Gene Review:
BKRF1 - EBNA-1 protein
Human herpesvirus 4
- Nuclear import of Epstein-Barr virus nuclear antigen 1 mediated by NPI-1 (Importin alpha5) is up- and down-regulated by phosphorylation of the nuclear localization signal for which Lys379 and Arg380 are essential. Kitamura, R., Sekimoto, T., Ito, S., Harada, S., Yamagata, H., Masai, H., Yoneda, Y., Yanagi, K. J. Virol. (2006)
- Concomitant increase of LMP1 and CD25 (IL-2-receptor alpha) expression induced by IL-10 in the EBV-positive NK lines SNK6 and KAI3. Takahara, M., Kis, L.L., Nagy, N., Liu, A., Harabuchi, Y., Klein, G., Klein, E. Int. J. Cancer (2006)
- Three restricted forms of Epstein-Barr virus latency counteracting apoptosis in c-myc-expressing Burkitt lymphoma cells. Kelly, G.L., Milner, A.E., Baldwin, G.S., Bell, A.I., Rickinson, A.B. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Murine cytotoxic T lymphocytes recognize an epitope in an EBNA-1 fragment, but fail to lyse EBNA-1-expressing mouse cells. Mukherjee, S., Trivedi, P., Dorfman, D.M., Klein, G., Townsend, A. J. Exp. Med. (1998)
- EBNA-1, the major nuclear antigen of Epstein-Barr virus, resembles 'RGG' RNA binding proteins. Snudden, D.K., Hearing, J., Smith, P.R., Grässer, F.A., Griffin, B.E. EMBO J. (1994)
- Epstein-Barr virus nuclear antigen-1 and Myc cooperate in lymphomagenesis. Drotar, M.E., Silva, S., Barone, E., Campbell, D., Tsimbouri, P., Jurvansu, J., Bhatia, P., Klein, G., Wilson, J.B. Int. J. Cancer (2003)
- Crystal structure of the DNA-binding domain of the Epstein-Barr virus origin-binding protein, EBNA1, bound to DNA. Bochkarev, A., Barwell, J.A., Pfuetzner, R.A., Bochkareva, E., Frappier, L., Edwards, A.M. Cell (1996)
- Sequence-specific DNA binding of the Epstein-Barr virus nuclear antigen (EBNA-1) to clustered sites in the plasmid maintenance region. Rawlins, D.R., Milman, G., Hayward, S.D., Hayward, G.S. Cell (1985)
- Epstein-Barr virus-associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2. Kelly, G., Bell, A., Rickinson, A. Nat. Med. (2002)
- Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells. Maruo, S., Wu, Y., Ishikawa, S., Kanda, T., Iwakiri, D., Takada, K. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Genetic evidence that EBNA-1 is needed for efficient, stable latent infection by Epstein-Barr virus. Lee, M.A., Diamond, M.E., Yates, J.L. J. Virol. (1999)
- Construction and properties of an Epstein-Barr-virus-derived cDNA expression vector for human cells. Belt, P.B., Groeneveld, H., Teubel, W.J., van de Putte, P., Backendorf, C. Gene (1989)
- Expression of the Epstein-Barr virus nuclear antigen-1 (EBNA-1) in the mouse can elicit the production of anti-dsDNA and anti-Sm antibodies. Sundar, K., Jacques, S., Gottlieb, P., Villars, R., Benito, M.E., Taylor, D.K., Spatz, L.A. J. Autoimmun. (2004)
- Regulation of Epstein-Barr virus latency type by the chromatin boundary factor CTCF. Chau, C.M., Zhang, X.Y., McMahon, S.B., Lieberman, P.M. J. Virol. (2006)
- Epigenotypes of latent herpesvirus genomes. Minarovits, J. Curr. Top. Microbiol. Immunol. (2006)
- Epstein-Barr Virus EBNA-3C Is Targeted to and Regulates Expression from the Bidirectional LMP-1/2B Promoter. Jim??nez-Ram??rez, C., Brooks, A.J., Forshell, L.P., Yakimchuk, K., Zhao, B., Fulgham, T.Z., Sample, C.E. J. Virol. (2006)
- Quantitative profiling of housekeeping and Epstein-Barr virus gene transcription in Burkitt lymphoma cell lines using an oligonucleotide microarray. Bernasconi, M., Berger, C., Sigrist, J.A., Bonanomi, A., Sobek, J., Niggli, F.K., Nadal, D. Virol. J. (2006)
- Detection of Epstein-Barr virus in invasive breast cancers. Bonnet, M., Guinebretiere, J.M., Kremmer, E., Grunewald, V., Benhamou, E., Contesso, G., Joab, I. J. Natl. Cancer Inst. (1999)
- Rheumatoid arthritis synovial membrane contains a 62,000-molecular-weight protein that shares an antigenic epitope with the Epstein-Barr virus-encoded associated nuclear antigen. Fox, R., Sportsman, R., Rhodes, G., Luka, J., Pearson, G., Vaughan, J. J. Clin. Invest. (1986)
- trans activation of an Epstein-Barr viral transcriptional enhancer by the Epstein-Barr viral nuclear antigen 1. Reisman, D., Sugden, B. Mol. Cell. Biol. (1986)
- Deiminated Epstein-Barr virus nuclear antigen 1 is a target of anti-citrullinated protein antibodies in rheumatoid arthritis. Pratesi, F., Tommasi, C., Anzilotti, C., Chimenti, D., Migliorini, P. Arthritis Rheum. (2006)
- The minimal replicator of Epstein-Barr virus oriP. Yates, J.L., Camiolo, S.M., Bashaw, J.M. J. Virol. (2000)
- Expression of EBNA-1 mRNA is regulated by cell cycle during Epstein-Barr virus type I latency. Davenport, M.G., Pagano, J.S. J. Virol. (1999)
- An Epstein Barr virus-related cross reactive autoimmune response in multiple sclerosis in Norway. Vaughan, J.H., Riise, T., Rhodes, G.H., Nguyen, M.D., Barrett-Connor, E., Nyland, H. J. Neuroimmunol. (1996)
- Epstein-Barr viral DNA in acute large granular lymphocyte (natural killer) leukemic cells. Hart, D.N., Baker, B.W., Inglis, M.J., Nimmo, J.C., Starling, G.C., Deacon, E., Rowe, M., Beard, M.E. Blood (1992)
- Noninvasive diagnosis of nasopharyngeal carcinoma: nasopharyngeal brushings reveal high Epstein-Barr virus DNA load and carcinoma-specific viral BARF1 mRNA. Stevens, S.J., Verkuijlen, S.A., Hariwiyanto, B., Harijadi, n.u.l.l., Paramita, D.K., Fachiroh, J., Adham, M., Tan, I.B., Haryana, S.M., Middeldorp, J.M. Int. J. Cancer (2006)
- Analysis of Epstein-Barr virus latent gene expression in endemic Burkitt's lymphoma and nasopharyngeal carcinoma tumour cells by using quantitative real-time PCR assays. Bell, A.I., Groves, K., Kelly, G.L., Croom-Carter, D., Hui, E., Chan, A.T., Rickinson, A.B. J. Gen. Virol. (2006)
- Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis. Cepok, S., Zhou, D., Srivastava, R., Nessler, S., Stei, S., Büssow, K., Sommer, N., Hemmer, B. J. Clin. Invest. (2005)
- Increased levels of circulating Epstein-Barr virus (EBV)-infected lymphocytes and decreased EBV nuclear antigen antibody responses are associated with the development of posttransplant lymphoproliferative disease in solid-organ transplant recipients. Riddler, S.A., Breinig, M.C., McKnight, J.L. Blood (1994)
- Surface plasmon resonance biosensor for direct detection of antibody against Epstein-Barr virus. Vaisocherov??, H., Mrkvov??, K., Piliarik, M., Jinoch, P., Steinbachov??, M., Homola, J. Biosensors & bioelectronics (2007)
- Multiplex-nested RT-PCR to evaluate latent and lytic Epstein Barr virus gene expression. Bergallo, M., Costa, C., Baro, S., Musso, T., Balbo, L., Merlino, C., Cavallo, R. J. Biotechnol. (2007)
- Infection of Epstein-Barr virus in Colorectal Cancer in Chinese. Song, L.B., Zhang, X., Zhang, C.Q., Zhang, Y., Pan, Z.Z., Liao, W.T., Li, M.Z., Zeng, M.S. Ai Zheng (2006)
- EBV gene expression in an NPC-related tumour. Hitt, M.M., Allday, M.J., Hara, T., Karran, L., Jones, M.D., Busson, P., Tursz, T., Ernberg, I., Griffin, B.E. EMBO J. (1989)