Gene Review:
gig - gigas
Drosophila melanogaster
Synonyms:
6975, C1, CG6975, Dmel\CG6975, Gigas, ...
- gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle. Ito, N., Rubin, G.M. Cell (1999)
- Rhebbing up mTOR: new insights on TSC1 and TSC2, and the pathogenesis of tuberous sclerosis. Kwiatkowski, D.J. Cancer Biol. Ther. (2003)
- Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas. Romão, M.J., Archer, M., Moura, I., Moura, J.J., LeGall, J., Engh, R., Schneider, M., Hof, P., Huber, R. Science (1995)
- Promoters from Drosophila heat shock protein and cytomegalovirus drive transient expression of luciferase introduced by particle bombardment into embryos of the oyster Crassostrea gigas. Cadoret, J.P., Boulo, V., Gendreau, S., Mialhe, E. J. Biotechnol. (1997)
- Immune gene discovery by expressed sequence tags generated from hemocytes of the bacteria-challenged oyster, Crassostrea gigas. Gueguen, Y., Cadoret, J.P., Flament, D., Barreau-Roumiguière, C., Girardot, A.L., Garnier, J., Hoareau, A., Bachère, E., Escoubas, J.M. Gene (2003)
- The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation. Tapon, N., Ito, N., Dickson, B.J., Treisman, J.E., Hariharan, I.K. Cell (2001)
- Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Potter, C.J., Huang, H., Xu, T. Cell (2001)
- Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling. Radimerski, T., Montagne, J., Hemmings-Mieszczak, M., Thomas, G. Genes Dev. (2002)
- Tsc2 is not a critical target of Akt during normal Drosophila development. Dong, J., Pan, D. Genes Dev. (2004)
- TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth. Gao, X., Pan, D. Genes Dev. (2001)
- Single neuron mosaics of the drosophila gigas mutant project beyond normal targets and modify behavior. Canal, I., Acebes, A., Ferrús, A. J. Neurosci. (1998)
- Tuberous sclerosis causing mutants of the TSC2 gene product affect proliferation and p27 expression. Soucek, T., Rosner, M., Miloloza, A., Kubista, M., Cheadle, J.P., Sampson, J.R., Hengstschläger, M. Oncogene (2001)
- Cg-Rel, the first Rel/NF-kappaB homolog characterized in a mollusk, the Pacific oyster Crassostrea gigas. Montagnani, C., Kappler, C., Reichhart, J.M., Escoubas, J.M. FEBS Lett. (2004)
- Structure and expression of mGDF, a new member of the transforming growth factor-beta superfamily in the bivalve mollusc Crassostrea gigas. Lelong, C., Mathieu, M., Favrel, P. Eur. J. Biochem. (2000)
- Properties of xanthine dehydrogenase variants from rosy mutant strains of Drosophila melanogaster and their relevance to the enzyme's structure and mechanism. Doyle, W.A., Burke, J.F., Chovnick, A., Dutton, F.L., Whittle, J.R., Bray, R.C. Eur. J. Biochem. (1996)