Gene Review:
POLR2A - polymerase (RNA) II (DNA directed)...
Homo sapiens
Synonyms:
DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, POLR2, POLRA, ...
- Interactions between the human RNA polymerase II subunits. Acker, J., de Graaff, M., Cheynel, I., Khazak, V., Kedinger, C., Vigneron, M. J. Biol. Chem. (1997)
- Evolution of the RNA polymerase II C-terminal domain. Stiller, J.W., Hall, B.D. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Amitochondriate amoebae and the evolution of DNA-dependent RNA polymerase II. Stiller, J.W., Duffield, E.C., Hall, B.D. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Role for the Ssu72 C-terminal domain phosphatase in RNA polymerase II transcription elongation. Reyes-Reyes, M., Hampsey, M. Mol. Cell. Biol. (2007)
- The human gene encoding the largest subunit of RNA polymerase II. Mita, K., Tsuji, H., Morimyo, M., Takahashi, E., Nenoi, M., Ichimura, S., Yamauchi, M., Hongo, E., Hayashi, A. Gene (1995)
- Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome. Bieda, M., Xu, X., Singer, M.A., Green, R., Farnham, P.J. Genome Res. (2006)
- BRCA1/BARD1 ubiquitinate phosphorylated RNA polymerase II. Starita, L.M., Horwitz, A.A., Keogh, M.C., Ishioka, C., Parvin, J.D., Chiba, N. J. Biol. Chem. (2005)
- In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitin. Nguyen, V.T., Giannoni, F., Dubois, M.F., Seo, S.J., Vigneron, M., Kédinger, C., Bensaude, O. Nucleic Acids Res. (1996)
- Evaluation of LNA-modified DNAzymes targeting a single nucleotide polymorphism in the large subunit of RNA polymerase II. Fluiter, K., Frieden, M., Vreijling, J., Koch, T., Baas, F. Oligonucleotides. (2005)
- A mutation in the largest (catalytic) subunit of RNA polymerase II and its relation to the arrest of the cell cycle in G(1) phase. Sugaya, K., Sasanuma, S., Cook, P.R., Mita, K. Gene (2001)
- The largest subunit of RNA polymerase II from the Glaucocystophyta: functional constraint and short-branch exclusion in deep eukaryotic phylogeny. Stiller, J.W., Harrell, L. BMC Evol. Biol. (2005)
- Validation of real-time reverse-transcription-polymerase chain reaction for quantification of capecitabine-metabolizing enzymes. Macpherson, J.S., Jodrell, D.I., Guichard, S.M. Anal. Biochem. (2006)
- ELA1 and CUL3 Are Required Along with ELC1 for RNA Polymerase II Polyubiquitylation and Degradation in DNA-Damaged Yeast Cells. Ribar, B., Prakash, L., Prakash, S. Mol. Cell. Biol. (2007)
- A novel hydrogen peroxide-induced phosphorylation and ubiquitination pathway leading to RNA polymerase II proteolysis. Inukai, N., Yamaguchi, Y., Kuraoka, I., Yamada, T., Kamijo, S., Kato, J., Tanaka, K., Handa, H. J. Biol. Chem. (2004)
- Foraminifera and Cercozoa share a common origin according to RNA polymerase II phylogenies. Longet, D., Archibald, J.M., Keeling, P.J., Pawlowski, J. Int. J. Syst. Evol. Microbiol. (2003)
- The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9. Lavoie, S.B., Albert, A.L., Handa, H., Vincent, M., Bensaude, O. J. Mol. Biol. (2001)
- Interactions between the full complement of human RNA polymerase II subunits. Schaller, S., Grandemange, S., Shpakovski, G.V., Golemis, E.A., Kedinger, C., Vigneron, M. FEBS Lett. (1999)
- The highly conserved glutamic acid 791 of Rpb2 is involved in the binding of NTP and Mg(B) in the active center of human RNA polymerase II. Langelier, M.F., Baali, D., Trinh, V., Greenblatt, J., Archambault, J., Coulombe, B. Nucleic Acids Res. (2005)
- Probing Zn2+-binding effects on the zinc-ribbon domain of human general transcription factor TFIIB. Ghosh, M., Elsby, L.M., Mal, T.K., Gooding, J.M., Roberts, S.G., Ikura, M. Biochem. J. (2004)
- Evidence that the Tfg1/Tfg2 dimer interface of TFIIF lies near the active center of the RNA polymerase II initiation complex. Freire-Picos, M.A., Krishnamurthy, S., Sun, Z.W., Hampsey, M. Nucleic Acids Res. (2005)