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Gene Review

NR3C1  -  nuclear receptor subfamily 3, group C,...

Ovis aries

Synonyms: GR, GRL
 
 
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Disease relevance of NR3C1

 

High impact information on NR3C1

 

Biological context of NR3C1

 

Anatomical context of NR3C1

 

Associations of NR3C1 with chemical compounds

 

Other interactions of NR3C1

 

Analytical, diagnostic and therapeutic context of NR3C1

References

  1. Maternal undernutrition during early to midgestation programs tissue-specific alterations in the expression of the glucocorticoid receptor, 11beta-hydroxysteroid dehydrogenase isoforms, and type 1 angiotensin ii receptor in neonatal sheep. Whorwood, C.B., Firth, K.M., Budge, H., Symonds, M.E. Endocrinology (2001) [Pubmed]
  2. Antenatal glucocorticoids reset the level of baseline and hypoxemia-induced pituitary-adrenal activity in the sheep fetus during late gestation. Fletcher, A.J., Ma, X.H., Wu, W.X., Nathanielsz, P.W., McGarrigle, H.H., Fowden, A.L., Giussani, D.A. Am. J. Physiol. Endocrinol. Metab. (2004) [Pubmed]
  3. Changes of pulmonary glucocorticoid receptor and phospholipase A2 in sheep with acute lung injury after high dose endotoxin infusion. Liu, L.Y., Sun, B., Tian, Y., Lu, B.Z., Wang, J. Am. Rev. Respir. Dis. (1993) [Pubmed]
  4. New insights regarding glucocorticoids, stress and gonadotropin suppression. Breen, K.M., Karsch, F.J. Frontiers in neuroendocrinology. (2006) [Pubmed]
  5. Glucocorticoids downregulate cyclooxygenase-1 gene expression and prostacyclin synthesis in fetal pulmonary artery endothelium. Jun, S.S., Chen, Z., Pace, M.C., Shaul, P.W. Circ. Res. (1999) [Pubmed]
  6. Does cortisol acting via the type II glucocorticoid receptor mediate suppression of pulsatile luteinizing hormone secretion in response to psychosocial stress? Breen, K.M., Oakley, A.E., Pytiak, A.V., Tilbrook, A.J., Wagenmaker, E.R., Karsch, F.J. Endocrinology (2007) [Pubmed]
  7. Ontogeny and nutritional programming of uncoupling protein-2 and glucocorticoid receptor mRNA in the ovine lung. Gnanalingham, M.G., Mostyn, A., Dandrea, J., Yakubu, D.P., Symonds, M.E., Stephenson, T. J. Physiol. (Lond.) (2005) [Pubmed]
  8. Changes in glucocorticoid receptor number in the hypothalamus and pituitary of the sheep fetus with gestational age and after adrenocorticotropin treatment. Yang, K., Jones, S.A., Challis, J.R. Endocrinology (1990) [Pubmed]
  9. Tissue distribution of alpha 1-proteinase inhibitor messenger ribonucleic acid and its regulation by glucocorticoids in fetal and neonatal sheep. Berdusco, E.T., Yang, K., Challis, J.R., Hammond, G.L. Biol. Reprod. (1993) [Pubmed]
  10. Hepatic and splenic phagocytosis in female B6C3F1 mice implanted with morphine sulfate pellets. Levier, D.G., Brown, R.D., McCay, J.A., Fuchs, B.A., Harris, L.S., Munson, A.E. J. Pharmacol. Exp. Ther. (1993) [Pubmed]
  11. Sex differences in response to steroids in preterm sheep lungs are not explained by glucocorticoid receptor number or binding affinity. Kovar, J., Waddell, B.J., Sly, P.D., Willet, K.E. Pediatr. Pulmonol. (2001) [Pubmed]
  12. Characterization of an ovine glucocorticoid receptor cDNA and developmental changes in its mRNA levels in the fetal sheep hypothalamus, pituitary gland and adrenal. Yang, K., Hammond, G.L., Challis, J.R. J. Mol. Endocrinol. (1992) [Pubmed]
  13. Increased uncoupling protein-2 mRNA abundance and glucocorticoid action in adipose tissue in the sheep fetus during late gestation is dependent on plasma cortisol and triiodothyronine. Gnanalingham, M.G., Mostyn, A., Forhead, A.J., Fowden, A.L., Symonds, M.E., Stephenson, T. J. Physiol. (Lond.) (2005) [Pubmed]
  14. Effects of glucocorticoids on estrogen receptor messenger ribonucleic acid in the pregnant ovine myometrium in vivo and in vitro. Wu, W.X., Derks, J.B., Nathanielsz, P.W. Biol. Reprod. (1996) [Pubmed]
  15. Progesterone receptor, estrogen receptor alpha, and the type II glucocorticoid receptor are coexpressed in the same neurons of the ovine preoptic area and arcuate nucleus: a triple immunolabeling study. Dufourny, L., Skinner, D.C. Biol. Reprod. (2002) [Pubmed]
  16. Does the type II glucocorticoid receptor mediate cortisol-induced suppression in pituitary responsiveness to gonadotropin-releasing hormone? Breen, K.M., Stackpole, C.A., Clarke, I.J., Pytiak, A.V., Tilbrook, A.J., Wagenmaker, E.R., Young, E.A., Karsch, F.J. Endocrinology (2004) [Pubmed]
  17. Chronic umbilical cord compression results in accelerated maturation of lung and brown adipose tissue in the sheep fetus during late gestation. Gnanalingham, M.G., Giussani, D.A., Sivathondan, P., Forhead, A.J., Stephenson, T., Symonds, M.E., Gardner, D.S. Am. J. Physiol. Endocrinol. Metab. (2005) [Pubmed]
  18. Developmental changes and molecular weight of immunoreactive glucocorticoid receptor protein in the ovine fetal hypothalamus and pituitary. Saoud, C.J., Wood, C.E. Biochem. Biophys. Res. Commun. (1996) [Pubmed]
  19. Effects of cortisol and estradiol on pituitary expression of proopiomelanocortin, prohormone convertase-1, prohormone convertase-2, and glucocorticoid receptor mRNA in fetal sheep. Holloway, A.C., Whittle, W.L., Challis, J.R. Endocrine (2001) [Pubmed]
  20. Effects of cortisol and oestradiol on hepatic 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptor proteins in late-gestation sheep fetus. Gupta, S., Alfaidy, N., Holloway, A.C., Whittle, W.L., Lye, S.J., Gibb, W., Challis, J.R. J. Endocrinol. (2003) [Pubmed]
  21. Changes in glucocorticoid receptor mRNA in the developing ovine pituitary and the effects of exogenous cortisol. Matthews, S.G., Yang, K., Challis, J.R. J. Endocrinol. (1995) [Pubmed]
 
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