MeSH Review:
Hamartoma
Cantley,
Neel,
Kerfoot,
Wienecke,
Menchine,
Emelin,
Maize,
Welsh,
Norman,
DeClue,
Vinters,
Kwiatkowski,
Manning,
Leal,
Moreira,
Robalo,
Ribeiro,
Silva,
Frankland,
Marowitz,
Friedman,
Laszlo,
Cioffi,
Jacks,
Bourtchuladze,
Lazlo,
Lamb,
Roy,
Diefenbach,
Vinters,
Johnson,
Jay,
Hall,
Kwiatkowski,
Zhang,
Bandura,
Heiberger,
Glogauer,
el-Hashemite,
Onda,
- Hypothalamic hamartoma: a source of luteinizing-hormone-releasing factor in precocious puberty. Judge, D.M., Kulin, H.E., Page, R., Santen, R., Trapukdi, S. N. Engl. J. Med. (1977)
- Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients. Green, A.J., Smith, M., Yates, J.R. Nat. Genet. (1994)
- Dysregulation of the TSC-mTOR pathway in human disease. Inoki, K., Corradetti, M.N., Guan, K.L. Nat. Genet. (2005)
- Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease. Backman, S.A., Stambolic, V., Suzuki, A., Haight, J., Elia, A., Pretorius, J., Tsao, M.S., Shannon, P., Bolon, B., Ivy, G.O., Mak, T.W. Nat. Genet. (2001)
- A mouse model for the learning and memory deficits associated with neurofibromatosis type I. Silva, A.J., Frankland, P.W., Marowitz, Z., Friedman, E., Laszlo, G.S., Cioffi, D., Jacks, T., Bourtchuladze, R., Lazlo, G. Nat. Genet. (1997)
- The molecular genetics of tuberous sclerosis. Sampson, J.R., Harris, P.C. Hum. Mol. Genet. (1994)
- Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background. Onda, H., Lueck, A., Marks, P.W., Warren, H.B., Kwiatkowski, D.J. J. Clin. Invest. (1999)
- Gelastic epilepsy caused by hypothalamic hamartoma. Engelborghs, S., Mariën, P., De Deyn, P.P. Lancet (2000)
- Survey of somatic mutations in tuberous sclerosis complex (TSC) hamartomas suggests different genetic mechanisms for pathogenesis of TSC lesions. Niida, Y., Stemmer-Rachamimov, A.O., Logrip, M., Tapon, D., Perez, R., Kwiatkowski, D.J., Sims, K., MacCollin, M., Louis, D.N., Ramesh, V. Am. J. Hum. Genet. (2001)
- Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways. Kwiatkowski, D.J., Manning, B.D. Hum. Mol. Genet. (2005)
- Localization of tuberous sclerosis 2 mRNA and its protein product tuberin in normal human brain and in cerebral lesions of patients with tuberous sclerosis. Kerfoot, C., Wienecke, R., Menchine, M., Emelin, J., Maize, J.C., Welsh, C.T., Norman, M.G., DeClue, J.E., Vinters, H.V. Brain Pathol. (1996)
- Hypothalamic hamartomas and gelastic epilepsy: a spectroscopic study. Tasch, E., Cendes, F., Li, L.M., Dubeau, F., Montes, J., Rosenblatt, B., Andermann, F., Arnold, D. Neurology (1998)
- Expression of NF2-encoded merlin and related ERM family proteins in the human central nervous system. Stemmer-Rachamimov, A.O., Gonzalez-Agosti, C., Xu, L., Burwick, J.A., Beauchamp, R., Pinney, D., Louis, D.N., Ramesh, V. J. Neuropathol. Exp. Neurol. (1997)
- Hypothalamic hamartomas: Correlation of MR imaging and spectroscopic findings with tumor glial content. Amstutz, D.R., Coons, S.W., Kerrigan, J.F., Rekate, H.L., Heiserman, J.E. AJNR. American journal of neuroradiology. (2006)
- Neuromuscular choristoma of the sciatic nerve. Case report. Maher, C.O., Spinner, R.J., Giannini, C., Scheithauer, B.W., Crum, B.A. J. Neurosurg. (2002)
- The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho. Lamb, R.F., Roy, C., Diefenbach, T.J., Vinters, H.V., Johnson, M.W., Jay, D.G., Hall, A. Nat. Cell Biol. (2000)
- Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes. Zhou, X., Hampel, H., Thiele, H., Gorlin, R.J., Hennekam, R.C., Parisi, M., Winter, R.M., Eng, C. Lancet (2001)
- The tuberous sclerosis gene on chromosome 9q34 acts as a growth suppressor. Green, A.J., Johnson, P.H., Yates, J.R. Hum. Mol. Genet. (1994)
- New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Cantley, L.C., Neel, B.G. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Expression of the PTEN tumour suppressor protein during human development. Gimm, O., Attié-Bitach, T., Lees, J.A., Vekemans, M., Eng, C. Hum. Mol. Genet. (2000)
- Colonic hamartoma development by anomalous duplication in Cdx2 knockout mice. Tamai, Y., Nakajima, R., Ishikawa, T., Takaku, K., Seldin, M.F., Taketo, M.M. Cancer Res. (1999)
- Neuropathology and molecular genetics of neurofibromatosis 2 and related tumors. Louis, D.N., Ramesh, V., Gusella, J.F. Brain Pathol. (1995)
- Adrenal medullary tumors and iris proliferation in a transgenic mouse model of neurofibromatosis. Green, J.E., Baird, A.M., Hinrichs, S.H., Klintworth, G.K., Jay, G. Am. J. Pathol. (1992)
- Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2. Manning, B.D., Logsdon, M.N., Lipovsky, A.I., Abbott, D., Kwiatkowski, D.J., Cantley, L.C. Genes Dev. (2005)
- A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells. Kwiatkowski, D.J., Zhang, H., Bandura, J.L., Heiberger, K.M., Glogauer, M., el-Hashemite, N., Onda, H. Hum. Mol. Genet. (2002)
- Cyclooxygenase 2 expression and molecular alterations in Peutz-Jeghers hamartomas and carcinomas. De Leng, W.W., Westerman, A.M., Weterman, M.A., De Rooij, F.W., Dekken Hv, H., De Goeij, A.F., Gruber, S.B., Wilson, J.H., Offerhaus, G.J., Giardiello, F.M., Keller, J.J. Clin. Cancer Res. (2003)
- Variant translocation t(6;10)(p21;q22) in pulmonary chondroid hamartoma. Minoletti, F., Sozzi, G., Calderone, C., Di Palma, S., Pilotti, S., Azzarelli, A., Pierotti, M.A. Genes Chromosomes Cancer (1996)
- Different electroclinical manifestations of the epilepsy associated with hamartomas connecting to the middle or posterior hypothalamus. Leal, A.J., Moreira, A., Robalo, C., Ribeiro, C. Epilepsia (2003)