Gene Review:
GHRHR - growth hormone releasing hormone receptor
Homo sapiens
Synonyms:
GHRFR, GHRH receptor, GRF receptor, GRFR, Growth hormone-releasing factor receptor, ...
Salvatori,
Hayashida,
Aguiar-Oliveira,
Phillips,
Souza,
Gondo,
Toledo,
Conceicão,
Prince,
Maheshwari,
Baumann,
Levine,
Gallego,
Pintos,
García-Caballero,
Raghay,
Boulanger,
Beiras,
Gaudreau,
Morel,
Salvatori,
Fan,
Phillips,
Prince,
Levine,
Prins,
Fodor,
Delemarre-van de Waal,
Salvatori,
Fan,
Phillips,
Espigares-Martin,
Martin De Lara,
Freeman,
Plotnick,
Al-Ashwal,
Levine,
Gaylinn,
- Familial dwarfism due to a novel mutation of the growth hormone-releasing hormone receptor gene. Salvatori, R., Hayashida, C.Y., Aguiar-Oliveira, M.H., Phillips, J.A., Souza, A.H., Gondo, R.G., Toledo, S.P., Conceicão, M.M., Prince, M., Maheshwari, H.G., Baumann, G., Levine, M.A. J. Clin. Endocrinol. Metab. (1999)
- Stimulation of proliferation of MCF-7 breast cancer cells by a transfected splice variant of growth hormone-releasing hormone receptor. Barabutis, N., Tsellou, E., Schally, A.V., Kouloheri, S., Kalofoutis, A., Kiaris, H. Proc. Natl. Acad. Sci. U.S.A. (2007)
- Isolation and sequencing of cDNAs for splice variants of growth hormone-releasing hormone receptors from human cancers. Rekasi, Z., Czompoly, T., Schally, A.V., Halmos, G. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Identification of alternatively spliced messenger ribonucleic acid encoding truncated growth hormone-releasing hormone receptor in human pituitary adenomas. Hashimoto, K., Koga, M., Motomura, T., Kasayama, S., Kouhara, H., Ohnishi, T., Arita, N., Hayakawa, T., Sato, B., Kishimoto, T. J. Clin. Endocrinol. Metab. (1995)
- Neuroendocrine control of growth hormone secretion. Müller, E.E., Locatelli, V., Cocchi, D. Physiol. Rev. (1999)
- BamHI RFLP for the GHRHR locus. Cao, Y., Wagner, J.K., Eblé, A., Hindmarsh, P., Mullis, P.E. Hum. Mol. Genet. (1994)
- Cloning and characterization of the 5'-flanking region of the human growth hormone-releasing hormone receptor gene. Iguchi, G., Okimura, Y., Takahashi, T., Mizuno, I., Fumoto, M., Takahashi, Y., Kaji, H., Abe, H., Chihara, K. J. Biol. Chem. (1999)
- Three new mutations in the gene for the growth hormone (gh)-releasing hormone receptor in familial isolated gh deficiency type ib. Salvatori, R., Fan, X., Phillips, J.A., Espigares-Martin, R., Martin De Lara, I., Freeman, K.L., Plotnick, L., Al-Ashwal, A., Levine, M.A. J. Clin. Endocrinol. Metab. (2001)
- Familial Growth Hormone Deficiency and Mutations in the GHRH Receptor Gene. Alba, M., Salvatori, R. Vitam. Horm. (2004)
- A new missense mutation in the growth hormone-releasing hormone receptor gene in familial isolated GH deficiency. Carakushansky, M., Whatmore, A.J., Clayton, P.E., Shalet, S.M., Gleeson, H.K., Price, D.A., Levine, M.A., Salvatori, R. Eur. J. Endocrinol. (2003)
- Pituitary magnetic resonance imaging and function in patients with growth hormone deficiency with and without mutations in GHRH-R, GH-1, or PROP-1 genes. Osorio, M.G., Marui, S., Jorge, A.A., Latronico, A.C., Lo, L.S., Leite, C.C., Estefan, V., Mendonca, B.B., Arnhold, I.J. J. Clin. Endocrinol. Metab. (2002)
- Structure and regulation of the human growth hormone-releasing hormone receptor gene. Petersenn, S., Rasch, A.C., Heyens, M., Schulte, H.M. Mol. Endocrinol. (1998)
- Differential Regulation of GHRH-Receptor and GHS-Receptor Expression by Long-Term In Vitro Treatment of Ovine Pituitary Cells with GHRP-2 and GHRH. Roh, S.G., Doconto, M., Feng, D.D., Chen, C. Endocrine (2006)
- Pituitary growth hormone-releasing factor receptor expression in normal and dwarf rats. Carmignac, D.F., Flavell, D.M., Robinson, I.C. Neuroendocrinology (1996)
- Cellular distribution of growth hormone-releasing hormone receptor in human reproductive system and breast and prostate cancers. Gallego, R., Pintos, E., García-Caballero, T., Raghay, K., Boulanger, L., Beiras, A., Gaudreau, P., Morel, G. Histol. Histopathol. (2005)
- Internalization and trafficking of the human and rat growth hormone-releasing hormone receptor. Veyrat-Durebex, C., Pomerleau, L., Langlois, D., Gaudreau, P. J. Cell. Physiol. (2005)
- Absence of constitutively activating mutations in the GHRH receptor in GH-producing pituitary tumors. Lee, E.J., Kotlar, T.J., Ciric, I., Lee, M.K., Lim, S.K., Lee, H.C., Huh, K.B., Mayo, K.E., Jameson, J.L. J. Clin. Endocrinol. Metab. (2001)
- Hormonal control of growth hormone secretion. Pombo, M., Pombo, C.M., Garcia, A., Caminos, E., Gualillo, O., Alvarez, C.V., Casanueva, F.F., Dieguez, C. Horm. Res. (2001)
- Molecular and cell biology of the growth hormone-releasing hormone receptor. Gaylinn, B.D. Growth Horm. IGF Res. (1999)
- Growth hormone-releasing hormone and growth hormone-releasing peptide as therapeutic agents to enhance growth hormone secretion in disease and aging. Thorner, M.O., Chapman, I.M., Gaylinn, B.D., Pezzoli, S.S., Hartman, M.L. Recent Prog. Horm. Res. (1997)
- Inhibitory effects of antagonistic analogs of GHRH on GH3 pituitary cells overexpressing the human GHRH receptor. Kovacs, M., Schally, A.V., Lee, E.J., Busto, R., Armatis, P., Groot, K., Varga, J.L. J. Endocrinol. (2002)
- Mapping the human growth hormone-releasing hormone receptor (GHRHR) gene to the short arm of chromosome 7 (7p13-p21) near the epidermal growth factor receptor (EGFR) gene. Vamvakopoulos, N.C., Kunz, J., Olberding, U., Scherer, S.W., Sioutopoulou, T.O., Schneider, V., Durkin, A.S., Nierman, W.C. Genomics (1994)
- Pituitary mRNA expression of the growth hormone axis in the 1-year-old intrauterine growth restricted rat. Prins, T., Fodor, M., Delemarre-van de Waal, H.A. J. Neuroendocrinol. (2006)
- Assignment of the human growth hormone-releasing hormone receptor gene (GHRHR) to 7p14 by in situ hybridization. Gaylinn, B.D., von Kap-Herr, C., Golden, W.L., Thorner, M.O. Genomics (1994)
- Restoration of growth hormone-releasing hormone (GHRH) responsiveness in pituitary GH3 cells by adenovirus-directed expression of the human GHRH receptor. Lee, E.J., Duan, W.R., Kotlar, T., Jameson, J.L. Endocrinology (2001)
- Isolated growth hormone (GH) deficiency due to compound heterozygosity for two new mutations in the GH-releasing hormone receptor gene. Salvatori, R., Fan, X., Phillips, J.A., Prince, M., Levine, M.A. Clin. Endocrinol. (Oxf) (2001)