)
- Human ferritin genes: chromosomal assignments and polymorphisms. Gatti, R.A., Shaked, R., Mohandas, T.K., Salser, W. Am. J. Hum. Genet. (1987)
- Structure of human ferritin light subunit messenger RNA: comparison with heavy subunit message and functional implications. Dörner, M.H., Salfeld, J., Will, H., Leibold, E.A., Vass, J.K., Munro, H.N. Proc. Natl. Acad. Sci. U.S.A. (1985)
- Hereditary hyperferritinemia-cataract syndrome: relationship between phenotypes and specific mutations in the iron-responsive element of ferritin light-chain mRNA. Cazzola, M., Bergamaschi, G., Tonon, L., Arbustini, E., Grasso, M., Vercesi, E., Barosi, G., Bianchi, P.E., Cairo, G., Arosio, P. Blood (1997)
- Cellular expression, localization and interactions of the product of the human MOST-1 gene associated with breast and prostate cancers. Tan, J.M., Chow, V.T. Int. J. Oncol. (2007)
- Iron regulation and the cell cycle: identification of an iron-responsive element in the 3'-untranslated region of human cell division cycle 14A mRNA by a refined microarray-based screening strategy. Sanchez, M., Galy, B., Dandekar, T., Bengert, P., Vainshtein, Y., Stolte, J., Muckenthaler, M.U., Hentze, M.W. J. Biol. Chem. (2006)
- Differential expression of insulin-like growth factor binding protein 1 and ferritin light polypeptide in gestational trophoblastic neoplasia: combined cDNA suppression subtractive hybridization and microarray study. Feng, H.C., Tsao, S.W., Ngan, H.Y., Xue, W.C., Chiu, P.M., Cheung, A.N. Cancer (2005)
- Intracellular ferritin accumulation in neural and extraneural tissue characterizes a neurodegenerative disease associated with a mutation in the ferritin light polypeptide gene. Vidal, R., Ghetti, B., Takao, M., Brefel-Courbon, C., Uro-Coste, E., Glazier, B.S., Siani, V., Benson, M.D., Calvas, P., Miravalle, L., Rascol, O., Delisle, M.B. J. Neuropathol. Exp. Neurol. (2004)
- Exclusion of ferritins and iron-responsive element (IRE)-binding proteins as candidates for the hemochromatosis gene. Zheng, H., Bhavsar, D., Volz, A., Ziegler, A., Drysdale, J. Hum. Genet. (1994)
- Assignment of ferritin L gene (FTL) to human chromosome band 19q13.3 by in situ hybridization. Gasparini, P., Calvano, S., Memeo, E., Bisceglia, L., Zelante, L. Ann. Genet. (1997)
- Screening of ferritin light polypeptide 460-461InsA mutation in Parkinson's disease patients in North America. Chen, R., Langston, J.W., Chan, P. Neurosci. Lett. (2002)
- The iron-binding protein ferritin is expressed in cells of the osteoblastic lineage in vitro and in vivo. Spanner, M., Weber, K., Lanske, B., Ihbe, A., Siggelkow, H., Schütze, H., Atkinson, M.J. Bone (1995)
- Proteomic approach to coronary atherosclerosis shows ferritin light chain as a significant marker: evidence consistent with iron hypothesis in atherosclerosis. You, S.A., Archacki, S.R., Angheloiu, G., Moravec, C.S., Rao, S., Kinter, M., Topol, E.J., Wang, Q. Physiol. Genomics (2003)
- A high-throughput screening system for genes extending life-span. Chen, C., Dewaele, S., Braeckman, B., Desmyter, L., Verstraelen, J., Borgonie, G., Vanfleteren, J., Contreras, R. Exp. Gerontol. (2003)
- Neuroferritinopathy: a window on the role of iron in neurodegeneration. Crompton, D.E., Chinnery, P.F., Fey, C., Curtis, A.R., Morris, C.M., Kierstan, J., Burt, A., Young, F., Coulthard, A., Curtis, A., Ince, P.G., Bates, D., Jackson, M.J., Burn, J. Blood Cells Mol. Dis. (2002)
- Nickel decreases cellular iron level and converts cytosolic aconitase to iron-regulatory protein 1 in A549 cells. Chen, H., Davidson, T., Singleton, S., Garrick, M.D., Costa, M. Toxicol. Appl. Pharmacol. (2005)
- Differential screening identifies genetic markers of monocyte to macrophage maturation. Krause, S.W., Rehli, M., Kreutz, M., Schwarzfischer, L., Paulauskis, J.D., Andreesen, R. J. Leukoc. Biol. (1996)
- Calculation of bioavailable and free testosterone in men: a comparison of 5 published algorithms. de Ronde, W., van der Schouw, Y.T., Pols, H.A., Gooren, L.J., Muller, M., Grobbee, D.E., de Jong, F.H. Clin. Chem. (2006)
- Microdissection, mRNA amplification and microarray: a study of pleural mesothelial and malignant mesothelioma cells. Mohr, S., Bottin, M.C., Lannes, B., Neuville, A., Bellocq, J.P., Keith, G., Rihn, B.H. Biochimie (2004)
- Use of the frequency-tracking locus in estimating the degree of respiratory entrainment in preterm infants. Bignall, S., Kitney, R.I., Summers, D. Physiological measurement. (1993)
- Hereditary hyperferritinemia-cataract syndrome: prevalence, lens morphology, spectrum of mutations, and clinical presentations. Craig, J.E., Clark, J.B., McLeod, J.L., Kirkland, M.A., Grant, G., Elder, J.E., Toohey, M.G., Kowal, L., Savoia, H.F., Chen, C., Roberts, S., Wirth, M.G., Mackey, D.A. Arch. Ophthalmol. (2003)
- Surface-enhanced laser desorption/ionization time of flight mass spectrometry protein profiling identifies ubiquitin and ferritin light chain as prognostic biomarkers in node-negative breast cancer tumors. Ricolleau, G., Charbonnel, C., Lodé, L., Loussouarn, D., Joalland, M.P., Bogumil, R., Jourdain, S., Minvielle, S., Campone, M., Déporte-Fety, R., Campion, L., Jézéquel, P. Proteomics (2006)