Disease relevance of LSAMP

• The t(1;3) breakpoint-spanning genes LSAMP and NORE1 are involved in clear cell renal cell carcinomas [1].
• Recently, two members, OPCML and LSAMP, were identified as putative tumour suppressor genes in ovarian and renal carcinomas respectively [2].
• Trial lens fitting was performed 1 to 7 days later using a Burton Lamp. None of the patients developed keratitis, corneal neovascularization, or the sucked-on-lens syndrome [3].

Psychiatry related information on LSAMP

• This issue of The Lamp acknowledges the important contribution of mental health nurses to the profession of nursing [4].

High impact information on LSAMP

• The limbic system-associated membrane protein (LAMP) is confined chiefly to basal ganglia sectors that are anatomically and functionally related to limbic system structures; these may serve as functional interfaces between the basal ganglia and the limbic system [5].
• The expression levels of individual IgLONs were correlated, the most significant finding being a positive correlation between LSAMP and NEGR1 [6].
• These results reveal that the limbic system-associated membrane protein labels structures that form the core of the limbic system in primates [7].
• Limbic system-associated membrane protein (LAMP) in primate amygdala and hippocampus [7].
• Distribution of the limbic system-associated membrane protein (LAMP) in pigeon forebrain and midbrain [8].

Biological context of LSAMP

• Expression of LSAMP and NORE1A proteins in CCRCC cell lines inhibited cell proliferation [1].
• While the NORE1A promoter predominantly presents partial methylation in 6 of the cell lines and 17/53 (32%) primary tumors, the LSAMP promoter is completely methylated in 5 of 9 cell lines and in 14/53 (26%) sporadic and 4 familial CCRCCs [1].
• The epidemiology of burns, challenges faced in their management and effective strategies specific to Sri Lanka, such as the Safe Bottle Lamp campaign, are highlighted in this paper [9].

Anatomical context of LSAMP

• The limbic-system-associated membrane protein (LAMP) is a 64-68-kDa neuronal surface glycoprotein distributed in cortical and subcortical regions of the limbic system [10].
• The limbic system-associated membrane protein (LAMP) is an adhesion molecule involved in specifying regional identity during development, and it is enriched in the neuropil of limbic brain regions in mammals but also found in some somatic structures [8].
• The expression of the limbic system-associated membrane protein (LAMP), a marker of specific functional regions of the cerebral cortex, has been used to determine the environmental signals that regulate cortical regionalization [11].
• The Wood's Lamp, a UV light that causes semen to fluoresce, and four forensic laboratory techniques were compared to determine their sensitivity and decline in sensitivity over time [12].

Associations of LSAMP with chemical compounds

• Aerobic Oxidation of Benzyl- and Allylic Alcohols under Visible Light Irradiation of a Fluorescent Lamp in the Presence of Catalytic Iodine [13].

Analytical, diagnostic and therapeutic context of LSAMP

• The volunteers took the incremental exercise test (Ordinary Lamp Protocol) on a cycle ergometer to exhaustion, then rested according to the above assigned groups [14].
• Samples of the dried semen were assessed during a 28-hour period with the Wood's Lamp, microscopy, the acid phosphatase assay, and two assays for the prostatic protein p30 (counterimmunoelectrophoresis and enzyme-linked immunosorbent assay) [12].

References